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View Structure Prediction Details

Protein: TAD3
Organism: Saccharomyces cerevisiae
Length: 322 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAD3.

Description E-value Query
Range
Subject
Range
TAD3 - Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad2p that converts adenos...
TAD3_YEAST - tRNA-specific adenosine deaminase subunit TAD3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
1.0E-89 [1..322] [1..322]
gi|45199011, gi|... - gi|45199011|ref|NP_986040.1| AFR493Cp [Ashbya gossypii ATCC 10895], gi|44985086|gb|AAS53864.1| AFR49...
gi|44985086 - gi|44985086|gb|AAS53864.1| AFR493Cp [Ashbya gossypii ATCC 10895]
4.0E-73 [1..322] [1..324]
ADAT3_DANRE - Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Danio rerio GN=adat3 PE=2 SV=2
2.0E-58 [8..318] [3..336]
gi|68476669, gi|... - gi|68476816|ref|XP_717553.1| potential tRNA wobble position adenosine deaminase subunit [Candida alb...
orf19.12556, orf... - orf19.5090 CGDID:CAL0001811 Assembly 19, Contig19-10218 (79509, 80489) CDS, translated using codon t...
1.0E-54 [9..321] [6..321]
ADAT3_MOUSE - Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Mus musculus GN=Adat3 PE=1 SV=...
4.0E-54 [23..315] [29..345]
ADAT3 - adenosine deaminase, tRNA-specific 3, TAD3 homolog (S. cerevisiae)
2.0E-53 [23..313] [29..345]
gi|42545037, gi|... - gi|46109124|ref|XP_381620.1| hypothetical protein FG01444.1 [Gibberella zeae PH-1], gi|42545037|gb|E...
1.0E-52 [7..306] [34..411]
gi|85077663 - gi|85077663|ref|XP_956039.1| hypothetical protein NCU01725 [Neurospora crassa OR74A]
gi|8218247, gi|3... - gi|8218247|emb|CAB92648.1| conserved hypothetical protein [Neurospora crassa], gi|32415369|ref|XP_32...
9.0E-50 [17..306] [27..398]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKKVNNPLK IDYQNGIIEN RLLQIRNFKD VNTPKLINVW SIRIDPRDSK KVIELIRNDF  60
   61 QKNDPVSLRH LKRIRKDIET STLEVVLCSK EYICDEGEIN NKLKSIWVGT KKYELSDDIE 120
  121 VPEFAPSTKE LNNAWSVKYW PLIWNGNPND QILNDYKID

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [160-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEVRNELSR ASTLSVKMAT AGKQFPMVSV FVDPSRKKDK VVAEDGRNCE NSLPIDHSVM  60
   61 VGIRAVGERL REGVDEDANS YLCLDYDVYL THEPCSMCSM ALIHSRVRRV VFLTEMQRTG 120
  121 SLKLTSGDGY CMNDNKQLNS TYEAFQWIGE EYPVGQVDRD VCC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1rb7A_
Description: Yeast cytosine deaminase crystal form p212121 with sodium acetate.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.70756445127105 bayes_pls_golite062009
binding 1.64474382695496 bayes_pls_golite062009
methyltransferase activity 1.24697538679504 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 1.16679252289538 bayes_pls_golite062009
transferase activity 0.771056210634777 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.113989053833271 bayes_pls_golite062009
protein binding 0.072557222523031 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle