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View Structure Prediction Details

Protein: TAD3
Organism: Saccharomyces cerevisiae
Length: 322 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAD3.

Description E-value Query
Range
Subject
Range
TAD3 - Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad2p that converts adenos...
TAD3_YEAST - tRNA-specific adenosine deaminase subunit TAD3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
1.0E-89 [1..322] [1..322]
gi|45199011, gi|... - gi|45199011|ref|NP_986040.1| AFR493Cp [Ashbya gossypii ATCC 10895], gi|44985086|gb|AAS53864.1| AFR49...
gi|44985086 - gi|44985086|gb|AAS53864.1| AFR493Cp [Ashbya gossypii ATCC 10895]
4.0E-73 [1..322] [1..324]
ADAT3_DANRE - Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Danio rerio GN=adat3 PE=2 SV=2
2.0E-58 [8..318] [3..336]
gi|68476669, gi|... - gi|68476816|ref|XP_717553.1| potential tRNA wobble position adenosine deaminase subunit [Candida alb...
orf19.12556, orf... - orf19.5090 CGDID:CAL0001811 Assembly 19, Contig19-10218 (79509, 80489) CDS, translated using codon t...
1.0E-54 [9..321] [6..321]
ADAT3_MOUSE - Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Mus musculus GN=Adat3 PE=1 SV=...
4.0E-54 [23..315] [29..345]
ADAT3 - adenosine deaminase, tRNA-specific 3, TAD3 homolog (S. cerevisiae)
2.0E-53 [23..313] [29..345]
gi|42545037, gi|... - gi|46109124|ref|XP_381620.1| hypothetical protein FG01444.1 [Gibberella zeae PH-1], gi|42545037|gb|E...
1.0E-52 [7..306] [34..411]
gi|85077663 - gi|85077663|ref|XP_956039.1| hypothetical protein NCU01725 [Neurospora crassa OR74A]
gi|8218247, gi|3... - gi|8218247|emb|CAB92648.1| conserved hypothetical protein [Neurospora crassa], gi|32415369|ref|XP_32...
9.0E-50 [17..306] [27..398]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKKVNNPLK IDYQNGIIEN RLLQIRNFKD VNTPKLINVW SIRIDPRDSK KVIELIRNDF  60
   61 QKNDPVSLRH LKRIRKDIET STLEVVLCSK EYICDEGEIN NKLKSIWVGT KKYELSDDIE 120
  121 VPEFAPSTKE LNNAWSVKYW PLIWNGNPND QILNDYKID

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [160-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEVRNELSR ASTLSVKMAT AGKQFPMVSV FVDPSRKKDK VVAEDGRNCE NSLPIDHSVM  60
   61 VGIRAVGERL REGVDEDANS YLCLDYDVYL THEPCSMCSM ALIHSRVRRV VFLTEMQRTG 120
  121 SLKLTSGDGY CMNDNKQLNS TYEAFQWIGE EYPVGQVDRD VCC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1rb7A_
Description: Yeast cytosine deaminase crystal form p212121 with sodium acetate.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.70756445127105 bayes_pls_golite062009
binding 1.64474382695496 bayes_pls_golite062009
methyltransferase activity 1.24697538679504 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 1.16679252289538 bayes_pls_golite062009
transferase activity 0.771056210634777 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.113989053833271 bayes_pls_golite062009
protein binding 0.072557222523031 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle