YRC Public Data Repository - Protein Structure Prediction

Protein:	CDA2
Organism:	Saccharomyces cerevisiae
Length:	312 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDA2.

Description	E-value	Query Range	Subject Range
CDA2 - Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chito... CDA2_YEAST - Chitin deacetylase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDA2 PE=1 SV=1	2.0E-87	[1..312]	[1..312]
gi\|27377137, gi\|... - gi\|27377137\|ref\|NP_768666.1\| de N-acatylase [Bradyrhizobium japonicum USDA 110], gi\|27350280\|dbj\|BAC... gi\|12620721 - gi\|12620721\|gb\|AAG60997.1\|AF322013_116 NodB [Bradyrhizobium japonicum]	1.0E-56	[110..300]	[13..218]
NODB_BRASP - Chitooligosaccharide deacetylase OS=Bradyrhizobium sp. (strain ANU 289) GN=nodB PE=3 SV=2 gi\|580896 - gi\|580896\|emb\|CAA27349.1\| unnamed protein product [Bradyrhizobium sp.]	1.0E-56	[105..300]	[8..218]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-56	[105..300]	[8..218]
gi\|595264 - gi\|595264\|gb\|AAA63601.1\| chitooligosaccharide deacetylase NODB_BRAEL - Chitooligosaccharide deacetylase OS=Bradyrhizobium elkanii GN=nodB PE=3 SV=1	3.0E-56	[110..300]	[13..218]
gi\|68271044 - gi\|68271044\|gb\|AAY89043.1\| NodB [Sinorhizobium fredii] NODB_RHISN - Chitooligosaccharide deacetylase OS=Rhizobium sp. (strain NGR234) GN=nodB PE=3 SV=2	2.0E-55	[105..299]	[5..213]
gi\|1531619 - gi\|1531619\|gb\|AAB16896.1\| NodB [Rhizobium sp. N33]	5.0E-55	[103..299]	[6..216]
NODB_RHILO - Chitooligosaccharide deacetylase OS=Rhizobium loti GN=nodB PE=3 SV=2 NODB_RHILO - Chitooligosaccharide deacetylase OS=Rhizobium loti (strain MAFF303099) GN=nodB PE=3 SV=2	1.0E-54	[112..299]	[15..217]
gi\|1405808 - gi\|1405808\|emb\|CAA67138.1\| nodB [Rhizobium tropici]	2.0E-54	[112..299]	[15..217]

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Predicted Domain #1

Region A:
Residues: [1-114]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIQLNTIDL QCIIALSCLG QFVHAEANRE DLKQIDFQFP VLERAATKTP FPDWLSAFTG  60
   61 LKEWPGLDPP YIPLDFIDFS QIPDYKEYDQ NHCDSVPRDS CSFDCHHCTE HDDV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.394	a.66.1	Transducin (alpha subunit), insertion domain
View	Download	0.336	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.331	a.45.1	Glutathione S-transferase (GST), C-terminal domain
View	Download	0.320	d.188.1	Prokaryotic ribosomal protein L17
View	Download	0.318	a.16.1	S15/NS1 RNA-binding domain
View	Download	0.301	a.1.1	Globin-like
View	Download	0.292	a.118.12	Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
View	Download	0.272	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.256	a.24.17	Group V grass pollen allergen
View	Download	0.228	a.7.3	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain

Predicted functions:

Term	Confidence	Notes
chitin deacetylase activity	10.7874217761055	bayes_pls_golite062009
deacetylase activity	5.05898534854944	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.02667023181984	bayes_pls_golite062009
binding	1.08589216404246	bayes_pls_golite062009
hydrolase activity	1.07980851332544	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	0.808382884321605	bayes_pls_golite062009
protein binding	0.394432087623352	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [115-312]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTCSKLSQTF DDGPSASTTK LLDRLKHNST FFNLGVNIVQ HPDIYQRMQK EGHLIGSHTW  60
   61 SHVYLPNVSN EKIIAQIEWS IWAMNATGNH TPKWFRPPYG GIDNRVRAIT RQFGLQAVLW 120
  121 DHDTFDWSLL LNDSVITEQE ILQNVINWNK SGTGLILEHD STEKTVDLAI KINKLIGDDQ 180
  181 STVSHCVGGI DYIKEFLS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	64.21467
Match:	PF01522
Description:	Polysaccharide deacetylase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: