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View Structure Prediction Details

Protein: ARV1
Organism: Saccharomyces cerevisiae
Length: 321 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARV1.

Description E-value Query
Range
Subject
Range
ARV1_YEAST - Protein ARV1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARV1 PE=1 SV=1
ARV1 - Protein functioning in transport of glycosylphosphatidylinositol intermediates into the ER lumen; re...
gi|151941078 - gi|151941078|gb|EDN59458.1| protein required for normal intracellular sterol distribution and for sp...
gi|207342911 - gi|207342911|gb|EDZ70534.1| YLR242Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190405304 - gi|190405304|gb|EDV08571.1| protein involved in sterol distribution [Saccharomyces cerevisiae RM11-1...
0.0 [1..321] [1..321]
gi|19114441 - gi|19114441|ref|NP_593529.1| hypothetical protein SPAPB1A10.15 [Schizosaccharomyces pombe 972h-]
SPAPB1A10.15 - Arv1-like family protein
6.0E-63 [1..262] [1..206]
gi|6715650 - gi|6715650|gb|AAF26477.1|AC007323_18 T25K16.2 [Arabidopsis thaliana]
5.0E-25 [3..81] [8..87]
gi|10439524 - gi|10439524|dbj|BAB15513.1| unnamed protein product [Homo sapiens]
9.0E-22 [3..68] [34..100]
ARV1_MOUSE - Protein ARV1 OS=Mus musculus GN=Arv1 PE=2 SV=1
2.0E-21 [3..68] [29..95]
gi|255674949, gi... - gi|34897126|ref|NP_909909.1| hypothetical protein [Oryza sativa], gi|255674949|dbj|BAF13386.2| Os03g...
2.0E-20 [28..117] [103..178]
CE02292 - status:Partially_confirmed UniProt:Q21765 protein_id:CAA88728.1
1.0E-17 [3..64] [22..83]
CG32442-PA - This gene is referred to in FlyBase by the symbol Dmel\CG32442 (CG32442, FBgn0052442). It is a prote...
gi|220948670, gi... - gi|220958074|gb|ACL91580.1| CG32442-PA [synthetic construct], gi|220948670|gb|ACL86878.1| CG32442-PA...
1.0E-17 [2..63] [8..68]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MICITCMRPV DSLYTVYSND HIQLTDCPYC QETVDKYVEI DNVLLFIDLL LLKAGAYRHL  60
   61 VFNALELHLS KYPKRKALND CQCLRDYTQA LLFNVKNWFC KYDRLNRLWL LLLSFEIYLT 120
  121 WVTEESKYIY YLNRN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.700 0.831 sterol metabolic process a.26.1 4-helical cytokines

Predicted functions:

Term Confidence Notes
binding 1.84624717401156 bayes_pls_golite062009
protein binding 1.70162902007087 bayes_pls_golite062009
transporter activity 1.30067041733468 bayes_pls_golite062009
receptor activity 1.27081218639227 bayes_pls_golite062009
transcription regulator activity 1.1514442454341 bayes_pls_golite062009
nucleic acid binding 1.15037818154029 bayes_pls_golite062009
transmembrane transporter activity 1.07971596062462 bayes_pls_golite062009
DNA binding 1.07906220177233 bayes_pls_golite062009
substrate-specific transporter activity 0.809838091223165 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.555014154605011 bayes_pls_golite062009
transcription factor activity 0.4825638884734 bayes_pls_golite062009
ion transmembrane transporter activity 0.253562998805943 bayes_pls_golite062009
signal transducer activity 0.212488443103452 bayes_pls_golite062009
molecular transducer activity 0.212488443103452 bayes_pls_golite062009
catalytic activity 0.133319360419662 bayes_pls_golite062009
structural constituent of ribosome 0.0849070471490733 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [136-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNDGKLIMLS KKLPESFKWD SAIMRNTITS KVFTWSPPIQ YLYFASYCIL DVSLFHTFTQ  60
   61 YFILKKLHWK HYSVSSKDVI SYTILLSYGA KIFPILMLIW PYDTLISMSI IKWVANLYII 120
  121 ESLKIVTNLS YWNIIKIFIS VSLLRYFMVK PILIVFVAKF NFSVIKNLIH QEFILLLQKS 180
  181 GTYLLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.552 0.839 sterol metabolic process a.26.1 4-helical cytokines

Predicted Domain #3
Region A:
Residues: [162-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TITSKVFTWS PPIQYLYFAS YCILDVSLFH TFTQYFILKK LHWKHYSVSS KDVISYTILL  60
   61 SYGAKIFPIL MLIWPYDTLI SMSIIKWVAN LYIIESLKIV TNLSYWNIIK IFISVSLLRY 120
  121 FMVKPILIVF VAKFNFSVIK NLIHQEFILL LQKSGTYLLL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle