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View Structure Prediction Details

Protein: GAA1
Organism: Saccharomyces cerevisiae
Length: 614 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAA1.

Description E-value Query
Range
Subject
Range
GAA1 - Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anch...
GAA1_YEAST - GPI transamidase component GAA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAA1 PE=...
gi|151941255 - gi|151941255|gb|EDN59633.1| GPI anchor attachment-related protein [Saccharomyces cerevisiae YJM789]
0.0 [1..614] [1..614]
CG3033-PA - This gene is referred to in FlyBase by the symbol Dmel\CG3033 (CG3033, FBgn0029818). It is a protein...
0.0 [1..603] [1..648]
GPAA1_MOUSE - Glycosylphosphatidylinositol anchor attachment 1 protein OS=Mus musculus GN=Gpaa1 PE=1 SV=3
0.0 [1..481] [1..530]
GPAA1 - glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)
gi|123996727, gi... - gi|157928956|gb|ABW03763.1| glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)...
0.0 [1..481] [1..530]
gaa1 - GPI-anchor transamidase complex subunit Gaa1
GAA1_SCHPO - GPI transamidase component gaa1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gaa1 PE=3 ...
0.0 [12..485] [7..493]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [9..442] [291..758]

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Predicted Domain #1
Region A:
Residues: [1-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLEKLHRR IVDMGLVPRI IALLPVISML CALFGFISIA ILPMDGQYRR TYISENALMP  60
   61 SQAYSYFRES EWNILRGYRS QIKEMVNMTS MERNNLMGSW LQEFGTKTAI YENEQYGETL 120
  121 YGVMHAPRGD GTEAMVLAVP WFNSDDEFNI GGAALGVSLA RFFSRWPVWS KNIIVVFSEN 180
  181 PRAALRSWVE AYHTSLDLTG GSIEAAVVLD YSSTEDFFEY VEISYDGLNG ELPNLDLVNI 240
  241 AISITEHEGM KVSLHGLPSD QLTNNNFWSR LKILCLGIRD WALSGVKKPH GNEAFSGWRI 300
  301 QSVTLKAHG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
hydrolase activity 1.72000211894151 bayes_pls_golite062009
catalytic activity 1.30073863026596 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.04545175523841 bayes_pls_golite062009
binding 0.768831715417683 bayes_pls_golite062009
peptidase activity 0.700635398774672 bayes_pls_golite062009
nucleic acid binding 0.362145256746391 bayes_pls_golite062009
metallopeptidase activity 0.177551285129758 bayes_pls_golite062009
transcription regulator activity 0.171364523459 bayes_pls_golite062009
DNA binding 0.0535456396545306 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [310-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSGHDITTFG RIPEAMFRSI NNLLEKFHQS FFFYLLLAPR QFVSISSYLP SAVALSIAFA  60
   61 ISSLNAFINN AYANISLFSE YNLVALLVWF VSLVISFVVS QAFLLIPSSG LLMTISMASC 120
  121 FLPLILSRKI HISEPLSYRL KNVAFLYFSL VSTSLLMINF AMALLIGTLA FPMTFVKTIV 180
  181 ESSSEHEVTT QSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [503-614]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPIKTEPKDE IELVENHMDT TPATPQQQKQ KLKNLVLLIL TNPFISITLF GLFFDDEFHG  60
   61 FDIINKLVSA WLDLKCWSWF VLCIGWLPCW LLILASSFES KSVVVRSKEK QS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle