| Protein: | GAA1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 614 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAA1.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..614] | [1..614] |
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|
0.0 | [1..603] | [1..648] |
|
|
0.0 | [1..481] | [1..530] |
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0.0 | [1..481] | [1..530] |
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0.0 | [12..485] | [7..493] |
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|
0.0 | [9..442] | [291..758] |
|
Region A: Residues: [1-309] |
1 11 21 31 41 51
| | | | | |
1 MALLEKLHRR IVDMGLVPRI IALLPVISML CALFGFISIA ILPMDGQYRR TYISENALMP 60
61 SQAYSYFRES EWNILRGYRS QIKEMVNMTS MERNNLMGSW LQEFGTKTAI YENEQYGETL 120
121 YGVMHAPRGD GTEAMVLAVP WFNSDDEFNI GGAALGVSLA RFFSRWPVWS KNIIVVFSEN 180
181 PRAALRSWVE AYHTSLDLTG GSIEAAVVLD YSSTEDFFEY VEISYDGLNG ELPNLDLVNI 240
241 AISITEHEGM KVSLHGLPSD QLTNNNFWSR LKILCLGIRD WALSGVKKPH GNEAFSGWRI 300
301 QSVTLKAHG
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| hydrolase activity | 1.72000211894151 | bayes_pls_golite062009 |
| catalytic activity | 1.30073863026596 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 1.04545175523841 | bayes_pls_golite062009 |
| binding | 0.768831715417683 | bayes_pls_golite062009 |
| peptidase activity | 0.700635398774672 | bayes_pls_golite062009 |
| nucleic acid binding | 0.362145256746391 | bayes_pls_golite062009 |
| metallopeptidase activity | 0.177551285129758 | bayes_pls_golite062009 |
| transcription regulator activity | 0.171364523459 | bayes_pls_golite062009 |
| DNA binding | 0.0535456396545306 | bayes_pls_golite062009 |
|
Region A: Residues: [310-502] |
1 11 21 31 41 51
| | | | | |
1 NSGHDITTFG RIPEAMFRSI NNLLEKFHQS FFFYLLLAPR QFVSISSYLP SAVALSIAFA 60
61 ISSLNAFINN AYANISLFSE YNLVALLVWF VSLVISFVVS QAFLLIPSSG LLMTISMASC 120
121 FLPLILSRKI HISEPLSYRL KNVAFLYFSL VSTSLLMINF AMALLIGTLA FPMTFVKTIV 180
181 ESSSEHEVTT QSS
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.318 | 0.222 | integral to endoplasmic reticulum membrane | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.359 | 0.029 | integral to endoplasmic reticulum membrane | a.47.2 | t-snare proteins |
| View | Download | 0.350 | 0.019 | integral to endoplasmic reticulum membrane | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.359 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.352 | N/A | N/A | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.352 | N/A | N/A | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.350 | N/A | N/A | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.323 | N/A | N/A | f.21.1 | Transmembrane di-heme cytochromes |
| View | Download | 0.323 | N/A | N/A | f.21.1 | Transmembrane di-heme cytochromes |
| View | Download | 0.318 | N/A | N/A | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.317 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.293 | N/A | N/A | a.118.7 | 14-3-3 protein |
| View | Download | 0.279 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.255 | N/A | N/A | a.166.1 | RuBisCo LSMT C-terminal, substrate-binding domain |
| View | Download | 0.239 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.236 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.235 | N/A | N/A | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.234 | N/A | N/A | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.223 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.208 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.206 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.204 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.203 | N/A | N/A | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.201 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
|
Region A: Residues: [503-614] |
1 11 21 31 41 51
| | | | | |
1 NPIKTEPKDE IELVENHMDT TPATPQQQKQ KLKNLVLLIL TNPFISITLF GLFFDDEFHG 60
61 FDIINKLVSA WLDLKCWSWF VLCIGWLPCW LLILASSFES KSVVVRSKEK QS
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.484 | b.1.1 | Immunoglobulin |
| View | Download | 0.488 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.625 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.556 | a.46.1 | Methionine synthase domain |
| View | Download | 0.625 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.572 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.572 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.556 | a.46.1 | Methionine synthase domain |
| View | Download | 0.488 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.484 | b.1.1 | Immunoglobulin |
| View | Download | 0.476 | a.1.1 | Globin-like |
| View | Download | 0.455 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.448 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.444 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.439 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.437 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.437 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.435 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.433 | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.426 | a.158.1 | F-box domain |
| View | Download | 0.424 | d.58.27 | Translational regulator protein regA |
| View | Download | 0.423 | a.39.1 | EF-hand |
| View | Download | 0.421 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.420 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.416 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.414 | a.74.1 | Cyclin-like |
| View | Download | 0.412 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.406 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.406 | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.396 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.389 | a.74.1 | Cyclin-like |
| View | Download | 0.381 | d.2.1 | Lysozyme-like |
| View | Download | 0.367 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.364 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.352 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.351 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.350 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.345 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.344 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.340 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.339 | a.118.1 | ARM repeat |
| View | Download | 0.328 | a.118.13 | Arp2/3 complex 16 kDa subunit ARPC5 |
| View | Download | 0.328 | d.2.1 | Lysozyme-like |
| View | Download | 0.324 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.321 | b.1.18 | E set domains |
| View | Download | 0.310 | a.118.9 | ENTH/VHS domain |
| View | Download | 0.309 | a.66.1 | Transducin (alpha subunit), insertion domain |
| View | Download | 0.304 | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.298 | d.58.14 | Ribosomal protein S6 |
| View | Download | 0.293 | d.15.4 | 2Fe-2S ferredoxin-like |
| View | Download | 0.288 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.285 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.277 | a.1.1 | Globin-like |
| View | Download | 0.272 | a.47.2 | t-snare proteins |
| View | Download | 0.268 | d.21.1 | Diaminopimelate epimerase-like |
| View | Download | 0.260 | a.7.1 | Spectrin repeat |
| View | Download | 0.259 | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.253 | a.1.1 | Globin-like |
| View | Download | 0.250 | a.39.1 | EF-hand |
| View | Download | 0.245 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.242 | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.240 | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.239 | d.118.1 | N-acetylmuramoyl-L-alanine amidase-like |
| View | Download | 0.237 | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.235 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.234 | a.4.3 | ARID-like |
| View | Download | 0.231 | a.74.1 | Cyclin-like |
| View | Download | 0.229 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.227 | a.26.1 | 4-helical cytokines |
| View | Download | 0.223 | a.1.1 | Globin-like |
| View | Download | 0.223 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.222 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.222 | a.39.1 | EF-hand |
| View | Download | 0.222 | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.221 | d.17.4 | NTF2-like |
| View | Download | 0.219 | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.213 | a.74.1 | Cyclin-like |
| View | Download | 0.211 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.206 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.201 | a.3.1 | Cytochrome c |
