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View Structure Prediction Details

Protein: BCH2
Organism: Saccharomyces cerevisiae
Length: 765 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BCH2.

Description E-value Query
Range
Subject
Range
BCH2 - Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), t...
BCH2_YEAST - Protein BCH2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BCH2 PE=1 SV=1
0.0 [1..765] [1..765]
gi|6179405 - gi|6179405|emb|CAB59913.1| hypothetical protein [Candida albicans]
0.0 [44..717] [15..712]
SPBC31F10.16 - ChAPs family protein
YB2G_SCHPO - Uncharacterized protein C31F10.16 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC31F1...
0.0 [40..408] [6..372]
gi|6474345 - gi|6474345|dbj|BAA87246.1| Hypothetical nuclear protein [Schizosaccharomyces pombe]
6.0E-54 [220..408] [4..166]

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Predicted Domain #1
Region A:
Residues: [1-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFLWGSTKS KKGKNKKAAG SLPSGVVPQQ RVKPTRKNVP IDYPRTLEKV HGESLIFRTS  60
   61 LLSELVSTGK SGIGPPDLIH CTELDKFHDE KIGEFFYITG IDASSVSMPI AFLKLIKWND 120
  121 GKKLKSASLK NDDITTYCTF NIFQKLDIRL RYESEDVYQV NIVDCLNGNN EIPLSDLIWE 180
  181 ETFVSCCIRS VIINSDFERK IPGLVELPFV FENRCASDYK RVIDSLCKFL PRFLECGWDS 240
  241 TKSVYATILN NYLTESLLVF LSITPEFITD YAIQVLDNLM TNDPSNSRYY AIVIISIMER 300
  301 SNDRDVEMIK RIHEILDLLL PVLYGLPSDE PYISDLINCI TDVLSIQARF LLNNNDYELS 360
  361 LSISTLATNL SSDNFESWYL LSKGYIFSQQ YDKALLSINS MPCLAEYDIV KQAQINAFK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
drug binding 1.97908029685084 bayes_pls_golite062009
isomerase activity 1.19192091517095 bayes_pls_golite062009
catalytic activity 0.838457647933563 bayes_pls_golite062009
peptidyl-prolyl cis-trans isomerase activity 0.788209490718562 bayes_pls_golite062009
transporter activity 0.741927397485699 bayes_pls_golite062009
cis-trans isomerase activity 0.728844238348547 bayes_pls_golite062009
transcription regulator activity 0.68050479178453 bayes_pls_golite062009
binding 0.647093863277037 bayes_pls_golite062009
transmembrane transporter activity 0.489382802264305 bayes_pls_golite062009
protein binding 0.480005676233146 bayes_pls_golite062009
substrate-specific transporter activity 0.18557772671331 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [420-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYMNYYKAPL CHSREHCTMT SHELNHLMNI MHYENELELK TIIFGRTVMP NESKYGCIEE  60
   61 IWNKSCLELG PICGPQSDNL INFVSQQEVN TVG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [513-765]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMLLLKRSKE TRQESWFIKQ VRLLLMELVA RIGWNALLQL RSDVFVMESK FKMIESSDKL  60
   61 STELRQKRLC QRWFDAMFLD VYEDLSISTS SQENKATAKY SGLEWELLGL TLLRVSDLPD 120
  121 AVACLRTSIL ARFDPISCHH LLNFYLTMDF NDEFMRRFDV DIILDLLVKL ISFRIRFYDR 180
  181 FQIFSLQVLR KLEGQLGSEI IKNKIINSPY GQAGITSVID YMLECLSKNR NEACLAYERP 240
  241 LPDLPSTIKP LAD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle