YRC Public Data Repository - Protein Structure Prediction

Protein:	YKL187C
Organism:	Saccharomyces cerevisiae
Length:	750 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL187C.

Description	E-value	Query Range	Subject Range
YKS7_YEAST - Uncharacterized protein YKL187C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YKL187C ... YKL187C - Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphoryla...	0.0	[1..750]	[1..750]
gi\|164426759, gi... - gi\|164426759\|ref\|XP_961328.2\| hypothetical protein NCU03601 [Neurospora crassa OR74A], gi\|157071466\|... gi\|18376388 - gi\|18376388\|emb\|CAD21277.1\| conserved hypothetical protein [Neurospora crassa]	8.0E-4	[442..641]	[98..283]
gi\|293690, gi\|33... - gi\|33859490\|ref\|NP_032508.1\| laminin B1 subunit 1 [Mus musculus], gi\|293690\|gb\|AAA39407.1\| laminin B...	9.0E-4	[196..360]	[1525..1696]
gi\|55742055 - ref\|NP_001007209.1\| coagulation factor V [Danio rerio] gi\|55742055, gi\|... - gi\|55742055\|ref\|NP_001007209.1\| coagulation factor V [Danio rerio], gi\|16200178\|emb\|CAC94896.1\| nove...	0.003	[88..357]	[1006..1246]
gi\|6164595 - gi\|6164595\|gb\|AAF04457.1\|AF078161_1 lacunin [Manduca sexta]	0.005	[97..358]	[1240..1504]
gi\|7515889 - pir\|\|C72647 hypothetical protein APE0609 - Aeropyrum pernix (strain K1) gi\|5104264, gi\|1... - gi\|5104264\|dbj\|BAA79579.1\| 1554aa long hypothetical protein [Aeropyrum pernix K1], gi\|14600835\|ref\|N...	0.008	[57..386]	[1168..1511]

Back

Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIEKHRTPL SKGIIWTILS VCLLFMFTTL ILVIVATAGS TANYKPLTNI YIGEADIKHI  60
   61 NVSKVIPQIG PILTILGSAL TAPNSSLDDI FGAMKNIADT PALTPLLTLL SNADNTTVTI 120
  121 ESLTELAPLA ISGNPASSTR QLTEINGLLK YSDNATETLD GLSRLVSASL SSASSNSS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [179-367]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDSTTLVLDL LKDSDNPQNS TDALLTLNNL TMSEKAQLLP VFRLFAFSTN QTATMTALAT  60
   61 LMNTTISSSL AQTLLTQLQN TISNGGSLNN TFSTLQPLVP QASAPAFDAV ELLLNQTTST 120
  121 NQTLSTLSDL LEQNLTQSSS AKKAFAALTQ LMENSDNSTM VVTSVQSLAA VTNTTQSTQQ 180
  181 LIGLDDVIS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	0.0786210554855438	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [368-441]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSNTNETLS ILSELQSGLS GNSSSVQYIP YLFSLLGAST DPKTTFSSLV TLTSWAQENP  60
   61 QTFLPILDIL ADAK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.846	0.003	mitochondrion	a.24.13	Domain of the SRP/SRP receptor G-proteins

Predicted Domain #4

Region A:
Residues: [442-689]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVQPISAEEL NAMTPNILEY LKIPIYYRLS IFTLCHANLE NKILDCNSPH AVQNLDFRSI  60
   61 IYDALVTSDF QPYLNALNIS ANDLYLEGKL LHREHQYVPA VRSVLALNLL AIIFSFFTMI 120
  121 FIILLYFNRY MFKQPLWLIA LALHVCVGVA TVLAAIIISV MIAIIKSGTA DDKYGVVFKA 180
  181 GPAYTGLIWT AFALSFIATG LIIYTWWRNR RSGRYMSGSV TNRKGEIYTY GDGSAISADR 240
  241 FGDHNLGD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [690-750]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDADFEKQV NRNEITAIDN SSSANNTDVT GSTSNRTELS HPDVTPKDSN GPVNNNAHLV  60
   61 A

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: