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View Structure Prediction Details

Protein: YKL187C
Organism: Saccharomyces cerevisiae
Length: 750 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL187C.

Description E-value Query
Range
Subject
Range
YKS7_YEAST - Uncharacterized protein YKL187C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YKL187C ...
YKL187C - Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphoryla...
0.0 [1..750] [1..750]
gi|164426759, gi... - gi|164426759|ref|XP_961328.2| hypothetical protein NCU03601 [Neurospora crassa OR74A], gi|157071466|...
gi|18376388 - gi|18376388|emb|CAD21277.1| conserved hypothetical protein [Neurospora crassa]
8.0E-4 [442..641] [98..283]
gi|293690, gi|33... - gi|33859490|ref|NP_032508.1| laminin B1 subunit 1 [Mus musculus], gi|293690|gb|AAA39407.1| laminin B...
9.0E-4 [196..360] [1525..1696]
gi|55742055 - ref|NP_001007209.1| coagulation factor V [Danio rerio]
gi|55742055, gi|... - gi|55742055|ref|NP_001007209.1| coagulation factor V [Danio rerio], gi|16200178|emb|CAC94896.1| nove...
0.003 [88..357] [1006..1246]
gi|6164595 - gi|6164595|gb|AAF04457.1|AF078161_1 lacunin [Manduca sexta]
0.005 [97..358] [1240..1504]
gi|7515889 - pir||C72647 hypothetical protein APE0609 - Aeropyrum pernix (strain K1)
gi|5104264, gi|1... - gi|5104264|dbj|BAA79579.1| 1554aa long hypothetical protein [Aeropyrum pernix K1], gi|14600835|ref|N...
0.008 [57..386] [1168..1511]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIEKHRTPL SKGIIWTILS VCLLFMFTTL ILVIVATAGS TANYKPLTNI YIGEADIKHI  60
   61 NVSKVIPQIG PILTILGSAL TAPNSSLDDI FGAMKNIADT PALTPLLTLL SNADNTTVTI 120
  121 ESLTELAPLA ISGNPASSTR QLTEINGLLK YSDNATETLD GLSRLVSASL SSASSNSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [179-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDSTTLVLDL LKDSDNPQNS TDALLTLNNL TMSEKAQLLP VFRLFAFSTN QTATMTALAT  60
   61 LMNTTISSSL AQTLLTQLQN TISNGGSLNN TFSTLQPLVP QASAPAFDAV ELLLNQTTST 120
  121 NQTLSTLSDL LEQNLTQSSS AKKAFAALTQ LMENSDNSTM VVTSVQSLAA VTNTTQSTQQ 180
  181 LIGLDDVIS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.0786210554855438 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [368-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSNTNETLS ILSELQSGLS GNSSSVQYIP YLFSLLGAST DPKTTFSSLV TLTSWAQENP  60
   61 QTFLPILDIL ADAK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.846 0.003 mitochondrion a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.783 0.003 mitochondrion a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.782 0.003 mitochondrion a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.646 0.003 mitochondrion a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.646 0.003 mitochondrion a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.627 0.003 mitochondrion a.60.9 lambda integrase-like, N-terminal domain
View Download 0.623 0.003 mitochondrion a.17.1 p8-MTCP1
View Download 0.601 0.003 mitochondrion a.4.5 "Winged helix" DNA-binding domain
View Download 0.591 0.003 mitochondrion a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.591 0.003 mitochondrion a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.578 0.003 mitochondrion a.61.1 Retroviral matrix proteins
View Download 0.508 0.003 mitochondrion a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.506 0.003 mitochondrion a.65.1 Annexin
View Download 0.502 0.003 mitochondrion a.4.5 "Winged helix" DNA-binding domain
View Download 0.496 0.003 mitochondrion a.4.5 "Winged helix" DNA-binding domain
View Download 0.492 0.003 mitochondrion a.144.1 PABC (PABP) domain
View Download 0.480 0.003 mitochondrion a.74.1 Cyclin-like
View Download 0.456 0.003 mitochondrion a.4.5 "Winged helix" DNA-binding domain
View Download 0.454 0.003 mitochondrion a.5.6 Hypothetical protein MTH1615
View Download 0.448 0.003 mitochondrion a.60.13 Putative methyltransferase TM0872, insert domain
View Download 0.440 0.003 mitochondrion a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.435 0.003 mitochondrion a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.424 0.003 mitochondrion a.74.1 Cyclin-like
View Download 0.421 0.003 mitochondrion a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.404 0.003 mitochondrion a.4.1 Homeodomain-like
View Download 0.398 0.003 mitochondrion a.7.6 Ribosomal protein S20
View Download 0.397 0.003 mitochondrion a.118.9 ENTH/VHS domain
View Download 0.395 0.003 mitochondrion a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.393 0.003 mitochondrion a.150.1 Anti-sigma factor AsiA
View Download 0.392 0.003 mitochondrion a.4.12 TrpR-like
View Download 0.384 0.003 mitochondrion a.4.1 Homeodomain-like
View Download 0.376 0.003 mitochondrion d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.374 0.003 mitochondrion a.4.1 Homeodomain-like
View Download 0.369 0.003 mitochondrion a.39.1 EF-hand
View Download 0.365 0.003 mitochondrion a.4.1 Homeodomain-like
View Download 0.364 0.003 mitochondrion a.39.1 EF-hand
View Download 0.358 0.003 mitochondrion a.60.8 HRDC-like
View Download 0.358 0.003 mitochondrion f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.349 0.003 mitochondrion a.5.2 UBA-like
View Download 0.347 0.003 mitochondrion a.112.1 Description not found.
View Download 0.345 0.003 mitochondrion d.39.1 Dynein light chain 8 (DLC8)
View Download 0.336 0.003 mitochondrion d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.330 0.003 mitochondrion a.159.2 FF domain
View Download 0.326 0.003 mitochondrion a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.326 0.003 mitochondrion d.8.1 Urease, gamma-subunit
View Download 0.320 0.003 mitochondrion a.64.2 Bacteriocin AS-48
View Download 0.318 0.003 mitochondrion a.24.17 Group V grass pollen allergen
View Download 0.311 0.003 mitochondrion a.39.1 EF-hand
View Download 0.310 0.003 mitochondrion a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.305 0.003 mitochondrion a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.303 0.003 mitochondrion a.74.1 Cyclin-like
View Download 0.303 0.003 mitochondrion a.7.7 BAG domain
View Download 0.303 0.003 mitochondrion a.24.17 Group V grass pollen allergen
View Download 0.301 0.003 mitochondrion a.60.1 SAM/Pointed domain
View Download 0.299 0.003 mitochondrion a.24.3 Cytochromes
View Download 0.295 0.003 mitochondrion a.60.11 Hypothetical protein YjbJ
View Download 0.290 0.003 mitochondrion a.39.1 EF-hand
View Download 0.288 0.003 mitochondrion a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.285 0.003 mitochondrion a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.284 0.003 mitochondrion a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.284 0.003 mitochondrion a.35.1 lambda repressor-like DNA-binding domains
View Download 0.284 0.003 mitochondrion c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.281 0.003 mitochondrion a.77.1 DEATH domain
View Download 0.279 0.003 mitochondrion a.91.1 Regulator of G-protein signalling, RGS
View Download 0.278 0.003 mitochondrion a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.278 0.003 mitochondrion a.29.4 RecG, N-terminal domain
View Download 0.275 0.003 mitochondrion a.23.5 Hemolysin expression modulating protein HHA
View Download 0.271 0.003 mitochondrion a.118.9 ENTH/VHS domain
View Download 0.270 0.003 mitochondrion a.85.1 Hemocyanin, N-terminal domain
View Download 0.268 0.003 mitochondrion a.60.1 SAM/Pointed domain
View Download 0.267 0.003 mitochondrion a.81.1 N-terminal domain of DnaB helicase
View Download 0.266 0.003 mitochondrion a.118.8 TPR-like
View Download 0.263 0.003 mitochondrion a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.262 0.003 mitochondrion a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.258 0.003 mitochondrion a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.257 0.003 mitochondrion e.40.1 Cullin homology domain
View Download 0.255 0.003 mitochondrion a.21.1 HMG-box
View Download 0.240 0.003 mitochondrion a.2.7 tRNA-binding arm
View Download 0.240 0.003 mitochondrion a.101.1 Uteroglobin-like
View Download 0.237 0.003 mitochondrion i.11.1 Computational models partly based on NMR data
View Download 0.235 0.003 mitochondrion a.28.1 ACP-like
View Download 0.233 0.003 mitochondrion a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.231 0.003 mitochondrion d.42.1 POZ domain
View Download 0.229 0.003 mitochondrion a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.229 0.003 mitochondrion a.59.1 PAH2 domain
View Download 0.218 0.003 mitochondrion d.50.3 PI-Pfui intein middle domain
View Download 0.218 0.003 mitochondrion a.28.2 Colicin E immunity proteins
View Download 0.214 0.003 mitochondrion a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.212 0.003 mitochondrion a.60.12 DNA polymerase beta-like, second domain
View Download 0.212 0.003 mitochondrion a.2.3 Chaperone J-domain
View Download 0.212 0.003 mitochondrion a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.211 0.003 mitochondrion a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.210 0.003 mitochondrion d.56.1 GroEL-intermediate domain like
View Download 0.208 0.003 mitochondrion a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.208 0.003 mitochondrion a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.206 0.003 mitochondrion a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.201 0.003 mitochondrion a.24.15 FAD-dependent thiol oxidase
View Download 0.201 0.003 mitochondrion a.35.1 lambda repressor-like DNA-binding domains

Predicted Domain #4
Region A:
Residues: [442-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVQPISAEEL NAMTPNILEY LKIPIYYRLS IFTLCHANLE NKILDCNSPH AVQNLDFRSI  60
   61 IYDALVTSDF QPYLNALNIS ANDLYLEGKL LHREHQYVPA VRSVLALNLL AIIFSFFTMI 120
  121 FIILLYFNRY MFKQPLWLIA LALHVCVGVA TVLAAIIISV MIAIIKSGTA DDKYGVVFKA 180
  181 GPAYTGLIWT AFALSFIATG LIIYTWWRNR RSGRYMSGSV TNRKGEIYTY GDGSAISADR 240
  241 FGDHNLGD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [690-750]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDADFEKQV NRNEITAIDN SSSANNTDVT GSTSNRTELS HPDVTPKDSN GPVNNNAHLV  60
   61 A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.298 a.4.5 "Winged helix" DNA-binding domain
View Download 0.278 b.38.1 Sm-like ribonucleoproteins
View Download 0.386 d.10.1 DNA-binding domain
View Download 0.486 a.144.2 Ribosomal protein L20
View Download 0.335 d.58.24 CheY-binding domain of CheA
View Download 0.225 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.210 a.60.4 DNA repair protein Rad51, N-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle