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View Structure Prediction Details

Protein: RGT1
Organism: Saccharomyces cerevisiae
Length: 1170 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RGT1.

Description E-value Query
Range
Subject
Range
RGT1_YEAST - Glucose transport transcription regulator RGT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
RGT1 - Glucose-responsive transcription factor that regulates expression of several glucose transporter (HX...
RGT1_YEAS1 - Glucose transport transcription regulator RGT1 OS=Saccharomyces cerevisiae (strain RM11-1a) GN=RGT1 ...
0.0 [1..1170] [1..1170]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
8.0E-59 [3..505] [599..1091]
gi|15277229 - gi|15277229|dbj|BAB63322.1| KIAA0170 [Homo sapiens]
3.0E-51 [7..509] [1040..1598]
XLNR_ASPFN - Xylanolytic transcriptional activator xlnR OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / ...
XLNR_ASPOR - Xylanolytic transcriptional activator xlnR OS=Aspergillus oryzae GN=xlnR PE=1 SV=2
XLNR_ASPOR - Xylanolytic transcriptional activator xlnR OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) GN=xln...
1.0E-46 [4..370] [81..429]
XLNR_ASPNG - Transcriptional activator xlnR OS=Aspergillus niger GN=xlnR PE=4 SV=1
2.0E-43 [5..351] [6..314]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNELNTVSTN SSDSTKNGGT SNSPDDMDSA AAASHAIKKR TKASRACDQC RKKKIKCDYK  60
   61 DEKGVCSNCQ RNGDRCSFDR VPLKRGPSKG YTRSTSHPRT NEIQDHNNSR SYNTFDNSNN 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 1hwtC_
Description: Hap1 (Cyp1); HAP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 3.86871420827942 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.03201524223606 bayes_pls_golite062009
sequence-specific DNA binding 1.87955444697212 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.86200506906385 bayes_pls_golite062009
transcription activator activity 0.915626626047549 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [121-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLNNNTGNSG DNGINSNTVP STPSRSNSVL LPPLTQYIPQ AGGIPPSFQN PAIQSTMPAG  60
   61 NIGQQQFWKV PYHEFQHQRK GSIDSLQSDI SVRTLNPNEQ LSYNTVQQSP ITNKHTNDSG 120
  121 NANGSVTGSG SASGSGGYWS FIRTSGLLAP TDDHNGEQTR RSSSIPSLLR NTSNSLLLGG 180
  181 QPQLPPPQQQ SQPQAHQQKL QQGQNLYSYS QFSQQQPYNP SISSFGQFAA NGFHSRQGSV 240
  241 ASEAMSPSAP AMFTSTSTNP VNVAQQTQRP QGQQVPQFSS ELDGNKRRQS APVSVTLSTD 300
  301 RLNGNENNNG EINNNNGSNN SGSSKDTSQH SQESVTTPAA LEASSPGSTP 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [471-1170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRSTKKRRKS YVSKKTKPKR DSSISITSKD SAHPMTTSST IAYGQISDVD LIDTYYEFIH  60
   61 VGFPIIPLNK TTLTSDLLLV NTQPISNIHE VNSYVILWFR NSLELLVRVA LKQKPGGKFF 120
  121 DNIVGVALSP SNDNNKAGFT TATARDDAEK TRRDSHNEVQ DTLEVQSVFI AALNECFQKI 180
  181 VDIHPKFREN NDQISPKIKV IYLSTFILLN YILAFVGYDN SFVLGMSVTI FNEFKLYKLL 240
  241 LFPEPDINDV KPPVDEEVST GNGNTKTSEF EIGSESAGHM NPSNSPNSMD ENISHYSVLF 300
  301 KRLYVLLSVF DSLQSCAFGG PKLLNISIQG STERFFSNDL GSKWCLEQSQ LRLKSVLQSL 360
  361 KLGELMSELT RNRISMNGNR KPGFDITNSS SLLSEYVETQ PLSVAQLFCK LLIGKHNFIN 420
  421 CLLSLYDSEA GVYSDLTLDL SSKIADSLCS LISIILQVLT LILRLNPTNS IDFNYRPPNP 480
  481 PANNPTVQEG PSAMGSSPVA GNLSAAPPSE GNPDFYKKLL GLKQDTGTIL SDLCRGIISP 540
  541 FAIAILHEVY NITELVKQMP TSLISIMMTA TTTQNTQDTK KSQDLVMKLS NSMNEVVQIT 600
  601 SVLTMIKPFK IFEHELNKPI MSLTGGLSST TRNDVMWPKS GQGLRESSVM KTLLDERRTS 660
  661 GTQPTTAPVA AEEPRLENVA LENFVSIGWK LLDDSELGWY 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [458-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAALEASSPG STPQRSTKKR RKSYVSKKTK PKRDSSISIT SKDSAHPMTT SSTIAYGQIS  60
   61 DVDLIDTYYE FIHVGFPIIP LNKTTLTSDL LLVNTQPISN IHEVNSYVIL WFRNSLELLV 120
  121 RVALKQKPGG KFFDNIVGVA LSPSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [603-722]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNNKAGFTTA TARDDAEKTR RDSHNEVQDT LEVQSVFIAA LNECFQKIVD IHPKFRENND  60
   61 QISPKIKVIY LSTFILLNYI LAFVGYDNSF VLGMSVTIFN EFKLYKLLLF PEPDINDVKP 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [723-976]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVDEEVSTGN GNTKTSEFEI GSESAGHMNP SNSPNSMDEN ISHYSVLFKR LYVLLSVFDS  60
   61 LQSCAFGGPK LLNISIQGST ERFFSNDLGS KWCLEQSQLR LKSVLQSLKL GELMSELTRN 120
  121 RISMNGNRKP GFDITNSSSL LSEYVETQPL SVAQLFCKLL IGKHNFINCL LSLYDSEAGV 180
  181 YSDLTLDLSS KIADSLCSLI SIILQVLTLI LRLNPTNSID FNYRPPNPPA NNPTVQEGPS 240
  241 AMGSSPVAGN LSAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [977-1170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSEGNPDFY KKLLGLKQDT GTILSDLCRG IISPFAIAIL HEVYNITELV KQMPTSLISI  60
   61 MMTATTTQNT QDTKKSQDLV MKLSNSMNEV VQITSVLTMI KPFKIFEHEL NKPIMSLTGG 120
  121 LSSTTRNDVM WPKSGQGLRE SSVMKTLLDE RRTSGTQPTT APVAAEEPRL ENVALENFVS 180
  181 IGWKLLDDSE LGWY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle