| Protein: | MET5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1442 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MET5.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [45..1442] | [58..1473] |
|
|
0.0 | [3..1439] | [21..1474] |
|
|
0.0 | [1..1442] | [1..1442] |
|
|
0.0 | [309..887] | [837..1453] |
|
|
0.0 | [833..1436] | [1..570] |
|
|
0.0 | [833..1436] | [3..572] |
|
|
0.0 | [833..1435] | [3..571] |
|
|
0.0 | [833..1435] | [1..569] |
|
Region A: Residues: [1-192] |
1 11 21 31 41 51
| | | | | |
1 MTASDLLTLP QLLAQYSSSA PQNKVFYTTS TKNSHSSFKG LESVATDATH LLNNQDPLNT 60
61 IKDQLSKDIL TTVFTDETTL VKSIHHLYSL PNKLPLVITV DLNLQDYSAI PALKDLSFPI 120
121 LISSDLQTAI SNADSSYKIA TSSLTPVFHF LNLEKIGTST AIEQDIDFPT LEIANEETKV 180
181 ALSEATDSLT NF
|
| Detection Method: |  |
| Confidence: | 13.18 |
| Match: | 1ik6A |
| Description: | E1-beta subunit of pyruvate dehydrogenase, Pyr module; E1-beta subunit of pyruvate dehydrogenase, C-domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [193-319] |
1 11 21 31 41 51
| | | | | |
1 ELVKGKESIT TVIVNLSPYD AEFSSVLPSN VGLIKIRVYR PWNFSKFLEI LPSSVTKIAV 60
61 LQGVSKKSQS NEFQPFLLDF FGNFNELVSR NIEQVVLTNI GNVNDYGNVI NTVISNINKK 120
121 EPDNNLF
|
| Detection Method: | |
| Confidence: | 13.18 |
| Match: | 1ik6A |
| Description: | E1-beta subunit of pyruvate dehydrogenase, Pyr module; E1-beta subunit of pyruvate dehydrogenase, C-domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [320-679] |
1 11 21 31 41 51
| | | | | |
1 LGESNEKAEE QAEVTQLISS VKKVVNLEDA YIKVLKQLFS SNLQILNQFS SETIEPSNPE 60
61 FGFGRFLKQE AQREELISLA KTSLDPSLYL SEDANKIVQL LSKWLSFNGR DLDEAQLQEA 120
121 NATGLEIFQL LQSNQDSSTV LKFLKIAPTS DSFIFKSSWL IGSDAWSYDL GHSGIQQVLS 180
181 SRKNINVLLI DSEPYDHRKQ NQDRKKDVGL YAMNYYSAYV ASVAVYASYT QLLTAIIEAS 240
241 KYNGPSIVLA YLPYNSENDT PLEVLKETKN AVESGYWPLY RFNPVYDDPS TDKEAFSLDS 300
301 SVIRKQLQDF LDRENKLTLL TRKDPSLSRN LKQSAGDALT RKQEKRSKAA FDQLLEGLSG 360
361
|
| Detection Method: | |
| Confidence: | 411.228787 |
| Match: | 1b0pA_ |
| Description: | Pyruvate-ferredoxin oxidoreductase, PFOR, domain I; Pyruvate-ferredoxin oxidoreductase, PFOR, domains VI; Pyruvate-ferredoxin oxidoreductase, PFOR, domain II; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; Pyruvate-ferredoxin oxidoreductase, PFOR, domain V |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetolactate synthase activity | 2.86666318994863 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 2.75586243560276 | bayes_pls_golite062009 |
| pyruvate dehydrogenase activity | 2.54367237239121 | bayes_pls_golite062009 |
| pyruvate dehydrogenase (acetyl-transferring) activity | 2.37626222601658 | bayes_pls_golite062009 |
| catalytic activity | 2.25537597692103 | bayes_pls_golite062009 |
| transferase activity, transferring aldehyde or ketonic groups | 2.18080419129242 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors | 1.3936144958597 | bayes_pls_golite062009 |
| oxidoreductase activity | 0.459800433209317 | bayes_pls_golite062009 |
| transferase activity | 0.413024577830522 | bayes_pls_golite062009 |
| binding | 0.39163264055064 | bayes_pls_golite062009 |
| protein binding | 0.149784186812647 | bayes_pls_golite062009 |
|
Region A: Residues: [680-857] |
1 11 21 31 41 51
| | | | | |
1 PPLHVYYASD GGNAANLAKR LAARASARGL KATVLSMDDI ILEELPGEEN VVFITSTAGQ 60
61 GEFPQDGKSF WEALKNDTDL DLASLNVAVF GLGDSEYWPR KEDKHYFNKP SQDLFKRLEL 120
121 LSAKALIPLG LGDDQDADGF QTAYSEWEPK LWEALGVSGA AVDDEPKPVT NEDIKRES
|
| Detection Method: | |
| Confidence: | 191.9691 |
| Match: | 1b1cA_ |
| Description: | NADPH-cytochrome p450 reductase, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 0.757525096811651 | bayes_pls_golite062009 |
| protein binding | 0.398609344827318 | bayes_pls_golite062009 |
| catalytic activity | 0.275631658558537 | bayes_pls_golite062009 |
|
Region A: Residues: [858-1117] |
1 11 21 31 41 51
| | | | | |
1 NFLRGTISEN LKDTSSGGVT HANEQLMKFH GIYTQDDRDI REIRKSQGLE PYYMFMARAR 60
61 LPGGKTTPQQ WLALDHLSDT SGNGTLKLTT RATFQIHGVL KKNLKHTLRG MNAVLMDTLA 120
121 AAGDVNRNVM VSALPTNAKV HQQIADMGKL ISDHFLPKTT AYHEVWLEGP EEQDDDPSWP 180
181 SIFENRKDGP RKKKTLVSGN ALVDIEPIYG PTYLPRKFKF NIAVPPYNDV DVLSIDVGLV 240
241 AIVNPETQIV EGYNVFVGGG
|
|
Region B: Residues: [1131-1202] |
1 11 21 31 41 51
| | | | | |
1 LGSCLGFVKT EDIIPPLEGI VIVQRDHGDR KDRKHARLKY TVDDMGVEGF KQKVEEYWGK 60
61 KFEPERPFEF KS
|
| Detection Method: | |
| Confidence: | 1386.0 |
| Match: | 1aop__ |
| Description: | Sulfite reductase, domains 1 and 3; Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1118-1130] |
1 11 21 31 41 51
| | | | | |
1 MGTTHNNKKT YPR
|
|
Region B: Residues: [1203-1442] |
1 11 21 31 41 51
| | | | | |
1 NIDYFGWIKD ETGLNHFTAF IENGRVEDTP DLPQKTGIRK VAEYMLKTNS GHFRLTGNQH 60
61 LVISNITDEH VAGIKSILKT YKLDNTDFSG LRLSSSSCVG LPTCGLAFAE SERFLPDIIT 120
121 QLEDCLEEYG LRHDSIIMRM TGCPNGCSRP WLGELALVGK APHTYNLMLG GGYLGQRLNK 180
181 LYKANVKDEE IVDYIKPLFK RYALEREEGE HFGDFCIRVG IIKPTTEGKY FHEDVSEDAY 240
241
|
| Detection Method: | |
| Confidence: | 1386.0 |
| Match: | 1aop__ |
| Description: | Sulfite reductase, domains 1 and 3; Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| sulfite reductase (NADPH) activity | 10.5477019483845 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on sulfur group of donors | 6.9484358652029 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor | 6.71341182064697 | bayes_pls_golite062009 |
| catalytic activity | 1.39967796334655 | bayes_pls_golite062009 |
| binding | 1.11461228884302 | bayes_pls_golite062009 |
| oxidoreductase activity | 1.08956206944325 | bayes_pls_golite062009 |
| protein binding | 0.618571973542447 | bayes_pls_golite062009 |
