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View Structure Prediction Details

Protein: HOC1
Organism: Saccharomyces cerevisiae
Length: 396 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HOC1.

Description E-value Query
Range
Subject
Range
HOC1_YEAST - Putative glycosyltransferase HOC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOC1 P...
gi|190409549 - gi|190409549|gb|EDV12814.1| mannosyltransferase [Saccharomyces cerevisiae RM11-1a]
HOC1 - Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit of a Golgi-localize...
0.0 [1..396] [1..396]
och1 - alpha-1,6-mannosyltransferase Och1
OCH1_SCHPO - Initiation-specific alpha-1,6-mannosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24...
0.0 [13..389] [3..395]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-95 [41..389] [1..365]
gi|17978673 - gi|17978673|gb|AAL49987.1| putative mannosyltransferase [Candida albicans]
6.0E-83 [75..389] [39..377]
gi|14161489 - gi|14161489|gb|AAK54761.1| putative mannosyltransferase [Paracoccidioides brasiliensis]
8.0E-51 [97..375] [63..336]
gi|18653302 - gi|18653302|gb|AAL77372.1|AF449195_7 putative glycosyl transferase [Vibrio cholerae]
8.0E-44 [88..322] [13..217]

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Predicted Domain #1
Region A:
Residues: [1-328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKTTKRASS FRRLMIFAII ALISLAFGVR YLFHNSNATD LQKILQNLPK EISQSINSAN  60
   61 NIQSSDSDLV QHFESLAQEI RHQQEVQAKQ FDKQRKILEK KIQDLKQTPP EATLRERIAM 120
  121 TFPYDSHVKF PAFIWQTWSN DEGPERVQDI KGMWESKNPG FAHEVLNHDV INALVHHYFY 180
  181 SIPEILETYE ALPSIILKID FFKYLILLVH GGVYADIDTF PVQPIPNWIP EELSPSDIGL 240
  241 IVGVEEDAQR ADWRTKYIRR LQFGTWIIQA KPGHPVLREI ISRIIETTLQ RKRDDQLNVN 300
  301 LRNDLNIMSW TGSGLWTDTI FTYFNDFM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
UDP-glycosyltransferase activity 6.01354989568484 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 5.98555597307566 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 5.66606808201136 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 5.62955108548526 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 5.60505224219681 bayes_pls_golite062009
mannosyltransferase activity 5.1732667004955 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 4.02812104984198 bayes_pls_golite062009
transferase activity 2.3313878748424 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.79751747857925 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
nucleotidyltransferase activity 1.47767908405723 bayes_pls_golite062009
N-acetyllactosamine synthase activity 0.925872529464618 bayes_pls_golite062009
lactose synthase activity 0.925872529464618 bayes_pls_golite062009
cytidylyltransferase activity 0.450701661234496 bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.386636074342689 bayes_pls_golite062009
binding 0.165472828059574 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [329-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSGVREKVTW KLFHNLNQPK LLSDVLVFPK FSFNCPNQID NDDPHKKFYF ITHLASQFWK  60
   61 NTPKVEQK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle