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View Structure Prediction Details

Protein: YJL216C
Organism: Saccharomyces cerevisiae
Length: 581 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJL216C.

Description E-value Query
Range		 Subject
Range
O16G_GEOTM - Oligo-1,6-glucosidase OS=Geobacillus thermoglucosidasius GN=malL PE=1 SV=1
 0.0 [9..581] [5..560]
IMA5_YEAST - Oligo-1,6-glucosidase IMA5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IMA5 PE=2 SV=...
YJL216C - Protein of unknown function, similar to alpha-D-glucosidases; transcriptionally activated by both Pd...
 0.0 [1..581] [1..581]
O16G_BACCE - Oligo-1,6-glucosidase OS=Bacillus cereus GN=malL PE=1 SV=1
 0.0 [7..581] [3..558]
gi|8096681 - gi|8096681|gb|AAF71997.1|AF216220_1 alpha-glucosidase [Bacillus sp. DG0303]
 0.0 [9..580] [5..559]
O16G_BACHD - Oligo-1,6-glucosidase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153...
O16G_BACHD - Oligo-1,6-glucosidase OS=Bacillus halodurans GN=malL PE=3 SV=1
 0.0 [8..579] [4..557]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [9..580] [21..583]
gi|580824 - gi|580824|emb|CAA54266.1| alpha-glucosidase [Bacillus sp.]
 0.0 [9..580] [21..583]
gi|221312940 - gi|221312940|ref|ZP_03594745.1| trehalose-6-phosphate hydrolase [Bacillus subtilis subsp. subtilis s...
TREC_BACSU - Trehalose-6-phosphate hydrolase OS=Bacillus subtilis (strain 168) GN=treA PE=1 SV=2
TREC_BACSU - Trehalose-6-phosphate hydrolase OS=Bacillus subtilis GN=treA PE=1 SV=2
gi|221322138 - gi|221322138|ref|ZP_03603432.1| trehalose-6-phosphate hydrolase [Bacillus subtilis subsp. subtilis s...
gi|221317865 - gi|221317865|ref|ZP_03599159.1| trehalose-6-phosphate hydrolase [Bacillus subtilis subsp. subtilis s...
 0.0 [1..580] [1..557]
O16G_BACCO - Oligo-1,6-glucosidase OS=Bacillus coagulans GN=malL PE=3 SV=1
 0.0 [8..581] [3..554]

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Predicted Domain #1
Region A:
Residues: [1-297] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIIHNPKWW KEATVYQIYP ASFKDSNNDG WGDLAGITSK LDYVKELGVD AIWVCPFYDS  60
   61 PQEDMGYDIA NYEKVWPRYG TNEDCFQMIE EAHKRGIKVI VDLVINHCSE EHEWFKESRS 120
  121 SKANPKRDWF FWRPPKGYDE KGNPIPPNNW RSFFGGSAWR YDEKTGEFFL HVFALGQPDF 180
  181 NWENEECRKA IYDSSVGYWL RHNVDGFRID VGSMYSKVEG LPDAPITDPT VPYQKGTEFF 240
  241 INGPRIHEYH KEMHNYMLSQ VPEGKEIMTV GEVGIGNEDD FRVYTSAKEG ELNMMFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1358.0
Match: 1uok__
Description: Oligo-1,6-glucosidase; Oligo-1,6, glucosidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 4.11319792356479 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.92012282533754 bayes_pls_golite062009
hydrolase activity 3.21770945631891 bayes_pls_golite062009
chitinase activity 2.45357334610104 bayes_pls_golite062009
structural molecule activity 2.28030619331997 bayes_pls_golite062009
trehalase activity 2.11042620996316 bayes_pls_golite062009
alpha-amylase activity 2.09193270404736 bayes_pls_golite062009
amylase activity 2.03484942782894 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
alpha-glucosidase activity 0.96543619590958 bayes_pls_golite062009
glucosidase activity 0.766503513427695 bayes_pls_golite062009
hexosaminidase activity 0.763360027922833 bayes_pls_golite062009
binding 0.63693798355947 bayes_pls_golite062009
carbohydrate binding 0.4998423581103 bayes_pls_golite062009
maltase activity 0.442635030512661 bayes_pls_golite062009
sugar binding 0.36459095255871 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 0.263065978664289 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [298-581] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKHTSVGENP KCKYELIPFT LKDFKLALAE SFLFIENTDC WSTIYLENHD QPRSVSRFGS  60
   61 DSPKWREISS KMLATLIISL TGTVFIYQGQ ELGMPNFKNR KIEQIKCVEG TGTYAAIKRD 120
  121 YGEDSEKMKK FFEALALISR DHGRTPFPWS ADEPSAGFSK DAKPWIDMNE SFRDGINAEA 180
  181 ELKDKNSVFF FWKKALQVRK EHKDILVYGH NFQFIDLDND KLFMFTKDTD NKKMFAVFNF 240
  241 SSDNTDFSVP DNEASYTMFF GNYANSNGDS RTLQPWEGRL YLLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1358.0
Match: 1uok__
Description: Oligo-1,6-glucosidase; Oligo-1,6, glucosidase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle