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View Structure Prediction Details

Protein: UTP18
Organism: Saccharomyces cerevisiae
Length: 594 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP18.

Description E-value Query
Range
Subject
Range
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [168..590] [847..1247]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [98..593] [1020..1483]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMATTAMNV SVPPPDEEEQ LLAKFVFGDT TDLQENLAKF NADFIFNEQE MDVEDQEDEG  60
   61 SESDNSEEDE AQNGELDHVN NDQLFFVDDG 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [91-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNEDSQDKNE DTMDVDDEDD SSSDDYSEDS EEAAWIDSDD EKIKVPILVT NKTKKLRTSY  60
   61 NESKINGVHY INRLRSQFEK IYPRPKWVDD ESDSELDDEE DDEEEGSNNV INGDINALTK 120
  121 ILSTTYNYKD TLSNSKLLPP K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [232-594]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLDIVRLKDA NASHPSHSAI QSLSFHPSKP LLLTGGYDKT LRIYHIDGKT NHLVTSLHLV  60
   61 GSPIQTCTFY TSLSNQNQQN IFTAGRRRYM HSWDLSLENL THSQTAKIEK FSRLYGHEST 120
  121 QRSFENFKVA HLQNSQTNSV HGIVLLQGNN GWINILHSTS GLWLMGCKIE GVITDFCIDY 180
  181 QPISRGKFRT ILIAVNAYGE VWEFDLNKNG HVIRRWKDQG GVGITKIQVG GGTTTTCPAL 240
  241 QISKIKQNRW LAVGSESGFV NLYDRNNAMT SSTPTPVAAL DQLTTTISNL QFSPDGQILC 300
  301 MASRAVKDAL RLVHLPSCSV FSNWPTSGTP LGKVTSVAFS PSGGLLAVGN EQGKVRLWKL 360
  361 NHY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.0
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
snoRNA binding 3.51833501249106 bayes_pls_golite062009
3.41022148055944 bayes_pls_golite062009
RNA binding 3.0829625416797 bayes_pls_golite062009
binding 2.22722319261713 bayes_pls_golite062009
transcription regulator activity 1.25687092973217 bayes_pls_golite062009
nucleic acid binding 1.20712373307552 bayes_pls_golite062009
structural molecule activity 1.20572493724069 bayes_pls_golite062009
protein binding 1.11897341394404 bayes_pls_golite062009
DNA binding 0.711274653406079 bayes_pls_golite062009
cytoskeletal protein binding 0.523052412917759 bayes_pls_golite062009
ligase activity 0.280267687917718 bayes_pls_golite062009
transcription factor activity 0.243992994917491 bayes_pls_golite062009
mRNA binding 0.0519838181830878 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle