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View Structure Prediction Details

Protein: YPS6
Organism: Saccharomyces cerevisiae
Length: 537 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPS6.

Description E-value Query
Range
Subject
Range
gi|28603728, gi|... - gi|6224889|gb|AAF05999.1|AF192333_1 pregnancy-associated glycoprotein-16 [Bos taurus], gi|28603728|r...
0.0 [1..428] [1..379]
gi|6180007 - gi|6180007|gb|AAF05750.1|AF191336_1 pregnancy-associated glycoprotein-11 [Capra hircus]
0.0 [1..428] [1..379]
PAG4_SHEEP - Pregnancy-associated glycoprotein 4 OS=Ovis aries PE=1 SV=2
0.0 [1..428] [1..379]
PEPA_CANLF - Pepsin A OS=Canis lupus familiaris GN=PGA PE=2 SV=1
0.0 [1..429] [1..386]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLISILSLL SSLMCSLTVL GSSASSYVKF PVQKLADIIN ICTQDVSTVF KRNEVLNTTV  60
   61 INGIGVYV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [245-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKIAYSLFLN GPDAHFGSIL FGAVDKSKYT GQLYTLP

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [411-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAYVVYDLEN YEISIAQASF NNQEEDIEVI SDTVPGATPA P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 553.38764
Match: 1ypsA_
Description: No description for 1ypsA_ was found.

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.68175187751599 bayes_pls_golite062009
aspartic-type peptidase activity 7.68175187751599 bayes_pls_golite062009
peptidase activity 3.09986068674657 bayes_pls_golite062009
endopeptidase activity 3.08503547117772 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.89367142096521 bayes_pls_golite062009
hydrolase activity 2.46470106080415 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 0.742107862879277 bayes_pls_golite062009
protein binding 0.401296299316154 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [69-244]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKMEIGTPPQ TLYLQLDTGS SDMIVNNADI AYCKSMSDGS DYASTDNYEL TATFNGLPST  60
   61 TISSEAYNTL CSYWGTFDAS NSSTFENNAT FFNNTYGDGT YYAGTYGTDV VSFENITLND 120
  121 FTFGVSNDTI GNPSGILGIS LPIAEFTDGI EYALALNRTP FIYDNFPMEL KNQGKI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [282-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQAFNTLGS NPGMIITAQS VAILDSESGN KTVSDIQFPV MLDSGTTFSY LPTEIAEAIG  60
   61 KSFDGEYSSD DQGYIFDCSK VNDTLLSVDF GGFNISANIS NFVTSAKDRC VLNVKQSEST 120
  121 YMLGDAFLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 553.38764
Match: 1ypsA_
Description: No description for 1ypsA_ was found.

Predicted Domain #3
Region A:
Residues: [452-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYFSTWVYKP GSPIGTGDFI NVSWTSYSEF SQYKSLLATA AQSDDASSFS SSGGSSESTT  60
   61 KKQNAGYKYR SSFSFSLLSF ISYFLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle