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View Structure Prediction Details

Protein: YPS6
Organism: Saccharomyces cerevisiae
Length: 537 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPS6.

Description E-value Query
Range
Subject
Range
gi|28603728, gi|... - gi|6224889|gb|AAF05999.1|AF192333_1 pregnancy-associated glycoprotein-16 [Bos taurus], gi|28603728|r...
0.0 [1..428] [1..379]
gi|6180007 - gi|6180007|gb|AAF05750.1|AF191336_1 pregnancy-associated glycoprotein-11 [Capra hircus]
0.0 [1..428] [1..379]
PAG4_SHEEP - Pregnancy-associated glycoprotein 4 OS=Ovis aries PE=1 SV=2
0.0 [1..428] [1..379]
PEPA_CANLF - Pepsin A OS=Canis lupus familiaris GN=PGA PE=2 SV=1
0.0 [1..429] [1..386]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLISILSLL SSLMCSLTVL GSSASSYVKF PVQKLADIIN ICTQDVSTVF KRNEVLNTTV  60
   61 INGIGVYV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [245-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKIAYSLFLN GPDAHFGSIL FGAVDKSKYT GQLYTLP

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [411-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAYVVYDLEN YEISIAQASF NNQEEDIEVI SDTVPGATPA P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 553.38764
Match: 1ypsA_
Description: No description for 1ypsA_ was found.

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.68175187751599 bayes_pls_golite062009
aspartic-type peptidase activity 7.68175187751599 bayes_pls_golite062009
peptidase activity 3.09986068674657 bayes_pls_golite062009
endopeptidase activity 3.08503547117772 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.89367142096521 bayes_pls_golite062009
hydrolase activity 2.46470106080415 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 0.742107862879277 bayes_pls_golite062009
protein binding 0.401296299316154 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [69-244]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKMEIGTPPQ TLYLQLDTGS SDMIVNNADI AYCKSMSDGS DYASTDNYEL TATFNGLPST  60
   61 TISSEAYNTL CSYWGTFDAS NSSTFENNAT FFNNTYGDGT YYAGTYGTDV VSFENITLND 120
  121 FTFGVSNDTI GNPSGILGIS LPIAEFTDGI EYALALNRTP FIYDNFPMEL KNQGKI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [282-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQAFNTLGS NPGMIITAQS VAILDSESGN KTVSDIQFPV MLDSGTTFSY LPTEIAEAIG  60
   61 KSFDGEYSSD DQGYIFDCSK VNDTLLSVDF GGFNISANIS NFVTSAKDRC VLNVKQSEST 120
  121 YMLGDAFLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 553.38764
Match: 1ypsA_
Description: No description for 1ypsA_ was found.

Predicted Domain #3
Region A:
Residues: [452-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYFSTWVYKP GSPIGTGDFI NVSWTSYSEF SQYKSLLATA AQSDDASSFS SSGGSSESTT  60
   61 KKQNAGYKYR SSFSFSLLSF ISYFLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.610 a.47.2 t-snare proteins
View Download 0.445 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.413 a.11.1 Acyl-CoA binding protein
View Download 0.620 a.46.1 Methionine synthase domain
View Download 0.542 a.68.1 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
View Download 0.407 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.384 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.380 f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.365 a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.360 a.59.1 PAH2 domain
View Download 0.343 a.2.7 tRNA-binding arm
View Download 0.333 d.58.13 Anticodon-binding domain of PheRS
View Download 0.326 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.316 a.39.1 EF-hand
View Download 0.313 a.112.1 Description not found.
View Download 0.312 a.4.5 "Winged helix" DNA-binding domain
View Download 0.306 d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.296 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.296 a.24.9 alpha-catenin/vinculin
View Download 0.291 d.15.1 Ubiquitin-like
View Download 0.284 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.273 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.272 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.272 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.262 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.251 a.101.1 Uteroglobin-like
View Download 0.249 a.85.1 Hemocyanin, N-terminal domain
View Download 0.246 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.241 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.237 a.64.2 Bacteriocin AS-48
View Download 0.235 a.65.1 Annexin
View Download 0.230 a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.229 d.58.9 RuBisCO, large subunit, small (N-terminal) domain
View Download 0.228 a.4.5 "Winged helix" DNA-binding domain
View Download 0.227 d.74.2 C-terminal domain of arginine repressor
View Download 0.221 a.7.7 BAG domain
View Download 0.220 a.7.1 Spectrin repeat
View Download 0.218 a.105.1 FIS-like
View Download 0.215 d.58.17 Metal-binding domain
View Download 0.211 a.11.2 Second domain of FERM
View Download 0.206 d.104.1 Class II aaRS and biotin synthetases
View Download 0.201 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.200 a.64.1 Saposin


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle