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View Structure Prediction Details

Protein: POR2
Organism: Saccharomyces cerevisiae
Length: 281 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POR2.

Description E-value Query
Range		 Subject
Range
VDAC2 - voltage-dependent anion channel 2
 0.0 [3..281] [30..311]
VDAC2_MOUSE - Voltage-dependent anion-selective channel protein 2 OS=Mus musculus GN=Vdac2 PE=1 SV=2
gi|53733651 - gb|AAH83965.1| Unknown (protein for MGC:98006) [Xenopus laevis]
 0.0 [3..279] [16..293]
VDAC2_RAT - Voltage-dependent anion-selective channel protein 2 OS=Rattus norvegicus GN=Vdac2 PE=1 SV=2
 0.0 [3..279] [16..293]
VDAC2_PIG - Voltage-dependent anion-selective channel protein 2 OS=Sus scrofa GN=VDAC2 PE=2 SV=1
 0.0 [3..279] [15..292]
gi|8574295 - gi|8574295|emb|CAB94711.2| voltage-dependent anion channel 2 [Bos taurus]
 0.0 [3..279] [15..292]
gi|149726367 - gi|149726367|ref|XP_001504459.1| PREDICTED: similar to voltage-dependent anion channel 1 [Equus caba...
VDAC1_RABIT - Voltage-dependent anion-selective channel protein 1 OS=Oryctolagus cuniculus GN=VDAC1 PE=2 SV=3
VDAC1_BOVIN - Voltage-dependent anion-selective channel protein 1 OS=Bos taurus GN=VDAC1 PE=1 SV=3
gi|57093539 - gi|57093539|ref|XP_531907.1| PREDICTED: similar to Voltage-dependent anion-selective channel protein...
 3.0E-98 [1..279] [1..281]

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Predicted Domain #1
Region A:
Residues: [1-281] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRFFNDIS RDVNGLFNRD FFHTNPLSLN ISTTTENGVN FTLKAKQGVT EGPIQTSVEG  60
   61 RFYDRKEGVS LSQSWSNQNR LNTRIEFSKI APGWKGDVNA FLTPQSIKNA KFNLSYAQKS 120
  121 FAARTSIDIL QPKDFVGSVT LGHRGFVGGT DIAYDTAAGL CARYAMSIGY LAREYSFILS 180
  181 TNNRQCATAS FFQNVNRYLQ VGTKATLQSK TSSNMNIEFV TRYVPDSISQ VKAKIADSGL 240
  241 TTLSYKRNLN KDISLGVGMS FNALQLTEPV HKFGWSLSFS P

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 149.0
Match: PF01459
Description: Eukaryotic porin

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.836 N/A N/A d.93.1 SH2 domain

Predicted Domain #2
Region A:
Residues: [143-281] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRGFVGGTDI AYDTAAGLCA RYAMSIGYLA REYSFILSTN NRQCATASFF QNVNRYLQVG  60
   61 TKATLQSKTS SNMNIEFVTR YVPDSISQVK AKIADSGLTT LSYKRNLNKD ISLGVGMSFN 120
  121 ALQLTEPVHK FGWSLSFSP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.09
Match: 1p4tA
Description: Outer membrane protein NspA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
channel activity 4.42063230929782 bayes_pls_golite062009
passive transmembrane transporter activity 4.42063230929782 bayes_pls_golite062009
wide pore channel activity 3.23380189399278 bayes_pls_golite062009
porin activity 3.07546403538822 bayes_pls_golite062009
transporter activity 2.79333283601576 bayes_pls_golite062009
transmembrane transporter activity 2.67610270255307 bayes_pls_golite062009
signal transducer activity 2.40233759168714 bayes_pls_golite062009
molecular transducer activity 2.40233759168714 bayes_pls_golite062009
receptor activity 2.38771290025999 bayes_pls_golite062009
binding 1.39766737580326 bayes_pls_golite062009
protein binding 0.709353859897791 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle