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View Structure Prediction Details

Protein: OYE2
Organism: Saccharomyces cerevisiae
Length: 400 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OYE2.

Description E-value Query
Range
Subject
Range
OYE3 - Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slig...
OYE3_YEAST - NADPH dehydrogenase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OYE3 PE=1 SV=2
0.0 [1..400] [1..400]
OYE1_SACPS - NADPH dehydrogenase 1 OS=Saccharomyces pastorianus GN=OYE1 PE=1 SV=3
gi|320802 - pir||A39495 NADPH2 dehydrogenase (EC 1.6.99.1) chain OYE1 - yeast (Saccharomyces cerevisiae) (strai...
0.0 [1..399] [1..399]
gi|5701740 - gi|5701740|dbj|BAA83083.1| LEDI-5a protein [Lithospermum erythrorhizon]
0.0 [13..392] [5..366]
KYE1_KLULA - Enoate reductase 1 OS=Kluyveromyces lactis GN=KYE1 PE=1 SV=2
KYE1_KLULA - Enoate reductase 1 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NR...
0.0 [1..399] [1..398]
OPR2_ARATH - 12-oxophytodienoate reductase 2 OS=Arabidopsis thaliana GN=OPR2 PE=1 SV=2
0.0 [4..390] [1..371]

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Predicted Domain #1
Region A:
Residues: [1-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFVKDFKPQ ALGDTNLFKP IKIGNNELLH RAVIPPLTRM RAQHPGNIPN RDWAVEYYAQ  60
   61 RAQRPGTLII TEGTFPSPQS GGYDNAPGIW SEEQIKEWTK IFKAIHENKS FAWVQLWVLG 120
  121 WAAFPDTLAR DGLRYDSASD NVYMNAEQEE KAKKANNPQH SITKDEIKQY VKEYVQAAKN 180
  181 SIAAGADGVE IHSANGYLLN QFLDPHSNNR TDEYGGSIEN RARFTLEVVD AVVDAIGPEK 240
  241 VGLRLSPYGV FNSMSGGAET GIVAQYAYVL GELERRAKAG KRLAFVHLVE PRVTNPFLTE 300
  301 GEGEYNGGSN KFAYSIWKGP IIRAGNFALH PEVVREEVKD PRTLIGYGRF FISNPDLVDR 360
  361 LEKGLPLNKY DRDTFYKMSA EGYIDYPTYE EALKLGWDKN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10123.0
Match: 1oya__
Description: Old yellow enzyme (OYE)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.50791144647902 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 2.11027907327307 bayes_pls_golite062009
catalytic activity 1.94749091175302 bayes_pls_golite062009
coenzyme binding 0.99234662301893 bayes_pls_golite062009
binding 0.724672865863266 bayes_pls_golite062009
nucleic acid binding 0.350068675013616 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.0276497014195508 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle