YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM13
Organism:	Saccharomyces cerevisiae
Length:	105 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM13.

Description	E-value	Query Range	Subject Range
gi\|190406804 - gi\|190406804\|gb\|EDV10071.1\| mitochondrial import inner membrane translocase subunit TIM13 [Saccharom... TIM13 - Mitochondrial intermembrane space protein, forms a complex with Tim8p that delivers a subset of hydr... TIM13_YEAST - Mitochondrial import inner membrane translocase subunit TIM13 OS=Saccharomyces cerevisiae (strain AT... gi\|151943459 - gi\|151943459\|gb\|EDN61770.1\| translocase of the inner membrane [Saccharomyces cerevisiae YJM789]	1.0E-31	[1..105]	[1..105]
tim13 - TIM22 inner membrane protein import complex subunit Tim13 TIM13_SCHPO - Mitochondrial import inner membrane translocase subunit tim13 OS=Schizosaccharomyces pombe (strain 9...	7.0E-22	[1..102]	[1..93]
TIM9_MESCR - Mitochondrial import inner membrane translocase subunit Tim9 OS=Mesembryanthemum crystallinum GN=TIM...	4.0E-19	[17..99]	[2..89]
TIM9_ORYSA, IM09... - (Q9XGX7) Mitochondrial import inner membrane translocase subunit Tim9, (Q9XGX7) Mitochondrial import...	2.0E-18	[17..98]	[2..88]
TIM8B_MOUSE - Mitochondrial import inner membrane translocase subunit Tim8 B OS=Mus musculus GN=Timm8b PE=1 SV=1 TIM8B_RAT - Mitochondrial import inner membrane translocase subunit Tim8 B OS=Rattus norvegicus GN=Timm8b PE=3 S...	7.0E-18	[22..99]	[1..81]
gi\|5107178, gi\|7... - gi\|74096149\|ref\|NP_001027735.1\| small zinc finger-like protein [Ciona intestinalis], gi\|5107178\|gb\|A...	1.0E-17	[29..105]	[1..83]
gi\|114640332 - gi\|114640332\|ref\|XP_001146364.1\| PREDICTED: translocase of inner mitochondrial membrane 8 homolog B ... TIMM8B - translocase of inner mitochondrial membrane 8 homolog B (yeast) ENSCJAT00000021390 - null	2.0E-17	[22..99]	[1..81]
TIM9_ARATH - Mitochondrial import inner membrane translocase subunit TIM9 OS=Arabidopsis thaliana GN=TIM9 PE=1 SV...	1.0E-16	[17..99]	[2..89]
TIM8_NEUCR - Mitochondrial import inner membrane translocase subunit tim8 OS=Neurospora crassa (strain ATCC 24698... TIM8_NEUCR, IM08... - Mitochondrial import inner membrane translocase subunit tim-8 OS=Neurospora crassa GN=tim-8 PE=1 SV=...	4.0E-16	[23..101]	[9..92]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLSSIFGGG APSQQKEAAT TAKTTPNPIA KELKNQIAQE LAVANATELV NKISENCFEK  60
   61 CLTSPYATRN DACIDQCLAK YMRSWNVISK AYISRIQNAS ASGEI

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	25.387216
Match:	PF02953
Description:	Tim10/DDP family zinc finger

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
protein transporter activity	3.96569591038426	bayes_pls_golite062009
transporter activity	3.42555440535265	bayes_pls_golite062009
protein transmembrane transporter activity	3.05578860381335	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	2.52072322460318	bayes_pls_golite062009
macromolecule transmembrane transporter activity	2.52072322460318	bayes_pls_golite062009
substrate-specific transporter activity	2.26454691978513	bayes_pls_golite062009
transmembrane transporter activity	2.01475009173074	bayes_pls_golite062009
binding	1.95236231715199	bayes_pls_golite062009
protein binding	1.54231655177329	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.5410808613005	bayes_pls_golite062009
unfolded protein binding	0.0997632819038001	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: