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View Structure Prediction Details

Protein: YGR071C
Organism: Saccharomyces cerevisiae
Length: 860 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGR071C.

Description E-value Query
Range
Subject
Range
YGR071C - Putative protein of unknown function; deletion mutant has increased glycogen accumulation and displa...
gi|190406908 - gi|190406908|gb|EDV10175.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|151943349 - gi|151943349|gb|EDN61662.1| conserved protein [Saccharomyces cerevisiae YJM789]
ENV11_YEAST - Late endosome and vacuole interface protein 11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
0.0 [1..860] [1..860]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTALDDLHG DLVTLEDNEI INNSDHSSSH STSHEEEDEE EDDTEDIELI EKDGNKILSS  60
   61 RIHPEDEIIN DG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNIWIPVQML KKNIAKFWSH FLAIEKKLTK VKCKHCGEIL TRSDASLTKT FRSHLKTKHN  60
   61 ISANKNFYSM NFTVGDSNLK 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.508638
Match: PF02892
Description: BED zinc finger

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
nuclease activity 0.684822695593649 bayes_pls_golite062009
catalytic activity 0.402379787166751 bayes_pls_golite062009
hydrolase activity 0.253454833507999 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.223965050767284 bayes_pls_golite062009
binding 0.0417104526044634 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [153-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNTSSTEITR RHGYDSLTFN SDQSFKCFDI GKLQSSNYLS ISQLVAIVIA SENLPLNFFE  60
   61 NVSFKSLLSK FHRIPPLTTN IIEESIIGLS KSIDELIRRS ISRNDTQLPF TIHLSDSKES 120
  121 NQPLYLKYSR EIRAQLSNLD LSHLISVNFT ELAGKRSLFS LQLFDNTNKV SKGLPLSIFV 180
  181 RKTTDIDISV WQEQLNNLYS KYPGLQKSVI SITLPQSHYT MVLENRNSHN FTFHSGSVRE 240
  241 IKYHTCIVSE LLHCFLQPLF NVPTESMLSS FSVAKENHSG GSLLDSLIDF SHIDLSSTIL 300
  301 GKI

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.13
Match: 1h6kA
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [456-656]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CCLIEEVNLN DSLKSDFLLY CQNYTQPNCN ELTSILSCNC DRFSALKSIL EKFANLVPFF  60
   61 KSINSHLENE SLSESDFRLI NTVEETLRTF EQSIEYFASS APLKFTHTLV FIIKFELYLT 120
  121 EIIRSFKFTK SKKPFEKILA RLLKVKDLYL LDDVNLIGAF LYPSIFQSKS LLNEIFGTTS 180
  181 VNKIVHNMTK IVLRYLKNFI N

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.13
Match: 1h6kA
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [657-736]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITNFRSSNSG GESGRNSGNN LLSDYEAIFM KESRDVELLC NTKLTAPLTE DSLLVQIIRD  60
   61 DLLRYVNRIA HELPNAYHDY 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.28
Match: 1e8yA
Description: Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [737-860]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNDNDISFDG SHFTKHELSE ENDSNSGEWC LNPMEETFDI HIPISDSIWN NYISSKNKIE  60
   61 VIDILLQLLS VNSTSSIRSE LSSLTANQDF STKLSEETIK IKLLNSQFNL EKINFHSGSI 120
  121 FDAC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle