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View Structure Prediction Details

Protein: BST1
Organism: Saccharomyces cerevisiae
Length: 1029 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BST1.

Description E-value Query
Range
Subject
Range
BST1_SCHPO - GPI inositol-deacylase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=bst1 PE=3 SV=1
SPAC824.02 - GPI inositol deacylase
0.0 [15..1024] [47..1108]
BST1_YEAST - GPI inositol-deacylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BST1 PE=1 SV=1
BST1 - GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents product...
0.0 [1..1029] [1..1029]
gi|15229470 - gi|15229470|ref|NP_189368.1| unknown protein [Arabidopsis thaliana]
0.0 [59..425] [16..422]
gi|18447638 - gi|18447638|gb|AAL68379.1| SD04405p [Drosophila melanogaster]
0.0 [52..392] [2..348]
CE06462 - Yeast hyptothetical protein YFC5 like status:Partially_confirmed UniProt:Q22561 protein_id:CAA98541....
3.0E-80 [36..369] [5..318]

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Predicted Domain #1
Region A:
Residues: [1-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIRRLVSVI TRPIINKVNS SGQYSRVLAT REDQDKASPK YMNNDKIAKK PYTYRLFSIL  60
   61 GILSICSLLL ISLLKPFNGA DAPQCESIYM FPSYARIDGF DERYTPLAHK YHLYLYREQS 120
  121 VDREPLNGDE LQLDGIPVLF IPGNAGSFRQ CRSIASACSN IYFDSNTRAT LRNENVRNLD 180
  181 FFTADFNEDF TAFHGETMLD QAEYLNDAIK YILSLYERTP DYPHPKPQSV IIVGHSMGGI 240
  241 VSRVMLTLKN HVPGSISTIL TLSSPHAASP VTFDGDILKL YKNTNEYWRK QLSQNDSFFS 300
  301 KNISLVSITG GILDTTLPAD YASVEDLVSL ENGFTSFTTT IPDVWTPIDH LAIVWCKQLR 360
  361 EVLARLLLES IDASKPEKVK PLNQRLQIAR KLLLSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [397-1029]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEDYSWMNSK LNYPQENLQE FSDNFFSDYA TLEMNDVLDF EMFNLEKWHN NYTKINIPSN  60
   61 ISSTEHLHFT LLTSLDMPMI YFCTESRVNL SCITAVDSIL TVPRSSKDTQ FAADSSFGEA 120
  121 KNPFKAVSVG KNILQKYDYL MISKPTYGEF SEQEGMEDNQ GFLLALLRNV SNVQIVNTTP 180
  181 SQILLFGEQL HLDGKDIEQV ISFSNLWDSL LSYKLETKIE ASNEGIASEE TLFQPFIRQW 240
  241 VYEPFESKWH LNIINKSLDI NMHNVAPFIP LNESEPRSLQ LSFFIPPGMS LEAKMTINWS 300
  301 LTLKMLFIRY RLALASFPVA FIALVLSYQF YWYNKTSEFP SFDSTLGYIL RKHGILMFFT 360
  361 LFLASPVVNN KLVQRILYLL DPVGLNYPFL LSERNMHANF YYLGIRDWFM STIGILFGVM 420
  421 TVGLLALVSK IFGSLEILVI FLQRKLSKKN TEDKEAFDTI EHKAYGKGRL MASVLLLLLV 480
  481 FFHIPYQMAF VISLVIQIAT CIRVALLKLS NNEQKLNLLN YNMTLLLLLL FVSAINIPII 540
  541 IVFLHNVAIK WETSFRSHHN ILAVAPIIFL VGNNSIFKMP NSVPLDTWDG KVTIILFVYL 600
  601 TVFSFIYGIR NLYWIHHLVN IICAWLLFFE TIH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
hydrolase activity 2.62575321936198 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.54257949495452 bayes_pls_golite062009
catalytic activity 1.2983708611085 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.05574518895749 bayes_pls_golite062009
phospholipase activity 0.798264075802939 bayes_pls_golite062009
peptidase activity 0.76591567453342 bayes_pls_golite062009
binding 0.453877824078419 bayes_pls_golite062009
lipase activity 0.450520363288288 bayes_pls_golite062009
pyrophosphatase activity 0.0108860947932076 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.00279712309330893 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [400-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSWMNSKLNY PQENLQEFSD NFFSDYATLE MNDVLDFEMF NLEKWHNNYT KINIPSNISS  60
   61 TEHLHFTLLT SLDMPMIYFC TESRVNLSCI TAVDSILTVP RSSKDTQFA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [509-671]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADSSFGEAKN PFKAVSVGKN ILQKYDYLMI SKPTYGEFSE QEGMEDNQGF LLALLRNVSN  60
   61 VQIVNTTPSQ ILLFGEQLHL DGKDIEQVIS FSNLWDSLLS YKLETKIEAS NEGIASEETL 120
  121 FQPFIRQWVY EPFESKWHLN IINKSLDINM HNVAPFIPLN ESE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [672-777]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRSLQLSFFI PPGMSLEAKM TINWSLTLKM LFIRYRLALA SFPVAFIALV LSYQFYWYNK  60
   61 TSEFPSFDST LGYILRKHGI LMFFTLFLAS PVVNNKLVQR ILYLLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [778-1029]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVGLNYPFLL SERNMHANFY YLGIRDWFMS TIGILFGVMT VGLLALVSKI FGSLEILVIF  60
   61 LQRKLSKKNT EDKEAFDTIE HKAYGKGRLM ASVLLLLLVF FHIPYQMAFV ISLVIQIATC 120
  121 IRVALLKLSN NEQKLNLLNY NMTLLLLLLF VSAINIPIII VFLHNVAIKW ETSFRSHHNI 180
  181 LAVAPIIFLV GNNSIFKMPN SVPLDTWDGK VTIILFVYLT VFSFIYGIRN LYWIHHLVNI 240
  241 ICAWLLFFET IH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle