| Protein: | RPH1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 796 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPH1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [335..796] | [20..585] |
|
|
0.0 | [340..796] | [11..567] |
|
Region A: Residues: [1-59] |
1 11 21 31 41 51
| | | | | |
1 MTKLIAPSEI VGGVPVFKPT YEQFEDFYAY CKAINKYGMK SGVVKVIPPK EWKDKLDLP
|
| Detection Method: |  |
| Confidence: | 24.920819 |
| Match: | PF02375 |
| Description: | jmjN domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [60-198] |
1 11 21 31 41 51
| | | | | |
1 YSAETLQKIK IKSPIQQHIS GNKGLFMVQN VEKNKTYNII QWKDLSKDYV PPEDPKARRN 60
61 SRKGSVSKST KLKLKNFESS FNIDDFEQFR TEYTIDLSDF QNTERLKFLE EYYWKTLNFT 120
121 TPMYGADTPG SIFPEGLNV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [199-378] |
1 11 21 31 41 51
| | | | | |
1 WNVAKLPNIL DHMETKVPGV NDSYLYAGLW KASFSWHLED QDLYSINYIH FGAPKQWYSI 60
61 PQEDRFKFYK FMQEQFPEEA KNCPEFLRHK MFLASPKLLQ ENGIRCNEIV HHEGEFMITY 120
121 PYGYHAGFNY GYNLAESVNF ALEEWLPIGK KAGKCHCISD SVEIDVKKLA KSWRDNNKES 180
181
|
| Detection Method: | |
| Confidence: | 57.05061 |
| Match: | PF02373 |
| Description: | JmjC domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [379-431] |
1 11 21 31 41 51
| | | | | |
1 KGTPPLNQLP NPAMPLLHRP TLKEMESSSL RSTSPDVGHF SNFKSKSSGV SSP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.482 | 0.969 | specific transcriptional repressor activity | a.4.1 | Homeodomain-like |
| Term | Confidence | Notes |
| transcription regulator activity | 4.70988788192472 | bayes_pls_golite062009 |
| nucleic acid binding | 4.58713908116892 | bayes_pls_golite062009 |
| DNA binding | 4.56219307357342 | bayes_pls_golite062009 |
| transcription factor activity | 3.50954949535763 | bayes_pls_golite062009 |
| transcription repressor activity | 3.27542149084008 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.22082323675675 | bayes_pls_golite062009 |
| binding | 3.10743787485868 | bayes_pls_golite062009 |
| transcription activator activity | 2.19952417915035 | bayes_pls_golite062009 |
| chromatin binding | 2.18464662431232 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.63161912031789 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.42975942698743 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.42446448463712 | bayes_pls_golite062009 |
| transcription factor binding | 1.39608963544799 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.34049786451995 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.1674904189309 | bayes_pls_golite062009 |
| protein binding | 1.00484935878505 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.77874411480713 | bayes_pls_golite062009 |
| histone binding | 0.687710658383448 | bayes_pls_golite062009 |
| catalytic activity | 0.245893663605433 | bayes_pls_golite062009 |
|
Region A: Residues: [432-587] |
1 11 21 31 41 51
| | | | | |
1 LLSRMKDYSN IVEPTLEDPT LKLKRISSFQ EQPLNKLLKR ETSQTAMLTD HEDNIVAMSL 60
61 TSMANSAASS PRLPLSRLNS SNELSNAQPL LDMTNNTLAF PRPNGPSGLN PLLYISNKNI 120
121 SGISHSAPHS PVNPNISLIK RVKSPNIVTL NISRES
|
| Detection Method: | |
| Confidence: | 55.927757 |
| Match: | 1ubdC_ |
| Description: | Ying-yang 1 (yy1, zinc finger domain) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [588-676] |
1 11 21 31 41 51
| | | | | |
1 SRSPIALNYE ARQQHSQQHS FSTPSTVSNL STSVLGPLSD TNDIKTPHPE RPNHKTANRI 60
61 LKKESPVETS KSNLILSKVA STRQEDSFT
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [677-796] |
1 11 21 31 41 51
| | | | | |
1 SRNDDLDKEQ GSSPLNSKFA PEEIVLSGKN KIYICKECQR KFSSGHHLTR HKKSVHSGEK 60
61 PHSCPKCGKR FKRRDHVLQH LNKKIPCISN ETTVDAPIMN PTVQPQDGKA AINQQSTPLN 120
121
|
| Detection Method: | |
| Confidence: | 94.9897 |
| Match: | 1meyG_ |
| Description: | Designed zinc finger protein |
Matching Structure (courtesy of the PDB): |
|
