| Protein: | MET6 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 767 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MET6.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [2..767] | [1..763] |
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0.0 | [2..767] | [1..763] |
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0.0 | [2..767] | [1..763] |
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0.0 | [1..767] | [1..767] |
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0.0 | [2..767] | [1..763] |
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0.0 | [2..767] | [21..782] |
|
Region A: Residues: [1-104] |
1 11 21 31 41 51
| | | | | |
1 MVQSAVLGFP RIGPNRELKK ATEGYWNGKI TVDELFKVGK DLRTQNWKLQ KEAGVDIIPS 60
61 NDFSFYDQVL DLSLLFNVIP DRYTKYDLSP IDTLFAMGRG LQRK
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity | 6.40786073037099 | bayes_pls_golite062009 |
| 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity | 6.40786073037099 | bayes_pls_golite062009 |
| uroporphyrinogen decarboxylase activity | 3.13638443707338 | bayes_pls_golite062009 |
| S-methyltransferase activity | 3.0142199413027 | bayes_pls_golite062009 |
| catalytic activity | 2.37862248560593 | bayes_pls_golite062009 |
| binding | 1.590130518929 | bayes_pls_golite062009 |
| carbon-carbon lyase activity | 1.54242506764415 | bayes_pls_golite062009 |
| carboxy-lyase activity | 1.52150758949987 | bayes_pls_golite062009 |
| lyase activity | 0.825209465219608 | bayes_pls_golite062009 |
| protein binding | 0.21865699924356 | bayes_pls_golite062009 |
|
Region A: Residues: [105-401] |
1 11 21 31 41 51
| | | | | |
1 ATETEKAVDV TALEMVKWFD SNYHYVRPTF SKTTQFKLNG QKPVDEFLEA KELGIHTRPV 60
61 LLGPVSYLFL GKADKDSLDL EPLSLLEQLL PLYTEILSKL ASAGATEVQI DEPVLVLDLP 120
121 ANAQAAIKKA YTYFGEQSNL PKITLATYFG TVVPNLDAIK GLPVAALHVD FVRAPEQFDE 180
181 VVAAIGNKQT LSVGIVDGRN IWKNDFKKSS AIVNKAIEKL GADRVVVATS SSLLHTPVDL 240
241 NNETKLDAEI KGFFSFATQK LDEVVVITKN VSGQDVAAAL EANAKSVESR GKSKFIH
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [402-440] |
1 11 21 31 41 51
| | | | | |
1 DAAVKARVAS IDEKMSTRAA PFEQRLPEQQ KVFNLPLFP
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Region B: Residues: [674-767] |
1 11 21 31 41 51
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1 VSIEFSKKDD ANYIAEFKNY PNHIGLGLFD IHSPRIPSKD EFIAKISTIL KSYPAEKFWV 60
61 NPDCGLKTRG WEETRLSLTH MVEAAKYFRE QYKN
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| Detection Method: | |
| Confidence: | 11.96 |
| Match: | 1j93A |
| Description: | Uroporphyrinogen decarboxylase, UROD |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [441-673] |
1 11 21 31 41 51
| | | | | |
1 TTTIGSFPQT KDIRINRNKF NKGTISAEEY EKFINSEIEK VIRFQEEIGL DVLVHGEPER 60
61 NDMVQYFGEQ INGYAFTVNG WVQSYGSRYV RPPIIVGDLS RPKAMSVKES VYAQSITSKP 120
121 VKGMLTGPIT CLRWSFPRDD VDQKTQAMQL ALALRDEVND LEAAGIKVIQ VDEPALREGL 180
181 PLREGTERSA YYTWAAEAFR VATSGVANKT QIHSHFCYSD LDPNHIKALD ADV
|
| Detection Method: | |
| Confidence: | 11.96 |
| Match: | 1j93A |
| Description: | Uroporphyrinogen decarboxylase, UROD |
| Matching Structure (courtesy of the PDB): |
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