| Protein: | ISC1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 477 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISC1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..477] | [1..477] |
|
|
5.0E-73 | [108..463] | [1..347] |
|
|
7.0E-56 | [39..369] | [9..307] |
|
|
4.0E-55 | [39..369] | [9..307] |
|
|
5.0E-55 | [39..369] | [9..307] |
|
|
8.0E-49 | [20..344] | [277..592] |
|
|
8.0E-49 | [38..358] | [5..289] |
|
|
3.0E-48 | [24..344] | [21..333] |
|
Region A: Residues: [1-346] |
1 11 21 31 41 51
| | | | | |
1 MYNRKDRDVH ERKEDGQSEF EALNGTNAIM SDNSKAYSIK FLTFNTWGLK YVSKHRKERL 60
61 RAIADKLAGH SMLTPISDEL LPNGGDSNEN EDYDVIALQE IWCVEDWKYL ASACASKYPY 120
121 QRLFHSGILT GPGLAILSKV PIESTFLYRF PINGRPSAVF RGDWYVGKSI AITVLNTGTR 180
181 PIAIMNSHMH APYAKQGDAA YLCHRSCQAW DFSRLIKLYR QAGYAVIVVG DLNSRPGSLP 240
241 HKFLTQEAGL VDSWEQLHGK QDLAVIARLS PLQQLLKGCT TCDSLLNTWR AQRQPDEACR 300
301 LDYALIDPDF LQTVDAGVRF TERIPHLDCS VSDHFAYSCT LNIVPQ
|
| Detection Method: |  |
| Confidence: | 41.39794 |
| Match: | 1hd7A_ |
| Description: | DNA repair endonuclease Hap1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| inositol or phosphatidylinositol phosphatase activity | 3.64123197004285 | bayes_pls_golite062009 |
| phosphatidylinositol bisphosphate phosphatase activity | 3.0061663893933 | bayes_pls_golite062009 |
| phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | 2.90758198006555 | bayes_pls_golite062009 |
| phosphoinositide 5-phosphatase activity | 2.90758198006555 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.26056838384313 | bayes_pls_golite062009 |
| hydrolase activity | 2.21673584332033 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.87742719915012 | bayes_pls_golite062009 |
| catalytic activity | 1.76511376991978 | bayes_pls_golite062009 |
| inositol-polyphosphate 5-phosphatase activity | 1.69034937361985 | bayes_pls_golite062009 |
| inositol trisphosphate phosphatase activity | 1.67310905470506 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 1.24865228320008 | bayes_pls_golite062009 |
| nuclease activity | 1.10772848766193 | bayes_pls_golite062009 |
| binding | 0.762705099992601 | bayes_pls_golite062009 |
| lipid phosphatase activity | 0.494223168454777 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 0.469778612465362 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.466524009072462 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.414974033231176 | bayes_pls_golite062009 |
| exonuclease activity | 0.408287239827419 | bayes_pls_golite062009 |
| protein binding | 0.224287899263963 | bayes_pls_golite062009 |
| phosphatase activity | 0.00559251346312178 | bayes_pls_golite062009 |
| nucleic acid binding | 0.0053559034506292 | bayes_pls_golite062009 |
|
Region A: Residues: [347-477] |
1 11 21 31 41 51
| | | | | |
1 GTESRPSTSV KRAKTHDREL ILQRYSNYET MIECIHTYLK TAQRQKFFRG LHFWASILLL 60
61 IASLVVTTFT ANKAGWSSIF WVLFAIAVSI SGTIDGAISF LFGRSEIRAL IEVEQEVLDA 120
121 EHHLQTFLSE K
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
