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View Structure Prediction Details

Protein: SPS2
Organism: Saccharomyces cerevisiae
Length: 502 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPS2.

Description E-value Query
Range
Subject
Range
SPS2 - Protein expressed during sporulation, redundant with Sps22p for organization of the beta-glucan laye...
SPS2_YEAST - Sporulation-specific protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPS2 PE=1...
4.0E-83 [1..502] [1..502]
gi|12054727 - gi|12054727|emb|CAC20606.1| internalin B [Listeria ivanovii]
4.0E-53 [49..437] [7..390]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-48 [5..374] [56..410]
gi|224502275 - gi|224502275|ref|ZP_03670582.1| internalin A [Listeria monocytogenes FSL R2-561]
INLA_LISMO - Internalin-A OS=Listeria monocytogenes GN=inlA PE=1 SV=3
INLA_LISMO - Internalin-A OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=inlA PE=1 SV=1
5.0E-48 [5..374] [56..410]
gi|149674, gi|22... - gi|22347564|gb|AAM95927.1| internalin A precursor [Listeria monocytogenes], gi|149674|gb|AAA25289.1|...
8.0E-47 [6..374] [1..354]
gi|25497672 - pir||C97303 hypothetical protein CAC3280 [imported] - Clostridium acetobutylicum
gi|15026357, gi|... - gi|15896525|ref|NP_349874.1| ChW repeat-containing protein [Clostridium acetobutylicum ATCC 824], gi...
2.0E-44 [13..391] [472..840]

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Predicted Domain #1
Region A:
Residues: [1-62]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIWKTQTFF TSISVIQIVN KETKVSTKKE KDSMLNQLNT ILRFLFLFLQ LIKSSAAVEP  60
   61 NG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
receptor activity 1.64987101746707 bayes_pls_golite062009
transmembrane receptor activity 1.34503183418293 bayes_pls_golite062009
binding 1.08525898490902 bayes_pls_golite062009
protein binding 0.669091045213589 bayes_pls_golite062009
signal transducer activity 0.499118819144462 bayes_pls_golite062009
molecular transducer activity 0.499118819144462 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [63-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPNILDHNIM LVNTNATIPK KEQTDFEVIS PTKQTQVDED CKKGLYHIEN AGNLIELQAK  60
   61 CWKVVGNIEI SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.154902
Match: 1h6uA_
Description: Internalin H
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [135-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYSGSLIDLG LIREIEGDLI IKNNKHIFRI QGYNLESLGK LELDSLTSFV SLDFPALKEV  60
   61 ETVDWRVLPI LSSVVINGNI KKIKNIIISD TALTSIDYFN NVKKVDIFNI NNNRFLENLF 120
  121 ASLESVTKQL TVHSNAKELE LDLSNLHTVE NMTIKDVSEI KLAKLSSVNS SLEFIENQFS 180
  181 SLELPLLAKV QGTLGLIDNK NLKKLNFSNA TDIQGGLMIA NNTELAKIDF FPKLRQIGGA 240
  241 IYFEGSFDKI DLPELKLVKG SAYIKSSSEE LNCEEFTSPK AGRSIIRGGK IECTSGMKSK 300
  301 MLNVDEEGNV LGKQET

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.0
Match: 1jl5A_
Description: Leucine rich effector protein YopM
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [451-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNDNGKKEKG KNGAKSQGSS KKMENSAPKN IFIDAFKMSV YAVFTVLFSI IF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle