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View Structure Prediction Details

Protein: SPS2
Organism: Saccharomyces cerevisiae
Length: 502 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPS2.

Description E-value Query
Range
Subject
Range
SPS2 - Protein expressed during sporulation, redundant with Sps22p for organization of the beta-glucan laye...
SPS2_YEAST - Sporulation-specific protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPS2 PE=1...
4.0E-83 [1..502] [1..502]
gi|12054727 - gi|12054727|emb|CAC20606.1| internalin B [Listeria ivanovii]
4.0E-53 [49..437] [7..390]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-48 [5..374] [56..410]
gi|224502275 - gi|224502275|ref|ZP_03670582.1| internalin A [Listeria monocytogenes FSL R2-561]
INLA_LISMO - Internalin-A OS=Listeria monocytogenes GN=inlA PE=1 SV=3
INLA_LISMO - Internalin-A OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=inlA PE=1 SV=1
5.0E-48 [5..374] [56..410]
gi|149674, gi|22... - gi|22347564|gb|AAM95927.1| internalin A precursor [Listeria monocytogenes], gi|149674|gb|AAA25289.1|...
8.0E-47 [6..374] [1..354]
gi|25497672 - pir||C97303 hypothetical protein CAC3280 [imported] - Clostridium acetobutylicum
gi|15026357, gi|... - gi|15896525|ref|NP_349874.1| ChW repeat-containing protein [Clostridium acetobutylicum ATCC 824], gi...
2.0E-44 [13..391] [472..840]

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Predicted Domain #1
Region A:
Residues: [1-62]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIWKTQTFF TSISVIQIVN KETKVSTKKE KDSMLNQLNT ILRFLFLFLQ LIKSSAAVEP  60
   61 NG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.597 a.65.1 Annexin
View Download 0.702 a.16.1 S15/NS1 RNA-binding domain
View Download 0.644 a.2.7 tRNA-binding arm
View Download 0.566 a.30.1 ROP protein
View Download 0.674 a.16.1 S15/NS1 RNA-binding domain
View Download 0.499 a.30.1 ROP protein
View Download 0.486 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.484 a.16.1 S15/NS1 RNA-binding domain
View Download 0.481 a.17.1 p8-MTCP1
View Download 0.479 f.15.1 Small-conductance potassium channel
View Download 0.469 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.465 f.13.1 Family A G protein-coupled receptor-like
View Download 0.458 f.13.1 Family A G protein-coupled receptor-like
View Download 0.455 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.451 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.448 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.448 a.17.1 p8-MTCP1
View Download 0.444 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.433 a.17.1 p8-MTCP1
View Download 0.429 f.13.1 Family A G protein-coupled receptor-like
View Download 0.429 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.425 f.13.1 Family A G protein-coupled receptor-like
View Download 0.423 f.13.1 Family A G protein-coupled receptor-like
View Download 0.410 a.16.1 S15/NS1 RNA-binding domain
View Download 0.404 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.399 f.13.1 Family A G protein-coupled receptor-like
View Download 0.398 a.30.1 ROP protein
View Download 0.396 a.17.1 p8-MTCP1
View Download 0.394 a.4.5 "Winged helix" DNA-binding domain
View Download 0.389 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.386 a.17.1 p8-MTCP1
View Download 0.380 a.16.1 S15/NS1 RNA-binding domain
View Download 0.380 a.2.7 tRNA-binding arm
View Download 0.379 a.2.3 Chaperone J-domain
View Download 0.372 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.370 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.367 f.13.1 Family A G protein-coupled receptor-like
View Download 0.366 a.30.1 ROP protein
View Download 0.362 f.13.1 Family A G protein-coupled receptor-like
View Download 0.361 a.2.7 tRNA-binding arm
View Download 0.361 f.13.1 Family A G protein-coupled receptor-like
View Download 0.356 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.351 f.13.1 Family A G protein-coupled receptor-like
View Download 0.349 f.13.1 Family A G protein-coupled receptor-like
View Download 0.348 f.13.1 Family A G protein-coupled receptor-like
View Download 0.345 a.16.1 S15/NS1 RNA-binding domain
View Download 0.337 a.30.1 ROP protein
View Download 0.333 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.332 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.332 a.17.1 p8-MTCP1
View Download 0.331 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.329 a.16.1 S15/NS1 RNA-binding domain
View Download 0.323 a.2.7 tRNA-binding arm
View Download 0.321 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.319 a.16.1 S15/NS1 RNA-binding domain
View Download 0.317 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.315 a.4.5 "Winged helix" DNA-binding domain
View Download 0.314 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.313 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.311 i.1.1 Ribosome and ribosomal fragments
View Download 0.305 a.77.1 DEATH domain
View Download 0.303 a.16.1 S15/NS1 RNA-binding domain
View Download 0.302 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.301 f.13.1 Family A G protein-coupled receptor-like
View Download 0.300 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.298 a.4.8 Ribosomal protein S18
View Download 0.298 f.15.1 Small-conductance potassium channel
View Download 0.297 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.297 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.290 a.16.1 S15/NS1 RNA-binding domain
View Download 0.284 d.222.1 YbaB-like
View Download 0.283 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.283 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.280 i.1.1 Ribosome and ribosomal fragments
View Download 0.272 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.266 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.266 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.263 a.2.3 Chaperone J-domain
View Download 0.260 a.3.1 Cytochrome c
View Download 0.257 f.15.1 Small-conductance potassium channel
View Download 0.253 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.251 a.2.3 Chaperone J-domain
View Download 0.248 g.57.1 Serine proteinase inhibitor lekti
View Download 0.247 a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.243 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.243 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.241 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.241 a.157.1 Skp1 dimerisation domain-like
View Download 0.240 a.157.1 Skp1 dimerisation domain-like
View Download 0.227 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.225 a.65.1 Annexin
View Download 0.223 a.16.1 S15/NS1 RNA-binding domain
View Download 0.222 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.221 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.216 a.7.6 Ribosomal protein S20
View Download 0.215 a.157.1 Skp1 dimerisation domain-like
View Download 0.208 a.4.1 Homeodomain-like
View Download 0.207 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.207 a.4.1 Homeodomain-like
View Download 0.206 f.30.1 Photosystem I reaction center subunit X, PsaK
View Download 0.206 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.204 a.64.1 Saposin
View Download 0.204 a.4.5 "Winged helix" DNA-binding domain
View Download 0.204 a.4.5 "Winged helix" DNA-binding domain

Predicted functions:

Term Confidence Notes
receptor activity 1.64987101746707 bayes_pls_golite062009
transmembrane receptor activity 1.34503183418293 bayes_pls_golite062009
binding 1.08525898490902 bayes_pls_golite062009
protein binding 0.669091045213589 bayes_pls_golite062009
signal transducer activity 0.499118819144462 bayes_pls_golite062009
molecular transducer activity 0.499118819144462 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [63-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPNILDHNIM LVNTNATIPK KEQTDFEVIS PTKQTQVDED CKKGLYHIEN AGNLIELQAK  60
   61 CWKVVGNIEI SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.154902
Match: 1h6uA_
Description: Internalin H
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [135-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYSGSLIDLG LIREIEGDLI IKNNKHIFRI QGYNLESLGK LELDSLTSFV SLDFPALKEV  60
   61 ETVDWRVLPI LSSVVINGNI KKIKNIIISD TALTSIDYFN NVKKVDIFNI NNNRFLENLF 120
  121 ASLESVTKQL TVHSNAKELE LDLSNLHTVE NMTIKDVSEI KLAKLSSVNS SLEFIENQFS 180
  181 SLELPLLAKV QGTLGLIDNK NLKKLNFSNA TDIQGGLMIA NNTELAKIDF FPKLRQIGGA 240
  241 IYFEGSFDKI DLPELKLVKG SAYIKSSSEE LNCEEFTSPK AGRSIIRGGK IECTSGMKSK 300
  301 MLNVDEEGNV LGKQET

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.0
Match: 1jl5A_
Description: Leucine rich effector protein YopM
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [451-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNDNGKKEKG KNGAKSQGSS KKMENSAPKN IFIDAFKMSV YAVFTVLFSI IF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle