YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: FOB1
Organism: Saccharomyces cerevisiae
Length: 566 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FOB1.

Description E-value Query
Range
Subject
Range
gi|2331297, gi|3... - gi|3122096|sp|O13329.1|FOB1_YEAST RecName: Full=DNA replication fork-blocking protein FOB1, gi|23312...
0.0 [1..566] [1..566]

Back

Predicted Domain #1
Region A:
Residues: [1-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKPRYNDVL FDDDDSVPSE SVTRKSQRRK ATSPGESRES SKDRLLILPS MGESYTEYVD  60
   61 SYLNLELLER GERETPIFLE SLTRQLTQKI YELIKTKSLT ADTLQQISDK YDGVVAENKL 120
  121 LFLQRQYYVD DEGNVRDGRN NDKIYCEPKH VYDMVMATHL MNKHLRGKTL HSFLFSHFAN 180
  181 ISHAIIDWVQ QFCSKCNKKG KIKPLKEYKR PDMYDKLLPM ERIHIEVFEP FNGEAIEGKY 240
  241 SYVLLCRDYR SSFMWLLPLK STKFKHLIPV VSSLFLTFAR VPIFVTSSTL DKDDLYDICE 300
  301 EIASKYGLRI GLGLKSSARF HTGGILCIQY ALNSYKKECL ADWGKCLRYG PYRFNRRRNK 360
  361 RTKRKPVQVL LSEVPGHNAK FETKRERVIE NTYSRNMFKM AGGKGLIYLE DVNTFALANE 420
  421 ADNSCNNNGI LHNNNIGNDN FEEEVQKQFD LTEKNYIDEY DDLAHDSSEG EFEPNTLTPE 480
  481 EKPPHNVDED RIESTGVAAP MQGTEEPEKG DQKESDGASQ VDQSVEITRP ETSYYQTLES 540
  541 PSTKRQKLDQ QGNGDQTRDF GTSMEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [131-484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEGNVRDGRN NDKIYCEPKH VYDMVMATHL MNKHLRGKTL HSFLFSHFAN ISHAIIDWVQ  60
   61 QFCSKCNKKG KIKPLKEYKR PDMYDKLLPM ERIHIEVFEP FNGEAIEGKY SYVLLCRDYR 120
  121 SSFMWLLPLK STKFKHLIPV VSSLFLTFAR VPIFVTSSTL DKDDLYDICE EIASKYGLRI 180
  181 GLGLKSSARF HTGGILCIQY ALNSYKKECL ADWGKCLRYG PYRFNRRRNK RTKRKPVQVL 240
  241 LSEVPGHNAK FETKRERVIE NTYSRNMFKM AGGKGLIYLE DVNTFALANE ADNSCNNNGI 300
  301 LHNNNIGNDN FEEEVQKQFD LTEKNYIDEY DDLAHDSSEG EFEPNTLTPE EKPP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.37
Match: 1k6yA
Description: N-terminal Zn binding domain of HIV integrase; Retroviral integrase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
exonuclease activity 2.69169803889636 bayes_pls_golite062009
nuclease activity 2.63308556411438 bayes_pls_golite062009
3'-5'-exoribonuclease activity 2.43802973446357 bayes_pls_golite062009
transcription regulator activity 2.22832306273638 bayes_pls_golite062009
ribonuclease activity 2.21640837000075 bayes_pls_golite062009
nucleic acid binding 2.15202443486046 bayes_pls_golite062009
DNA binding 1.88388568255929 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.66403897673963 bayes_pls_golite062009
DNA polymerase activity 1.57871253412659 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.54823157746404 bayes_pls_golite062009
DNA-directed DNA polymerase activity 1.44766638837068 bayes_pls_golite062009
binding 1.42021256417703 bayes_pls_golite062009
transcription factor activity 1.18792852183348 bayes_pls_golite062009
nucleotidyltransferase activity 1.16950079926796 bayes_pls_golite062009
catalytic activity 1.16880796007849 bayes_pls_golite062009
hydrolase activity 1.02227964399726 bayes_pls_golite062009
3'-5' exonuclease activity 1.01792206204118 bayes_pls_golite062009
exoribonuclease activity 0.985835839433199 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.91438167081716 bayes_pls_golite062009
deoxyribonuclease activity 0.819269466567015 bayes_pls_golite062009
endonuclease activity 0.591008475846166 bayes_pls_golite062009
0.300511724300705 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.244405458380391 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.152950127352174 bayes_pls_golite062009
transcription activator activity 0.0924765766526223 bayes_pls_golite062009
protein binding 0.0799098348667361 bayes_pls_golite062009
structure-specific DNA binding 0.056513663571923 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [485-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNVDEDRIES TGVAAPMQGT EEPEKGDQKE SDGASQVDQS VEITRPETSY YQTLESPSTK  60
   61 RQKLDQQGNG DQTRDFGTSM EL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle