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View Structure Prediction Details

Protein: LYS14
Organism: Saccharomyces cerevisiae
Length: 790 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LYS14.

Description E-value Query
Range
Subject
Range
gi|551278 - gi|551278|emb|CAA54550.1| LYS14 protein [Saccharomyces cerevisiae]
0.0 [1..790] [1..790]
YCUA_SCHPO - Uncharacterized transcriptional regulatory protein C965.10 OS=Schizosaccharomyces pombe (strain 972 ...
SPCC965.10 - transcription factor
1.0E-84 [140..545] [2..338]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
4.0E-52 [4..423] [679..1115]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
2.0E-35 [5..403] [767..1176]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-35 [100..437] [3..347]
gi|40217297, gi|... - gi|4808164|emb|CAB42795.1| largest subunit of the RNA polymerase II complex [Drosophila guanche], gi...
9.0E-35 [10..353] [1498..1887]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFESVNLDEN SPEDRELAKV LSPPGSYLSP ASLDSGSSFT NSGTSTSCFE PKNNLPSLSF  60
   61 LNARAGSLGG IFNHKQMTSP SNSNIGGENV ESTTSSNDGS NENAGHPTTS EQDQNADHPT 120
  121 ISQADDNGHS SLTPNPAVTS TVTDKKGNTV KR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [153-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYSRNGCSEC KRRRMKCDET KPTCWQCARL NRQCVYVLNP KNKKRRTSNA QRVKEFRKHS  60
   61 TSLDNDHNNA RKRQHSSCKA E

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.619789
Match: PF00172
Description: Fungal Zn(2)-Cys(6) binuclear cluster domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.03201524223606 bayes_pls_golite062009
sequence-specific DNA binding 1.87955444697212 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.86200506906385 bayes_pls_golite062009
transcription activator activity 0.915626626047549 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [234-790]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKKVRQNLS EDTTDPKPIT DNGKNVPLDE IESLEIPNLD LTTTMNGYDV NLLMQNLNDM  60
   61 VNMKLHDSYL LNEELKGLDL PDLDIPELLP ASNVNSSVPI SFLVNNVITF NTKLSSFKLG 120
  121 GIHDKYLKIF YYDCLDSIAP FFQNQGNPLR DILLSFAKNE AYLLSSILAT GASIAYRKSN 180
  181 NLEDERNYCA YLSHCLSLLG EQFKNESNVL NRIEPIILTV IMLAWDCIYS MNSQWRSHLK 240
  241 GVTDLFKKIN AGNSSKVLNV AKCWFKVMET FASISTVFGG SLIDNNDLDA IFDPYDYQYV 300
  301 DSLKFLNIMT PLNEFNLLRG HKEDFDLVIK EVFKSLNTIR STEKNYFSKE EGLFTKKLDY 360
  361 LLLSSQTSSE KSKDQISYFN TQKILVEIDK QLDYEFIDKS GIIPSDNQSH PRISNIHDNA 420
  421 IDMVTLKNGE EVAISWYDIS HQTQVLSFLL IVLLKLLGMP KESSTIQQVV KKIMSFFKFL 480
  481 DSDSPPQNSR TCYSNFAVLI AGLNAMDEET RAIVKRYYKI NGGKFQKLTE HNLNRLEKVW 540
  541 YGKNQNYRLE EQDVLTW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [355-553]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHDKYLKIFY YDCLDSIAPF FQNQGNPLRD ILLSFAKNEA YLLSSILATG ASIAYRKSNN  60
   61 LEDERNYCAY LSHCLSLLGE QFKNESNVLN RIEPIILTVI MLAWDCIYSM NSQWRSHLKG 120
  121 VTDLFKKINA GNSSKVLNVA KCWFKVMETF ASISTVFGGS LIDNNDLDAI FDPYDYQYVD 180
  181 SLKFLNIMTP LNEFNLLRG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [554-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKEDFDLVIK EVFKSLNTIR STEKNYFSKE EGLFTKKLDY LLLSSQTSSE KSKDQISYFN  60
   61 TQKILVEIDK QLDYEFIDKS GIIPSD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [640-790]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQSHPRISNI HDNAIDMVTL KNGEEVAISW YDISHQTQVL SFLLIVLLKL LGMPKESSTI  60
   61 QQVVKKIMSF FKFLDSDSPP QNSRTCYSNF AVLIAGLNAM DEETRAIVKR YYKINGGKFQ 120
  121 KLTEHNLNRL EKVWYGKNQN YRLEEQDVLT W

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle