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View Structure Prediction Details

Protein: YRB1
Organism: Saccharomyces cerevisiae
Length: 201 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRB1.

Description E-value Query
Range
Subject
Range
RBP2_MOUSE - E3 SUMO-protein ligase RanBP2 OS=Mus musculus GN=Ranbp2 PE=1 SV=1
6.0E-59 [2..200] [2078..2282]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
1.0E-58 [2..200] [2241..2445]
RANBP2 - RAN binding protein 2
1.0E-58 [2..200] [2241..2445]
RBP2_BOVIN - E3 SUMO-protein ligase RanBP2 (Fragment) OS=Bos taurus GN=RANBP2 PE=2 SV=2
9.0E-56 [2..200] [106..310]
gi|190405019 - gi|190405019|gb|EDV08286.1| ran-specific GTPase-activating protein 1 [Saccharomyces cerevisiae RM11-...
YRB1 - Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated pr...
gi|151941991 - gi|151941991|gb|EDN60347.1| Ran binder protein [Saccharomyces cerevisiae YJM789]
YRB1_YEAST - Ran-specific GTPase-activating protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
gi|207346872 - gi|207346872|gb|EDZ73234.1| YDR002Wp-like protein [Saccharomyces cerevisiae AWRI1631]
2.0E-55 [1..201] [1..201]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-53 [3..199] [114..316]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSEDKKPVV DKKEEAAPKP PSSAVFSMFG GKKAEKPETK KDEEDTKEET KKEGDDAPES  60
   61 PDIHFEPVVH LEKVDVKTME EDEEVLYKVR AKLFRFDADA KEWKERGTGD CKFLKNKKTN 120
  121 KVRILMRRDK TLKICANHII APEYTLKPNV GSDRSWVYAC TADIAEGEAE AFTFAIRFGS 180
  181 KENADKFKEE FEKAQEINKK A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 346.512579
Match: 1rrpB_
Description: Nuclear pore complex protein Nup358
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.29080729281876 bayes_pls_golite062009
protein binding 2.12168271674167 bayes_pls_golite062009
GTPase regulator activity 1.66986263418539 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.64990514605397 bayes_pls_golite062009
cytoskeletal protein binding 1.28276455823937 bayes_pls_golite062009
small GTPase regulator activity 1.2550809703725 bayes_pls_golite062009
enzyme regulator activity 1.25381967078645 bayes_pls_golite062009
Ran GTPase binding 1.07023555877478 bayes_pls_golite062009
actin binding 1.07022589084633 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.745321902095093 bayes_pls_golite062009
small GTPase binding 0.721546282992641 bayes_pls_golite062009
GTPase binding 0.70180064264191 bayes_pls_golite062009
transcription regulator activity 0.324566338715835 bayes_pls_golite062009
nucleic acid binding 0.242570396032937 bayes_pls_golite062009
DNA binding 0.136435190086451 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle