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View Structure Prediction Details

Protein: UGA3
Organism: Saccharomyces cerevisiae
Length: 528 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UGA3.

Description E-value Query
Range
Subject
Range
UGA3_YEAST - Transcriptional activator protein UGA3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=U...
UGA3 - Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes...
0.0 [1..528] [1..528]
YCUA_SCHPO - Uncharacterized transcriptional regulatory protein C965.10 OS=Schizosaccharomyces pombe (strain 972 ...
SPCC965.10 - transcription factor
0.0 [9..526] [13..522]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-51 [2..268] [76..315]
gi|7688277 - gi|7688277|emb|CAB89829.1| PRO1 protein [Sordaria brevicollis]
6.0E-35 [2..182] [37..214]
gi|8218220 - gi|8218220|emb|CAB52588.2| PRO1 protein [Sordaria macrospora]
7.0E-34 [2..182] [37..213]
PRO1_NEUCR - Transcriptional regulatory protein pro-1 OS=Neurospora crassa GN=pro-1 PE=2 SV=1
PRO1_NEUCR - Transcriptional regulatory protein pro1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 7...
3.0E-30 [2..182] [38..214]
ALCR_EMENI - Regulatory protein alcR OS=Emericella nidulans GN=alcR PE=1 SV=2
ALCR_EMENI - Regulatory protein alcR OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 ...
2.0E-28 [9..179] [4..209]

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Predicted Domain #1
Region A:
Residues: [1-58]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYGVEKLKL KYSKHGCITC KIRKKRCSED KPVCRDCRRL SFPCIYISES VDKQSLKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.201249
Match: 1pyiA_
Description: PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
sequence-specific DNA binding 2.98081393153291 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
transcription activator activity 2.24483536326713 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [59-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKADIQHQLI SKKRKHAPDS AQKAAVATRT RRVGSDEQDN QVYLSKPLED CISQKLDSMG  60
   61 LQLYNYYRSH LANIISIAPM NQNYYLNIFL PMAHENDGIL FAILAWSANH LSISSSNELR 120
  121 KDEIFVNLAN KYTYMSLSHL KTNEGSSACA KLGFLYSLAQ ILILCGSEIC QGDVKFWKIL 180
  181 LNIGKNLIEN HVGKDVSRIL TTTTEEPSLE ERIIFPNFNS VVKYWLIVNF IYHDILNFNT 240
  241 TSFPIEQYEK FFQRDQNSLP SSANFIESID SPIEEIDPLI GINKPILLLL GQVTNLTRFL 300
  301 QTMEQEEMLE HGDKILSLQV EIYKLQPSLM ALEHLDDEKK FYYLELFEIM KISTLMFFQL 360
  361 TLLKIDKDSL ELQILRNKLD SKLDKVIGTF LEGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [453-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LCFPLFIYGV CIQVEDMEKK IDLEAKFDDI LKRYKCYNFQ NARLLIRKIW QNEADGISEH  60
   61 DLVHMIDELD YNINFA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.888 0.193 regulation of transcription from RNA polymerase II promoter a.74.1 Cyclin-like

Predicted Domain #4
Region A:
Residues: [395-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEKKFYYLEL FEIMKISTLM FFQLTLLKID KDSLELQILR NKLDSKLDKV IGTFLEGSLC  60
   61 FPLFIYGVCI QVEDMEKKID LEAKFDDILK RYKCYNFQNA RLLIRKIWQN EADGISEHDL 120
  121 VHMIDELDYN INFA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle