YRC Public Data Repository - Protein Structure Prediction

Protein:	MCH1
Organism:	Saccharomyces cerevisiae
Length:	486 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCH1.

Description	E-value	Query Range	Subject Range
VGLU2_RAT - Vesicular glutamate transporter 2 OS=Rattus norvegicus GN=Slc17a6 PE=1 SV=1	8.0E-54	[20..481]	[63..503]
ANTR1_ARATH - Sodium-dependent phosphate transport protein 1, chloroplastic OS=Arabidopsis thaliana GN=ANTR1 PE=1 ...	2.0E-53	[10..460]	[84..501]
ENSPTRT00000047022 - null SLC17A6 - solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	9.0E-53	[20..481]	[63..503]
gi\|16077317, gi\|... - gi\|2632534\|emb\|CAB12042.1\| ycbE [Bacillus subtilis subsp. subtilis str. 168], gi\|16077317\|ref\|NP_388... GUDP_BACSU - Probable glucarate transporter OS=Bacillus subtilis GN=gudP PE=3 SV=1	1.0E-50	[16..485]	[7..443]
CG15096-PA, FBpp... - This gene is referred to in FlyBase by the symbol Dmel\CG15096 (CG15096, FBgn0034394). It is a prote... gi\|220952136 - gi\|220952136\|gb\|ACL88611.1\| CG15096-PA [synthetic construct]	2.0E-50	[21..475]	[30..464]
GUDP_PSEPU - Probable glucarate transporter OS=Pseudomonas putida GN=gudP PE=3 SV=1	3.0E-50	[24..485]	[7..434]
gi\|206710031, gi... - gi\|207858228\|ref\|YP_002244879.1\| glucarate transporter [Salmonella enterica subsp. enterica serovar ... gi\|204322464, gi... - gi\|204928142\|ref\|ZP_03219342.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Javi... lcl\|NC_016856.1_... - [gene=gudT] [protein=putative D-glucarate permease] [protein_id=YP_005239079.1] [location=complement... gi\|205273686, gi... - gi\|205353905\|ref\|YP_002227706.1\| glucarate transporter [Salmonella enterica subsp. enterica serovar ... gi\|197261896, gi... - gi\|197261896\|ref\|ZP_03161970.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Sain... gi\|199605749, gi... - gi\|200388651\|ref\|ZP_03215263.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Virc... gi\|194737540, gi... - gi\|194737540\|ref\|YP_002115914.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Sch... gi\|197212076, gi... - gi\|197248373\|ref\|YP_002147872.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Ago... gi\|194449069, gi... - gi\|194449069\|ref\|YP_002046931.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Hei... gi\|194458870, gi... - gi\|194472506\|ref\|ZP_03078490.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Kent... gi\|205342885, gi... - gi\|205342885\|gb\|EDZ29649.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Weltevre... gi\|194403131, gi... - gi\|194444468\|ref\|YP_002042213.1\| glucarate permease [Salmonella enterica subsp. enterica serovar New... gi\|205349198, gi... - gi\|205349198\|gb\|EDZ35829.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Hadar st... gi\|168463887, gi... - gi\|195633479\|gb\|EDX51893.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Newport ... gi\|62181471, gi\|... - gi\|62181471\|ref\|YP_217888.1\| MFS superfamily, D-glucarate permease [Salmonella enterica subsp. enter... gi\|168236008, gi... - gi\|197290713\|gb\|EDY30067.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Schwarze... gi\|168242723, gi... - gi\|205338002\|gb\|EDZ24766.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Heidelbe... gi\|167993454, gi... - gi\|205328457\|gb\|EDZ15221.1\| glucarate permease [Salmonella enterica subsp. enterica serovar 4,[5],12... gi\|168231053, gi... - gi\|205334420\|gb\|EDZ21184.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Kentucky... gi\|205324865, gi... - gi\|205324865\|gb\|EDZ12704.1\| glucarate permease [Salmonella enterica subsp. enterica serovar Saintpau... gi\|16766268, gi\|... - gi\|16766268\|ref\|NP_461883.1\| putative D-glucarate permease [Salmonella typhimurium LT2], gi\|16421513...	5.0E-50	[23..485]	[14..445]

Back

Predicted Domain #1

Region A:
Residues: [1-222]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLSKVEHYL SYHTRLLLPH VLSLQSSHRV AYIFSLLSAV STGFITLISL YSQPWQKHLN  60
   61 YSSWQINTIA SMTNLGMYLT PPILGMIADS HGPITLSLLA IIGFIPSYSY LAYVFNHPEL 120
  121 SLGGNGDSSF NLSIICFVFI GISTSALYFS ALLTCTKLYP HTKLLSISLP TTCYGISSVV 180
  181 GSQLLRIKWF WSSNASSSSS NSDLNLGRVF QTFALVYVVI GL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [267-486]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFTQTMLRIF SDPVTYILAV SILLSLGPLE MFIANMGSLT NLLVQLDAPT LSTKLLSTYA  60
   61 LSSTFTRLLT GIVADFFAKK KISIKWILLT FLSLGVCAQL FLLKMTSSAS PWGLVPTGSL 120
  121 VGIVYGGLFT VYPTLVLLVW GERSFGTVYG SLLIAPAIGS MIFCMLYAKF YDSRCMSGGG 180
  181 DLRNPSCISA VYKYSSIAFV VSAVLSAVVF WKLKSRKLRI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.522879
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
binding	0.805286077372817	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [223-266]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAWIATSVVS LLHFNEEQDN QKRLDDQTDV EQSPLLERSN HVQE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.522879
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: