YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RRP43
Organism: Saccharomyces cerevisiae
Length: 394 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRP43.

Description E-value Query
Range
Subject
Range
RRP43_YEAST - Exosome complex component RRP43 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRP43 PE...
RRP43 - Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the n...
0.0 [1..394] [1..394]
RRP43_SCHPO - Exosome complex component rrp43 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rrp43 PE=3...
SPBC17D1.03c - exosome subunit Rrp43
7.0E-11 [12..250] [7..184]

Back

Predicted Domain #1
Region A:
Residues: [1-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAESTTLETI EIHPITFPPE VLARISPELS LQRHLSLGIR PCLRKYEEFR DVAIENNTLS  60
   61 RYADAGNIDT KNNILGSNVL KSGKTIVITS ITGGIIEETS AAIKDLDDFG EEELFEVTKE 120
  121 EDIIANYASV YPVVEVERGR VGACTDEEMT ISQKLHDSIL HSRILPKKAL KVKAGVRSAN 180
  181 EDGTFSVLYP DELEDDTLNE TNLKMKRKWS YVLYAKIVVL SRTGPVFDLC WNSLMYALQS 240
  241 VKLPRAFIDE RASDLRMTIR TRGRSATIRE TYEIICD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 42.026872
Match: PF01138
Description: 3' exoribonuclease family, domain 1

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
ribonuclease activity 7.23127959979732 bayes_pls_golite062009
exoribonuclease activity 7.1818107582098 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 7.15162444368945 bayes_pls_golite062009
3'-5'-exoribonuclease activity 6.07082095113089 bayes_pls_golite062009
3'-5' exonuclease activity 3.97196194079029 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3.56720447478991 bayes_pls_golite062009
exonuclease activity 3.17253431625181 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.74672075915955 bayes_pls_golite062009
RNA binding 1.95606366707311 bayes_pls_golite062009
structural constituent of ribosome 1.71911386517518 bayes_pls_golite062009
structural molecule activity 1.54100243929123 bayes_pls_golite062009
hydrolase activity 1.48006994106758 bayes_pls_golite062009
transcription regulator activity 1.21692959363145 bayes_pls_golite062009
nucleic acid binding 1.06421277984865 bayes_pls_golite062009
mRNA binding 1.04070984651466 bayes_pls_golite062009
binding 0.958185654055629 bayes_pls_golite062009
DNA binding 0.849730288865394 bayes_pls_golite062009
catalytic activity 0.832312651473597 bayes_pls_golite062009
nuclease activity 0.455660692064928 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [278-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTKSVPLMIN AKNIAFASNY GIVELDPECQ LQNSDNSEEE EVDIDMDKLN TVLIADLDTE  60
   61 AEETSIHSTI SILAAPSGNY KQLTLVGGGA KITPEMIKRS LLLSRVRADD LSTRFNI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 14.455932
Match: PF03725
Description: 3' exoribonuclease family, domain 2

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle