YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: SRD1
Organism: Saccharomyces cerevisiae
Length: 221 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRD1.

Description E-value Query
Range
Subject
Range
SRD1_YEAST - Pre-rRNA-processing protein SRD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRD1 PE...
SRD1 - Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; s...
2.0E-53 [1..221] [1..221]
gi|5882288 - gi|5882288|gb|AAD55267.1|AF179425_1 transcription factor GATA-6 [Mus musculus]
2.0E-39 [47..220] [179..343]
gi|18959228, gi|... - gi|18959228|ref|NP_579827.1| GATA binding protein 3 [Rattus norvegicus], gi|149021023|gb|EDL78630.1|...
7.0E-39 [5..218] [166..367]
GATA3 - GATA binding protein 3
2.0E-38 [5..218] [166..366]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-37 [5..218] [166..367]

Back

Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYNNYDNSG SSFLTRVVKK SDMEKTLLLN REIDDWKSND KKKAYKERGR VYASCSFIEV  60
   61 SFSQIRAVDV EKKIENAEQL RDLTRNIVKN KTSSLNEITP SKNRVTSACN SERRTTSQEA 120
  121 NNLEGYHSCA QGTSRSASI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKKYSKKTTS RPKREKRQTI LPNGEIKECS KCKDTWTIQW RSGPDQNREL CSPCGLAYGK  60
   61 RLKKENEKKR QAADKRIDRN NP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.045757
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.90545037627165 bayes_pls_golite062009
DNA binding 2.60187443597685 bayes_pls_golite062009
binding 2.3712591616364 bayes_pls_golite062009
nucleic acid binding 2.37049966873591 bayes_pls_golite062009
transcription factor activity 2.06400766265838 bayes_pls_golite062009
protein binding 1.16334132659733 bayes_pls_golite062009
sequence-specific DNA binding 1.09234758156492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.01709689122918 bayes_pls_golite062009
transcription activator activity 0.84971806234869 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 0.66439028392158 bayes_pls_golite062009
transcription factor binding 0.66367552914256 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.10642958544072 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009
transcription cofactor activity 0.06728167026678 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle