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View Structure Prediction Details

Protein: SRD1
Organism: Saccharomyces cerevisiae
Length: 221 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRD1.

Description E-value Query
Range
Subject
Range
SRD1_YEAST - Pre-rRNA-processing protein SRD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRD1 PE...
SRD1 - Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; s...
2.0E-53 [1..221] [1..221]
gi|5882288 - gi|5882288|gb|AAD55267.1|AF179425_1 transcription factor GATA-6 [Mus musculus]
2.0E-39 [47..220] [179..343]
gi|18959228, gi|... - gi|18959228|ref|NP_579827.1| GATA binding protein 3 [Rattus norvegicus], gi|149021023|gb|EDL78630.1|...
7.0E-39 [5..218] [166..367]
GATA3 - GATA binding protein 3
2.0E-38 [5..218] [166..366]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-37 [5..218] [166..367]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYNNYDNSG SSFLTRVVKK SDMEKTLLLN REIDDWKSND KKKAYKERGR VYASCSFIEV  60
   61 SFSQIRAVDV EKKIENAEQL RDLTRNIVKN KTSSLNEITP SKNRVTSACN SERRTTSQEA 120
  121 NNLEGYHSCA QGTSRSASI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKKYSKKTTS RPKREKRQTI LPNGEIKECS KCKDTWTIQW RSGPDQNREL CSPCGLAYGK  60
   61 RLKKENEKKR QAADKRIDRN NP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.045757
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.90545037627165 bayes_pls_golite062009
DNA binding 2.60187443597685 bayes_pls_golite062009
binding 2.3712591616364 bayes_pls_golite062009
nucleic acid binding 2.37049966873591 bayes_pls_golite062009
transcription factor activity 2.06400766265838 bayes_pls_golite062009
protein binding 1.16334132659733 bayes_pls_golite062009
sequence-specific DNA binding 1.09234758156492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.01709689122918 bayes_pls_golite062009
transcription activator activity 0.84971806234869 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 0.66439028392158 bayes_pls_golite062009
transcription factor binding 0.66367552914256 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.10642958544072 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009
transcription cofactor activity 0.06728167026678 bayes_pls_golite062009

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