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View Structure Prediction Details

Protein: LSB5
Organism: Saccharomyces cerevisiae
Length: 354 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LSB5.

Description E-value Query
Range
Subject
Range
LSB5_YEAST - LAS seventeen-binding protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LSB5 PE=...
LSB5 - Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome prot...
gi|207347367 - gi|207347367|gb|EDZ73561.1| YCL034Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190406412 - gi|190406412|gb|EDV09679.1| LAS seventeen binding protein 5 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..354] [1..354]
SPBC31F10.07 - cortical component Lsb5
LSB5_SCHPO - Protein lsb5 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lsb5 PE=3 SV=1
0.0 [1..354] [1..303]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-71 [172..354] [30..212]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFLSDHPHT AITETIFRIV SSRDYTLEVE LAPLIQLIKA DHNDYNYTVN QEEAARALRK  60
   61 KIKYGNRLQQ SRTLDLLDLF ISQGVKFTVM Y

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.86
Match: 1jwfA
Description: ADP-ribosylation factor binding protein Gga1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 2.2051555354265 bayes_pls_golite062009
binding 2.04296681309629 bayes_pls_golite062009
protein binding 1.8451435695957 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 0.913711498494864 bayes_pls_golite062009
phospholipid binding 0.583709100639576 bayes_pls_golite062009
phosphoinositide binding 0.562042231995162 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [92-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDDKLLQRLR GMATNSENSG SGEKYEPRII KKCAAYAISW LNYITQNNLE NARAYSGLYQ  60
   61 LGQTVKQRYS KSSRSRR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.86
Match: 1jwfA
Description: ADP-ribosylation factor binding protein Gga1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 3.56527129767546 bayes_pls_golite062009
binding 1.9253053687392 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.88822455907721 bayes_pls_golite062009
protein binding 1.65824069417195 bayes_pls_golite062009
phosphoinositide binding 1.30275072241927 bayes_pls_golite062009
phospholipid binding 1.04623877187105 bayes_pls_golite062009
lipid binding 0.447565169704067 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [169-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGGSGGRSN FMDDSADDTL YQSNSLTSAD RLYRIPQINM NKEAPRIRLI ISDALASAVS  60
   61 LQNSLIGLPK GKFSTDDEEA TSKFIQARAI RRKVLRYLQL VTEGEFLGSL IHANDELVAA 120
  121 LTAYDDRSAQ DDSSDESDHG SYDDGIYDEN EQDNSRYIDS ESSEEESLSS YQPSTISNPF 180
  181 GDHNKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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