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View Structure Prediction Details

Protein: DUT1
Organism: Saccharomyces cerevisiae
Length: 147 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DUT1.

Description E-value Query
Range		 Subject
Range
gi|123980576, gi... - gi|61364276|gb|AAX42517.1| dUTP pyrophosphatase [synthetic construct], gi|60820926|gb|AAX36554.1| dU...
gi|21708114, gi|... - gi|7435912|pir||G02777 dUTP diphosphatase (EC 3.6.1.23) - human, gi|60115828|gb|AAX14045.1| dUTP pyr...
 5.0E-49 [4..146] [21..162]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 7.0E-49 [7..146] [1..139]
DUT_RAT - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Rattus norvegicus GN=Dut PE=2 SV=3
 8.0E-49 [2..146] [60..203]
gi|21281687, gi|... - gi|74220093|dbj|BAE31237.1| unnamed protein product [Mus musculus], gi|74142206|dbj|BAE31868.1| unna...
 1.0E-48 [2..146] [17..160]
gi|3046554 - gi|3046554|gb|AAD03407.1| dUTPase homolog [orf virus strain D1701]
 4.0E-47 [6..147] [6..146]
DUT_ARATH - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Arabidopsis thaliana GN=DUT PE=1 SV=1
 3.0E-46 [5..146] [25..165]
DUT_SOLLC - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Solanum lycopersicum PE=2 SV=1
 7.0E-46 [6..146] [29..168]

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Predicted Domain #1
Region A:
Residues: [1-147] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTATSDKVLK IQLRSASATV PTKGSATAAG YDIYASQDIT IPAMGQGMVS TDISFTVPVG  60
   61 TYGRIAPRSG LAVKNGIQTG AGVVDRDYTG EVKVVLFNHS QRDFAIKKGD RVAQLILEKI 120
  121 VDDAQIVVVD SLEESARGAG GFGSTGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 154.626727
Match: 1dud__
Description: Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleoside-triphosphate diphosphatase activity 5.64898078077484 bayes_pls_golite062009
dUTP diphosphatase activity 5.62861923551608 bayes_pls_golite062009
hydrolase activity 1.8120510491809 bayes_pls_golite062009
catalytic activity 1.71668532866244 bayes_pls_golite062009
pyrophosphatase activity 1.43042083356989 bayes_pls_golite062009
binding 1.21193927389015 bayes_pls_golite062009
peroxisome proliferator activated receptor binding 1.01014631701573 bayes_pls_golite062009
pyrimidine deoxyribonucleotide binding 0.378438138772693 bayes_pls_golite062009
pyrimidine nucleotide binding 0.26077271033521 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle