YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM12
Organism:	Saccharomyces cerevisiae
Length:	109 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM12.

Description	E-value	Query Range	Subject Range
gi\|190408748 - gi\|190408748\|gb\|EDV12013.1\| mitochondrial regulator of splicing 5 [Saccharomyces cerevisiae RM11-1a] gi\|151946485 - gi\|151946485\|gb\|EDN64707.1\| protein of the inner mitochondrial membrane [Saccharomyces cerevisiae YJ... TIM12 - Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM2... TIM12_YEAST - Mitochondrial import inner membrane translocase subunit TIM12 OS=Saccharomyces cerevisiae (strain AT...	1.0E-39	[1..109]	[1..109]
gi\|5107178, gi\|7... - gi\|74096149\|ref\|NP_001027735.1\| small zinc finger-like protein [Ciona intestinalis], gi\|5107178\|gb\|A...	2.0E-24	[13..97]	[3..85]
TIM10_SCHPO - Mitochondrial import inner membrane translocase subunit tim10 OS=Schizosaccharomyces pombe (strain 9... tim10 - Tim9-Tim10 complex subunit Tim10	5.0E-24	[9..86]	[8..84]
gi\|109106266, gi... - gi\|109106268\|ref\|XP_001102305.1\| PREDICTED: similar to translocase of inner mitochondrial membrane 1... tr\|G1SF82\|G1SF82... - pep:novel chromosome:oryCun2:1:190612228:190615383:-1 gene:ENSOCUG00000001338 transcript:ENSOCUT0000... CCDS7959.1_1 - null TIM10_RAT - Mitochondrial import inner membrane translocase subunit Tim10 OS=Rattus norvegicus GN=Timm10 PE=3 SV... gi\|149758105 - gi\|149758105\|ref\|XP_001498316.1\| PREDICTED: similar to Mitochondrial import inner membrane transloca... TIMM10 - translocase of inner mitochondrial membrane 10 homolog (yeast) tr\|G3HRI3\|G3HRI3... - Mitochondrial import inner membrane translocase subunit Tim10 OS=Cricetulus griseus GN=I79_013455 PE... TIM10_MOUSE - Mitochondrial import inner membrane translocase subunit Tim10 OS=Mus musculus GN=Timm10 PE=1 SV=1 gi\|55635935, gi\|... - gi\|55635935\|ref\|XP_508433.1\| PREDICTED: translocase of inner mitochondrial membrane 10 homolog isofo... ENSCJAT00000017183 - null	2.0E-23	[13..97]	[3..85]
gi\|7305575, gi\|5... - gi\|7305575\|ref\|NP_038927.1\| translocase of inner mitochondrial membrane 13 homolog a [Mus musculus],...	4.0E-23	[13..97]	[3..85]
gi\|5107172 - gi\|5107172\|gb\|AAD39998.1\|AF150092_1 small zinc finger-like protein [Drosophila melanogaster]	4.0E-23	[13..96]	[8..91]
tin-10 - status:Confirmed UniProt:Q9Y0V6 protein_id:CAC70139.1	1.0E-22	[14..97]	[3..85]
TIM10_PICSO - Mitochondrial import inner membrane translocase subunit Tim10 OS=Pichia sorbitophila (strain ATCC MY... TIM10_MILFA, TIM... - Mitochondrial import inner membrane translocase subunit Tim10 OS=Pichia farinosa GN=TIM10 PE=3 SV=1,...	2.0E-22	[12..86]	[9..82]
TIM10_ARATH - Mitochondrial import inner membrane translocase subunit TIM10 OS=Arabidopsis thaliana GN=TIM10 PE=1 ...	1.0E-20	[14..83]	[10..78]

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Predicted Domain #1

Region A:
Residues: [1-109]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFFLNSLRG NQEVSQEKLD VAGVQFDAMC STFNNILSTC LEKCIPHEGF GEPDLTKGEQ  60
   61 CCIDRCVAKM HYSNRLIGGF VQTRGFGPEN QLRHYSRFVA KEIADDSKK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	5.207608
Match:	PF02953
Description:	Tim10/DDP family zinc finger

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
protein transporter activity	3.96569591038426	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	3.6132784640414	bayes_pls_golite062009
macromolecule transmembrane transporter activity	3.6132784640414	bayes_pls_golite062009
protein transmembrane transporter activity	3.05578860381335	bayes_pls_golite062009
binding	3.05274001657604	bayes_pls_golite062009
transporter activity	2.98936530239986	bayes_pls_golite062009
substrate-specific transporter activity	2.87815769573142	bayes_pls_golite062009
transmembrane transporter activity	1.67782980643723	bayes_pls_golite062009
protein binding	1.54231655177329	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.42890247609405	bayes_pls_golite062009
primary active transmembrane transporter activity	1.15847548838424	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.15316743403707	bayes_pls_golite062009
active transmembrane transporter activity	1.10003802565492	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: