YRC Public Data Repository - Protein Structure Prediction

Protein:	ETR1
Organism:	Saccharomyces cerevisiae
Length:	380 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ETR1.

Description	E-value	Query Range	Subject Range
gi\|15234529, gi\|... - pir\|\|T05166 quinone reductase homolog F18E5.200 - Arabidopsis thaliana, gi\|7268955\|emb\|CAB81265.1\| p...	2.0E-83	[20..377]	[1..323]
gi\|15155807, gi\|... - gi\|15888165\|ref\|NP_353846.1\| hypothetical protein AGR_C_1508 [Agrobacterium tumefaciens str. C58], g... gi\|25282962 - pir\|\|F97459 probable quinone oxidoreductase [imported] - Agrobacterium tumefaciens (strain C58, Cere...	4.0E-82	[7..376]	[9..344]
gi\|4378174 - gi\|4378174\|gb\|AAD19419.1\| unknown [Zymomonas mobilis] gi\|56552668, gi\|... - gi\|56552668\|ref\|YP_163507.1\| NADPH:quinone oxidoreductase [Zymomonas mobilis subsp. mobilis ZM4], gi...	9.0E-82	[19..377]	[1..324]
ADH5_SACPS - Alcohol dehydrogenase 5 OS=Saccharomyces pastorianus GN=ADH5 PE=3 SV=1 gi\|190408701 - gi\|190408701\|gb\|EDV11966.1\| alcohol dehydrogenase isoenzyme V [Saccharomyces cerevisiae RM11-1a] ADH5 - Alcohol dehydrogenase isoenzyme V; involved in ethanol production ADH5_YEAST - Alcohol dehydrogenase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH5 PE=1 SV=1 gi\|151946534 - gi\|151946534\|gb\|EDN64756.1\| alcohol dehydrogenase isoenzyme V [Saccharomyces cerevisiae YJM789]	1.0E-81	[11..377]	[1..347]
gi\|7248741 - gi\|7248741\|gb\|AAF43645.1\|AF218309_1 alcohol dehydrogenase isozyme 3; Adh3 [Saccharomyces kluyveri]	1.0E-81	[9..377]	[21..369]
gi\|2983768, gi\|1... - gi\|2983768\|gb\|AAC07327.1\| alcohol dehydrogenase [Aquifex aeolicus VF5], gi\|15606558\|ref\|NP_213938.1\|... gi\|7427649 - pir\|\|C70418 probable alcohol dehydrogenase (EC 1.1.1.-) - Aquifex aeolicus	4.0E-81	[20..377]	[1..340]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-80	[19..378]	[1..323]
gi\|11351622 - pir\|\|A82991 probable oxidoreductase PA5234 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|9951543, gi\|1... - gi\|9951543\|gb\|AAG08619.1\|AE004936_2 probable oxidoreductase [Pseudomonas aeruginosa PAO1], gi\|156004... gi\|218774565, gi... - gi\|218894336\|ref\|YP_002443206.1\| putative oxidoreductase [Pseudomonas aeruginosa LESB58], gi\|2187745... gi\|84324062, gi\|... - gi\|84324062\|ref\|ZP_00972127.1\| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreduct...	4.0E-80	[20..377]	[1..322]

Back

Predicted Domain #1

Region A:
Residues: [1-155]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPTFKRYMS SSAHQIPKHF KSLIYSTHEV EDCTKVLSVK NYTPKQDLSQ SIVLKTLAFP  60
   61 INPSDINQLQ GVYPSRPEKT YDYSTDEPAA IAGNEGVFEV VSLPSGSSKG DLKLGDRVIP 120
  121 LQANQGTWSN YRVFSSSSDL IKVNDLDLFS AATVS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [340-380]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRDEIETLTW NTNTTTDEQL LELVKKGITG KGKKKMVVLE W

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.154902
Match:	1qorA_
Description:	Quinone oxidoreductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.62461633437589	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.527946013169731	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	0.33551402794014	bayes_pls_golite062009
malate dehydrogenase activity	0.29197621064275	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.233238483713519	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.19685680097448	bayes_pls_golite062009
chaperone binding	0.165316141886854	bayes_pls_golite062009
nucleic acid binding	0.100470710829263	bayes_pls_golite062009
DNA binding	0.0870043837215047	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	0.00644214957417527	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [156-339]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNGCTGFQLV SDYIDWNSNG NEWIIQNAGT SSVSKIVTQV AKAKGIKTLS VIRDRDNFDE  60
   61 VAKVLEDKYG ATKVISESQN NDKTFAKEVL SKILGENARV RLALNSVGGK SSASIARKLE 120
  121 NNALMLTYGG MSKQPVTLPT SLHIFKGLTS KGYWVTEKNK KNPQSKIDTI SDFIKMYNYG 180
  181 HIIS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.154902
Match:	1qorA_
Description:	Quinone oxidoreductase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: