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View Structure Prediction Details

Protein: RBG1
Organism: Saccharomyces cerevisiae
Length: 369 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBG1.

Description E-value Query
Range
Subject
Range
DRG3_ARATH - Developmentally-regulated G-protein 3 OS=Arabidopsis thaliana GN=DRG3 PE=1 SV=1
1.0E-95 [1..369] [1..368]
gi|194198741, gi... - gi|195569634|ref|XP_002102814.1| GD20106 [Drosophila simulans], gi|194198741|gb|EDX12317.1| GD20106 ...
gi|220949542, gi... - gi|220958466|gb|ACL91776.1| CG6195-PA [synthetic construct], gi|220949542|gb|ACL87314.1| CG6195-PA [...
gi|195353604, gi... - gi|195353604|ref|XP_002043294.1| GM26898 [Drosophila sechellia], gi|194127408|gb|EDW49451.1| GM26898...
CG6195-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6195 (CG6195, FBgn0038723). It is a protein...
6.0E-93 [4..369] [3..363]
DRG2_MOUSE - Developmentally-regulated GTP-binding protein 2 OS=Mus musculus GN=Drg2 PE=1 SV=1
gi|149052834 - gi|149052834|gb|EDM04651.1| rCG32787 [Rattus norvegicus]
6.0E-93 [4..369] [3..364]
gi|114668863 - gi|114668863|ref|XP_001158504.1| PREDICTED: developmentally regulated GTP binding protein 2 isoform ...
DRG2 - developmentally regulated GTP binding protein 2
1.0E-92 [4..369] [3..364]
DRG1_XENLA - Developmentally-regulated GTP-binding protein 1 OS=Xenopus laevis GN=drg1 PE=2 SV=1
2.0E-92 [1..369] [1..367]

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Predicted Domain #1
Region A:
Residues: [1-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTVEKIKA IEDEMARTQK NKATSFHLGQ LKAKLAKLRR ELLTSASSGS GGGAGIGFDV  60
   61 ARTGVASVGF VGFPSVGKST LLSKLTGTES EAAEYEFTTL VTVPGVIRYK GAKIQMLDLP 120
  121 GIIDGAKDGR GRGKQVIAVA RTCNLLFIIL DVNKPLHHKQ IIEKELEGVG IRLNKTPPDI 180
  181 LIKKKEKGGI SITNTVPLTH LGNDEIRAVM SEYRINSAEI AFRCDATVDD LIDVLEASSR 240
  241 RYMPAIYVLN KIDSLSIEEL ELLYRIPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1egaA_
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [269-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVPISSGQDW NLDELLQVMW DRLNLVRIYT KPKGQIPDFT DPVVLRSDRC SVKDFCNQIH  60
   61 KSLVDDFRNA LVYGSSVKHQ PQYVGLSHIL EDEDVVTILK K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.09956015274464 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
DNA binding 1.87765278833074 bayes_pls_golite062009
GTPase activity 1.23010905798386 bayes_pls_golite062009
purine ribonucleotide binding 1.21658213854831 bayes_pls_golite062009
ribonucleotide binding 1.21652144153182 bayes_pls_golite062009
purine nucleotide binding 1.21571071905795 bayes_pls_golite062009
nucleotide binding 1.20347573865566 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
motor activity 0.926612891775441 bayes_pls_golite062009
transcription factor activity 0.682439846757997 bayes_pls_golite062009
cytoskeletal protein binding 0.498311726132348 bayes_pls_golite062009
pyrophosphatase activity 0.219555040684154 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.198256709027213 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.197994873032963 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle