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View Structure Prediction Details

Protein: COX1
Organism: Saccharomyces cerevisiae
Length: 534 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX1.

Description E-value Query
Range
Subject
Range
gi|55975988 - gi|55975988|gb|AAV68252.1| cytochrome oxidase subunit 1-2 [Daucus carota]
655.0 [0..2] [533..4]

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Predicted Domain #1
Region A:
Residues: [1-534]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG NSQLFNVLVV  60
   61 GHAVLMIFFL VMPALIGGFG NYLLPLMIGA TDTAFPRINN IAFWVLPMGL VCLVTSTLVE 120
  121 SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA LHLTSISSLL GAINFIVTTL NMRTNGMTMH 180
  181 KLPLFVWSIF ITAFLLLLSL PVLSAGITML LLDRNFNTSF FEVSGGGDPI LYEHLFWFFG 240
  241 HPEVYILIIP GFGIISHVVS TYSKKPVFGE ISMVYAMASI GLLGFLVWSH HMYIVGLDAD 300
  301 TRAYFTSATM IIAIPTGIKI FSWLATIHGG SIRLATPMLY AIAFLFLFTM GGLTGVALAN 360
  361 ASLDVAFHDT YYVVGHFHYV LSMGAIFSLF AGYYYWSPQI LGLNYNEKLA QIQFWLIFIG 420
  421 ANVIFFPMHF LGINGMPRRI PDYPDAFAGW NYVASIGSFI ATLSLFLFIY ILYDQLVNGL 480
  481 NNKVNNKSVI YNKAPDFVES NTIFNLNTVK SSSIEFLLTS PPAVHSFNTP AVQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 169.0
Match: 1occA
Description: Mitochondrial cytochrome c oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
heme-copper terminal oxidase activity 14.1725811596039 bayes_pls_golite062009
cytochrome-c oxidase activity 13.8542976951523 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 13.8542976951523 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 13.8542976951523 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 7.37127314407573 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 7.21569868255501 bayes_pls_golite062009
oxidoreductase activity 7.16307962729639 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 6.59819712923927 bayes_pls_golite062009
cation transmembrane transporter activity 6.32599750294462 bayes_pls_golite062009
ion transmembrane transporter activity 6.1152058837897 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 5.8923420516615 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.6803770025358 bayes_pls_golite062009
substrate-specific transporter activity 5.45928453313406 bayes_pls_golite062009
catalytic activity 1.95966890211023 bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity 1.51081278400602 bayes_pls_golite062009
electron carrier activity 1.29518639068237 bayes_pls_golite062009
binding 0.89004160546195 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor 0.531607015518545 bayes_pls_golite062009
transporter activity 0.37947088637216 bayes_pls_golite062009
transmembrane transporter activity 0.36572623683433 bayes_pls_golite062009
protein binding 0.358081002328109 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle