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View Structure Prediction Details

Protein: glt-4
Organism: Caenorhabditis elegans
Length: 499 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for glt-4.

Description E-value Query
Range
Subject
Range
gi|114637062 - gi|114637062|ref|XP_508369.2| PREDICTED: solute carrier family 1, member 2 [Pan troglodytes]
444.0 [0..1] [495..170]

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Predicted Domain #1
Region A:
Residues: [1-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKLSKENLL LLFTVLGVVV GIGLGFSLRD PSKAWSKRHL SYLRFPGDLF VQMLKMLILP  60
   61 MIMSSIITSL ASLDSGTAGR LGMVSMIYYT LTTFFAVFLG IVLVSVIKPG KWTTTNIEDL 120
  121 VGHVKTTPCV ATAVDTIIDL MKSCFPENLI EATFRSQKIC LKFFNGTTEI PPEIAMTMSP 180
  181 EQRAQFTEVP EKIVSDGMNI LGLVVFSVAL GIVIGVIGED GKPMKNFFKS LEACSMKLIG 240
  241 WVIIYSPVGI TFLIAAQIVG MKDPGQELHR LMGYVITVIL GLLIHAFVVI PLLCVVLARR 300
  301 NPIKFVGGMA QALLTALATS SSSATLPLSI KCCEENNKVD PRVTRFVLPL GATINMDGTA 360
  361 LYEAVAAIYI SQCYGNDLSL GEVVLVSLTA TLASIGAAGI PQAGIVTMIM VLIAIGLPTN 420
  421 LFILIFPVDF MLDRLRTTVN VHGDSIATAV IERLCEDQLQ KGGHHLDTND QGYSMLSTNA 480
  481 SPDPKRITIG NNCENSHML

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.30103
Match: 1xfhA
Description: Structure of glutamate transporter homolog from Pyrococcus horikoshii
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
high-affinity glutamate transmembrane transporter activity 9.03564241021137 bayes_pls_golite062009
dicarboxylic acid transmembrane transporter activity 8.28237742051097 bayes_pls_golite062009
L-aspartate transmembrane transporter activity 6.32804156021168 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 6.20769381184606 bayes_pls_golite062009
organic acid transmembrane transporter activity 6.19258658226115 bayes_pls_golite062009
transporter activity 5.14616859489508 bayes_pls_golite062009
substrate-specific transporter activity 5.08516306839475 bayes_pls_golite062009
transmembrane transporter activity 5.06400974103865 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.03536308870823 bayes_pls_golite062009
anion:cation symporter activity 4.98731042525142 bayes_pls_golite062009
ion transmembrane transporter activity 4.56245375639148 bayes_pls_golite062009
L-glutamate transmembrane transporter activity 4.55490142908046 bayes_pls_golite062009
acidic amino acid transmembrane transporter activity 4.55490142908046 bayes_pls_golite062009
cation transmembrane transporter activity 4.38524103588396 bayes_pls_golite062009
active transmembrane transporter activity 4.37939766329509 bayes_pls_golite062009
secondary active transmembrane transporter activity 3.93820513423101 bayes_pls_golite062009
amine transmembrane transporter activity 3.7335977004076 bayes_pls_golite062009
L-amino acid transmembrane transporter activity 3.55306444119183 bayes_pls_golite062009
solute:cation symporter activity 3.47181854698038 bayes_pls_golite062009
symporter activity 3.47181854698038 bayes_pls_golite062009
organic acid:sodium symporter activity 3.44677545809568 bayes_pls_golite062009
amino acid transmembrane transporter activity 3.22640982674356 bayes_pls_golite062009
solute:hydrogen symporter activity 3.11518167297447 bayes_pls_golite062009
C4-dicarboxylate transmembrane transporter activity 2.522484225611 bayes_pls_golite062009
L-cystine transmembrane transporter activity 2.23126735245762 bayes_pls_golite062009
anion transmembrane transporter activity 2.02127810434029 bayes_pls_golite062009
solute:sodium symporter activity 1.76557983021416 bayes_pls_golite062009
protein binding 1.39188421476117 bayes_pls_golite062009
binding 1.33552537079117 bayes_pls_golite062009
L-threonine transmembrane transporter activity 1.13816899539559 bayes_pls_golite062009
L-serine transmembrane transporter activity 1.13816899539559 bayes_pls_golite062009
L-proline transmembrane transporter activity 1.13816899539559 bayes_pls_golite062009
L-alanine transmembrane transporter activity 1.13816899539559 bayes_pls_golite062009
serine transmembrane transporter activity 1.13816899539559 bayes_pls_golite062009
L-hydroxyproline transmembrane transporter activity 1.13816899539559 bayes_pls_golite062009
alanine transmembrane transporter activity 1.13816899539559 bayes_pls_golite062009
amino acid binding 1.0487791191866 bayes_pls_golite062009
cation:amino acid symporter activity 0.85052491897986 bayes_pls_golite062009
sulfur amino acid transmembrane transporter activity 0.791452273778402 bayes_pls_golite062009
amine binding 0.621133377213499 bayes_pls_golite062009
glutamate:sodium symporter activity 0.553718735358201 bayes_pls_golite062009
neutral amino acid transmembrane transporter activity 0.444280550441749 bayes_pls_golite062009
monocarboxylic acid transmembrane transporter activity 0.31624582149961 bayes_pls_golite062009
neurotransmitter transporter activity 0.25304246415333 bayes_pls_golite062009
passive transmembrane transporter activity 0.119412711778045 bayes_pls_golite062009
channel activity 0.119412711778045 bayes_pls_golite062009
substrate-specific channel activity 0.0999184515491418 bayes_pls_golite062009

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