YRC Public Data Repository - Protein Structure Prediction

Protein:	RNPA_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	121 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNPA_COXBU.

Description	E-value	Query Range	Subject Range
RNPA_SODGM - Ribonuclease P protein component OS=Sodalis glossinidius (strain morsitans) GN=rnpA PE=3 SV=1	135.0	[0..4]	[117..5]
gi\|49077256 - gi\|49077256\|gb\|AAT49655.1\| PA5569 [synthetic construct]	132.0	[0..1]	[120..2]
RNPA_PECAS - Ribonuclease P protein component OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN... RNPA_ERWCT - Ribonuclease P protein component OS=Erwinia carotovora subsp. atroseptica GN=rnpA PE=3 SV=1	132.0	[0..4]	[116..5]
RNPA_YERE8 - Ribonuclease P protein component OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 1... gi\|77973773 - gi\|77973773\|ref\|ZP_00829318.1\| COG0594: RNase P protein component [Yersinia frederiksenii ATCC 33641...	131.0	[0..4]	[118..5]
RNPA_YERPA - Ribonuclease P protein component OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=rnpA PE=3 SV=1 RNPA_YERPN - Ribonuclease P protein component OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=rnpA PE=3 SV=1 RNPA_YERP3 - Ribonuclease P protein component OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=r... gi\|89101594 - gi\|89101594\|ref\|ZP_01174320.1\| COG0594: RNase P protein component [Yersinia pestis biovar Orientalis... RNPA_YERPS - Ribonuclease P protein component OS=Yersinia pseudotuberculosis GN=rnpA PE=3 SV=1 gi\|150260965, gi... - gi\|150260965\|ref\|ZP_01917693.1\| ribonuclease P protein [Yersinia pestis CA88-4125], gi\|149290373\|gb\|... gi\|229839807, gi... - gi\|229839807\|ref\|ZP_04459966.1\| protein C5 component of RNase P [Yersinia pestis biovar Orientalis s... RNPA_YERPE - Ribonuclease P protein component OS=Yersinia pestis GN=rnpA PE=3 SV=1 RNPA_YERPP - Ribonuclease P protein component OS=Yersinia pestis (strain Pestoides F) GN=rnpA PE=3 SV=1 gi\|229841892, gi... - gi\|229841892\|ref\|ZP_04462048.1\| protein C5 component of RNase P [Yersinia pestis biovar Orientalis s... gi\|229896769, gi... - gi\|229896769\|ref\|ZP_04511932.1\| protein C5 component of RNase P [Yersinia pestis Pestoides A], gi\|22... gi\|21961129, gi\|... - gi\|22127983\|ref\|NP_671406.1\| ribonuclease P [Yersinia pestis KIM], gi\|21961129\|gb\|AAM87657.1\|AE01401... RNPA_YERPS - Ribonuclease P protein component OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=rnpA ... gi\|45443731, gi\|... - gi\|45443731\|ref\|NP_995270.1\| ribonuclease P [Yersinia pestis biovar Microtus str. 91001], gi\|4543860... gi\|15981990, gi\|... - gi\|218931077\|ref\|YP_002348952.1\| ribonuclease P [Yersinia pestis CO92], gi\|16124209\|ref\|NP_407522.1\|...	131.0	[0..4]	[118..5]
RNPA_PHOLL - Ribonuclease P protein component OS=Photorhabdus luminescens subsp. laumondii GN=rnpA PE=3 SV=1 RNPA_PHOLL - Ribonuclease P protein component OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CI...	131.0	[0..4]	[118..5]
RNPA_PSEAE - Ribonuclease P protein component OS=Pseudomonas aeruginosa GN=rnpA PE=3 SV=1 RNPA_PSEAB - Ribonuclease P protein component OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=rnpA PE=3 SV=1 RNPA_PSEAE - Ribonuclease P protein component OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 ... gi\|126196491, gi... - gi\|84324747\|ref\|ZP_00972802.1\| COG0594: RNase P protein component [Pseudomonas aeruginosa 2192], gi\|... gi\|107104670 - gi\|107104670\|ref\|ZP_01368588.1\| hypothetical protein PaerPA_01005749 [Pseudomonas aeruginosa PACS2]	131.0	[0..1]	[120..2]
RNPA_PSEPF - Ribonuclease P protein component OS=Pseudomonas fluorescens (strain Pf0-1) GN=rnpA PE=3 SV=1	131.0	[0..1]	[119..1]
gi\|77958162 - gi\|77958162\|ref\|ZP_00822200.1\| COG0594: RNase P protein component [Yersinia bercovieri ATCC 43970]	130.0	[0..4]	[118..5]
gi\|227165130, gi... - gi\|227354812\|ref\|ZP_03839229.1\| ribonuclease P protein component [Proteus mirabilis ATCC 29906], gi\|... RNPA_PROMI - Ribonuclease P protein component OS=Proteus mirabilis GN=rnpA PE=3 SV=1 RNPA_PROMH - Ribonuclease P protein component OS=Proteus mirabilis (strain HI4320) GN=rnpA PE=3 SV=1	130.0	[0..4]	[118..5]

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Predicted Domain #1

Region A:
Residues: [1-121]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKGFSVGWR IRTTAEFRRI YAARQRIIGR YYLLYYRENE IKHSRLGVVA SKRNVRKAVW  60
   61 RNRVRRVVKE AFRIRKKDLP AFDIVVVAKA SSVEADNKEL YECINKLFTQ LEKQSKRSSS 120
  121 V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.39794
Match:	1a6fA
Description:	RNASE P PROTEIN FROM BACILLUS SUBTILIS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tRNA-specific ribonuclease activity	6.1454778021122	bayes_pls_golite062009
ribonuclease P activity	5.34408239201797	bayes_pls_golite062009
structural constituent of ribosome	3.49304472389303	bayes_pls_golite062009
RNA binding	2.94550290381601	bayes_pls_golite062009
structural molecule activity	2.91017901273919	bayes_pls_golite062009
3'-5'-exoribonuclease activity	2.16830676862423	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.94887328847363	bayes_pls_golite062009
exoribonuclease activity	1.90081280972069	bayes_pls_golite062009
mRNA binding	1.42024615739664	bayes_pls_golite062009
ribonuclease activity	1.31550811238109	bayes_pls_golite062009
transcription regulator activity	1.20748032530392	bayes_pls_golite062009
nucleic acid binding	1.05662964529454	bayes_pls_golite062009
binding	0.907487229190259	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
DNA binding	0.828609700556836	bayes_pls_golite062009
nuclease activity	0.69721312877891	bayes_pls_golite062009
3'-5' exonuclease activity	0.477960254167	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: