YRC Public Data Repository - Protein Structure Prediction

Protein:	ILVE_ECOLI
Organism:	Escherichia coli
Length:	309 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ILVE_ECOLI.

Description	E-value	Query Range	Subject Range
ILVE_SALTY - Branched-chain-amino-acid aminotransferase OS=Salmonella typhimurium GN=ilvE PE=1 SV=2 ILVE_SALTI - Branched-chain-amino-acid aminotransferase OS=Salmonella typhi GN=ilvE PE=3 SV=2 ILVE_SALTY - Branched-chain-amino-acid aminotransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7... gi\|213981032 - gi\|213981032\|ref\|ZP_03408291.1\| branched-chain amino acid aminotransferase [Salmonella enterica subs... gi\|213864754 - gi\|213864754\|ref\|ZP_03386873.1\| branched-chain amino acid aminotransferase [Salmonella enterica subs... ILVE_SALTI - Branched-chain-amino-acid aminotransferase OS=Salmonella typhi GN=ilvE PE=3 SV=2 gi\|213646697 - gi\|213646697\|ref\|ZP_03376750.1\| branched-chain amino acid aminotransferase [Salmonella enterica subs... gi\|29143717, gi\|... - gi\|29143717\|ref\|NP_807059.1\| branched-chain amino acid aminotransferase [Salmonella enterica subsp. ... gi\|16762228 - gi\|16762228\|ref\|NP_457845.1\| branched-chain amino acid aminotransferase [Salmonella enterica subsp. ... gi\|167553329, gi... - gi\|205322227\|gb\|EDZ10066.1\| branched-chain amino acid aminotransferase [Salmonella enterica subsp. e... ILVE_SALTY - Branched-chain-amino-acid aminotransferase OS=Salmonella typhimurium GN=ilvE PE=1 SV=2 gi\|161617020, gi... - gi\|161617020\|ref\|YP_001590985.1\| branched-chain amino acid aminotransferase [Salmonella enterica sub... lcl\|NC_016856.1_... - [gene=ilvE] [protein=branched-chain amino acid aminotransferase] [protein_id=YP_005240165.1] [locati... gi\|213425638 - gi\|213425638\|ref\|ZP_03358388.1\| branched-chain amino acid aminotransferase [Salmonella enterica subs... gi\|194713775, gi... - gi\|194738273\|ref\|YP_002116837.1\| branched-chain amino acid aminotransferase [Salmonella enterica sub... gi\|168238357, gi... - gi\|197288739\|gb\|EDY28114.1\| branched-chain amino acid aminotransferase [Salmonella enterica subsp. e... gi\|167994598, gi... - gi\|205327552\|gb\|EDZ14316.1\| branched-chain amino acid aminotransferase [Salmonella enterica subsp. e...	369.0	[0..1]	[308..1]
gi\|353522 - gi\|353522\|prf\|\|1104250A aminotransferase,branched chain AA	368.0	[0..1]	[309..7]
gi\|30064933, gi\|... - gi\|30064933\|ref\|NP_839104.1\| branched-chain amino acid aminotransferase [Shigella flexneri 2a str. 2... gi\|229774929 - gi\|229774929\|ref\|YP_691058.2\| branched-chain amino acid aminotransferase [Shigella flexneri 5 str. 8... gi\|24115065, gi\|... - gi\|24115065\|ref\|NP_709575.1\| branched-chain amino acid aminotransferase [Shigella flexneri 2a str. 3...	368.0	[0..1]	[309..1]
gi\|110644100, gi... - gi\|110644100\|ref\|YP_671830.1\| branched-chain amino acid aminotransferase [Escherichia coli 536], gi\|... gi\|75236526, gi\|... - gi\|75236526\|ref\|ZP_00720616.1\| COG0115: Branched-chain amino acid aminotransferase/4-amino-4-deoxych... gi\|91213292, gi\|... - gi\|91213292\|ref\|YP_543278.1\| branched-chain amino acid aminotransferase [Escherichia coli UTI89], gi... gi\|117626033, gi... - gi\|117626033\|ref\|YP_859356.1\| branched-chain amino acid aminotransferase [Escherichia coli APEC O1],... gi\|237702781, gi... - gi\|237702781\|ref\|ZP_04533262.1\| branched-chain amino acid aminotransferase [Escherichia sp. 3_2_53FA... gi\|218692050, gi... - gi\|218692050\|ref\|YP_002400262.1\| branched-chain amino acid aminotransferase [Escherichia coli ED1a],... gi\|218367606, gi... - gi\|218560837\|ref\|YP_002393750.1\| branched-chain amino acid aminotransferase [Escherichia coli S88], ...	368.0	[0..1]	[309..1]
gi\|75209007, gi\|... - gi\|75209007\|ref\|ZP_00709271.1\| COG0115: Branched-chain amino acid aminotransferase/4-amino-4-deoxych... gi\|194438594, gi... - gi\|83585975\|ref\|ZP_00924614.1\| COG0115: Branched-chain amino acid aminotransferase/4-amino-4-deoxych... gi\|254290465, gi... - gi\|254290465\|ref\|YP_003056213.1\| branched-chain amino acid aminotransferase [Escherichia coli BL21(D... gi\|242379303, gi... - gi\|251787030\|ref\|YP_003001334.1\| hypothetical protein B21_03597 [Escherichia coli BL21], gi\|24237930... gi\|254163715, gi... - gi\|254163715\|ref\|YP_003046823.1\| branched-chain amino acid aminotransferase [Escherichia coli B str.... gi\|75255777, gi\|... - gi\|75255777\|ref\|ZP_00727531.1\| COG0115: Branched-chain amino acid aminotransferase/4-amino-4-deoxych... gi\|190903852, gi... - gi\|75230738\|ref\|ZP_00717201.1\| COG0115: Branched-chain amino acid aminotransferase/4-amino-4-deoxych...	367.0	[0..1]	[309..1]
gi\|56415762, gi\|... - gi\|56415762\|ref\|YP_152837.1\| branched-chain amino acid aminotransferase [Salmonella enterica subsp. ... gi\|197364691, gi... - gi\|197364691\|ref\|YP_002144328.1\| branched-chain amino acid aminotransferase [Salmonella enterica sub...	367.0	[0..1]	[307..1]
gi\|224470253, gi... - gi\|224585725\|ref\|YP_002639524.1\| branched-chain amino acid aminotransferase [Salmonella enterica sub... gi\|238912911 - gi\|238912911\|ref\|ZP_04656748.1\| branched-chain amino acid aminotransferase [Salmonella enterica subs... gi\|62182378, gi\|... - gi\|62182378\|ref\|YP_218795.1\| branched-chain amino acid aminotransferase [Salmonella enterica subsp. ...	366.0	[0..1]	[308..1]
gi\|74314284, gi\|... - gi\|74314284\|ref\|YP_312703.1\| branched-chain amino acid aminotransferase [Shigella sonnei Ss046], gi\|...	365.0	[0..1]	[309..1]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTKKADYIW FNGEMVRWED AKVHVMSHAL HYGTSVFEGI RCYDSHKGPV VFRHREHMQR  60
   61 LHDSAKIYRF PVSQSIDELM EACRDVIRKN NLTSAYIRPL IFVGDVGMGV NPPAGYSTDV 120
  121 IIAAFPWGAY LGAEALEQGI DAMVSSWNRA APNTIPTAAK AGGNYLSSLL VGSEARRHGY 180
  181 QEGIALDVNG YISEGAGENL FEVKDGVLFT PPFTSSALPG ITRDAIIKLA KELGIEVREQ 240
  241 VLSRESLYLA DEVFMSGTAA EITPVRSVDG IQVGEGRCGP VTKRIQQAFF GLFTGETEDK 300
  301 WGWLDQVNQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	102.0
Match:	1i1kA
Description:	Branched-chain aminoacid aminotransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
branched-chain-amino-acid transaminase activity	5.31468228742342	bayes_pls_golite062009
L-alanine:2-oxoglutarate aminotransferase activity	2.72280299326621	bayes_pls_golite062009
alanine-oxo-acid transaminase activity	2.72280299326621	bayes_pls_golite062009
catalytic activity	2.42233634542616	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	2.24372201513675	bayes_pls_golite062009
transaminase activity	2.22194941712055	bayes_pls_golite062009
transferase activity	1.87055521105017	bayes_pls_golite062009
binding	1.1152974834671	bayes_pls_golite062009
pyridoxal phosphate binding	0.92252822492163	bayes_pls_golite062009
vitamin B6 binding	0.92252822492163	bayes_pls_golite062009
D-alanine:2-oxoglutarate aminotransferase activity	0.1743062521428	bayes_pls_golite062009
protein binding	0.120924367164485	bayes_pls_golite062009
cofactor binding	0.0813158351261423	bayes_pls_golite062009
vitamin binding	0.0806513488943901	bayes_pls_golite062009
steroid binding	0.026124581502876	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: