YRC Public Data Repository - Protein Structure Prediction

Protein:	FENR_ECOLI
Organism:	Escherichia coli
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FENR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|56459320, gi\|... - gi\|56459320\|ref\|YP_154601.1\| ferredoxin-NADP reductase [Idiomarina loihiensis L2TR], gi\|56178330\|gb\|...	224.0	[0..1]	[248..1]
gi\|85695284, gi\|... - gi\|85710880\|ref\|ZP_01041941.1\| Ferredoxin-NADP reductase [Idiomarina baltica OS145], gi\|85695284\|gb\|...	221.0	[0..1]	[248..1]
gi\|49613715, gi\|... - gi\|50123189\|ref\|YP_052356.1\| ferredoxin-NADP reductase [Pectobacterium atrosepticum SCRI1043], gi\|49...	220.0	[0..1]	[248..1]
gi\|238798302, gi... - gi\|77961047\|ref\|ZP_00824895.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1...	220.0	[0..1]	[248..1]
gi\|238789588, gi... - gi\|77972970\|ref\|ZP_00828524.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1...	220.0	[0..1]	[248..1]
gi\|56314731, gi\|... - gi\|56478688\|ref\|YP_160277.1\| hypothetical protein ebA5725 [Aromatoleum aromaticum EbN1], gi\|56314731...	218.0	[0..1]	[240..1]
gi\|238712991, gi... - gi\|77957397\|ref\|ZP_00821454.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1...	217.0	[0..1]	[248..1]
gi\|77977388, gi\|... - gi\|77977388\|ref\|ZP_00832838.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1...	215.0	[0..1]	[248..1]
gi\|157831052, gi... - gi\|2554661\|pdb\|1FDR\| Chain , Flavodoxin Reductase From E. Coli, gi\|157831052\|pdb\|1FDR\|A Chain A, F...	215.0	[0..1]	[248..1]
FENR_SHIFL - Ferredoxin--NADP reductase OS=Shigella flexneri GN=fpr PE=3 SV=3 gi\|218363255, gi... - gi\|218556486\|ref\|YP_002389400.1\| ferredoxin-NADP reductase [Escherichia coli IAI1], gi\|218363255\|emb... gi\|209914663, gi... - gi\|209921404\|ref\|YP_002295488.1\| ferredoxin-NADP reductase [Escherichia coli SE11], gi\|209914663\|dbj... gi\|218354370, gi... - gi\|218697638\|ref\|YP_002405305.1\| ferredoxin-NADP reductase [Escherichia coli 55989], gi\|218354370\|em... gi\|82546273, gi\|... - gi\|82546273\|ref\|YP_410220.1\| ferredoxin-NADP reductase [Shigella boydii Sb227], gi\|81247684\|gb\|ABB68... gi\|110617333, gi... - gi\|110807785\|ref\|YP_691305.1\| ferredoxin-NADP reductase [Shigella flexneri 5 str. 8401], gi\|11061733... gi\|75211262, gi\|... - gi\|75211262\|ref\|ZP_00711361.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1... gi\|75188659, gi\|... - gi\|75188659\|ref\|ZP_00701926.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1... gi\|187427344, gi... - gi\|75176689\|ref\|ZP_00696817.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1... gi\|30064783, gi\|... - gi\|30064783\|ref\|NP_838954.1\| ferredoxin-NADP reductase [Shigella flexneri 2a str. 2457T], gi\|3004304... gi\|81243055, gi\|... - gi\|82778907\|ref\|YP_405256.1\| ferredoxin-NADP reductase [Shigella dysenteriae Sd197], gi\|81243055\|gb\|... gi\|75258093, gi\|... - gi\|75258093\|ref\|ZP_00729554.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1... gi\|75238367, gi\|... - gi\|75238367\|ref\|ZP_00722366.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1... gi\|191166424, gi... - gi\|75230445\|ref\|ZP_00716931.1\| COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1... gi\|24115218, gi\|... - gi\|24115218\|ref\|NP_709728.1\| ferredoxin-NADP reductase [Shigella flexneri 2a str. 301], gi\|24054503\|...	215.0	[0..1]	[248..1]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADWVTGKVT KVQNWTDALF SLTVHAPVLP FTAGQFTKLG LEIDGERVQR AYSYVNSPDN  60
   61 PDLEFYLVTV PDGKLSPRLA ALKPGDEVQV VSEAAGFFVL DEVPHCETLW MLATGTAIGP 120
  121 YLSILQLGKD LDRFKNLVLV HAARYAADLS YLPLMQELEK RYEGKLRIQT VVSRETAAGS 180
  181 LTGRIPALIE SGELESTIGL PMNKETSHVM LCGNPQMVRD TQQLLKETRQ MTKHLRRRPG 240
  241 HMTAEHYW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.09691
Match:	1fdrA
Description:	FLAVODOXIN REDUCTASE FROM E. COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.45374095556065	bayes_pls_golite062009
binding	0.450899702470978	bayes_pls_golite062009
coenzyme binding	0.270924422726986	bayes_pls_golite062009
cofactor binding	0.2333379637469	bayes_pls_golite062009
transferase activity	0.00498326987177106	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: