YRC Public Data Repository - Protein Structure Prediction

Protein:	FABI_ECOLI
Organism:	Escherichia coli
Length:	262 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABI_ECOLI.

Description	E-value	Query Range	Subject Range
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	270.0	[0..3]	[253..2]
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	269.0	[0..1]	[253..1]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	267.0	[0..1]	[253..1]
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	267.0	[0..1]	[253..1]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	264.0	[0..4]	[253..2]
gi\|89098688, gi\|... - gi\|89098688\|ref\|ZP_01171570.1\| beta-ketoacyl-acyl carrier protein reductase [Bacillus sp. NRRL B-149...	263.0	[0..3]	[253..2]
gi\|168210762, gi... - gi\|170711222\|gb\|EDT23404.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens B st... gi\|110675446, gi... - gi\|110800799\|ref\|YP_695772.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens A... gi\|170660709, gi... - gi\|170660709\|gb\|EDT13392.1\| 3-oxoacyl- reductase [Clostridium perfringens E str. JGS1987], gi\|168207...	260.0	[0..4]	[253..2]
gi\|91184216, gi\|... - gi\|91217712\|ref\|ZP_01254669.1\| putative 3-oxoacyl-[acyl-carrier protein] reductase [Psychroflexus to...	260.0	[0..1]	[252..8]
gi\|110803752, gi... - gi\|110803752\|ref\|YP_698460.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens S...	260.0	[0..4]	[253..2]
gi\|219540094, gi... - gi\|68206640\|ref\|ZP_00558823.1\| Glucose/ribitol dehydrogenase [Desulfitobacterium hafniense DCB-2], g...	259.0	[0..4]	[253..3]

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Predicted Domain #1

Region A:
Residues: [1-262]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFLSGKRIL VTGVASKLSI AYGIAQAMHR EGAELAFTYQ NDKLKGRVEE FAAQLGSDIV  60
   61 LQCDVAEDAS IDTMFAELGK VWPKFDGFVH SIGFAPGDQL DGDYVNAVTR EGFKIAHDIS 120
  121 SYSFVAMAKA CRSMLNPGSA LLTLSYLGAE RAIPNYNVMG LAKASLEANV RYMANAMGPE 180
  181 GVRVNAISAG PIRTLAASGI KDFRKMLAHC EAVTPIRRTV TIEDVGNSAA FLCSDLSAGI 240
  241 SGEVVHVDGG FSIAAMNELE LK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.39794
Match:	1qsgA
Description:	Enoyl-ACP reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
steroid dehydrogenase activity	1.75109362865449	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.55012034958204	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	1.29098300860169	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
retinol dehydrogenase activity	1.16811519855038	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.977681939875779	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	0.65743456407889	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
binding	0.405786564527334	bayes_pls_golite062009
enoyl-CoA hydratase activity	0.15639913603713	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.0385886223537015	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: