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View Structure Prediction Details

Protein: gi|7494353
Organism: Plasmodium falciparum
Length: 679 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7494353.

Description E-value Query
Range
Subject
Range
gi|23490791 - gi|23490791|gb|EAA22480.1| Patatin, putative [Plasmodium yoelii yoelii]
gi|83315723 - gi|83315723|ref|XP_730915.1| patatin [Plasmodium yoelii yoelii str. 17XNL]
533.0 [0..1] [678..1]
gi|68070595 - gi|68070595|ref|XP_677209.1| phospholipase [Plasmodium berghei strain ANKA]
gi|56497234 - gi|56497234|emb|CAH95770.1| phospholipase, putative [Plasmodium berghei]
523.0 [0..1] [678..1]
gi|56517904 - gi|56517904|emb|CAH79227.1| phospholipase, putative [Plasmodium chabaudi chabaudi]
gi|70939513 - gi|70939513|ref|XP_740288.1| phospholipase [Plasmodium chabaudi chabaudi]
299.0 [0..127] [605..1]
gi|125603755, gi... - gi|50946833|ref|XP_482944.1| putative latex protein allergen [Oryza sativa (japonica cultivar-group)...
279.0 [0..282] [676..2]
gi|4539677, gi|2... - gi|4539677|gb|AAD22170.1|AF061282_24 patatin-like protein [Sorghum bicolor], gi|242071683|ref|XP_002...
272.0 [0..321] [677..11]
gi|2632059, gi|2... - gi|2632059|emb|CAA05628.1| patatin-like protein [Arabidopsis thaliana], pir||T52294 patatin-like pro...
263.0 [0..325] [677..5]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDDDDKIYI YSDLFSKNFS DDEKDDSYER EKQVYSGSET QNAENEYSKL RAQNSTILNN  60
   61 YFDNDNIKNV ENLKSNDPDQ IDLILFPVNK NYYMNLFDGQ LIENIHSIKL RKAGFYAIYV 120
  121 ENNNNSKWDG IYFGLSRMQV ELDYKLITKK NKDGGEYEKR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTSSYDNTES VQNTVGSEKE ETENKNEETS NYNSNLNNEI NKICKYNLDQ TDILLDDSNS  60
   61 ERRRNSKFKI KNTNYYDNLM LQNKYTNSIL YDDDDDKNNT ETYTCTFKTE DQIRVPSQKK 120
  121 KYIYLYNKYD NATLDLNVHT YMSLGMSILC KYSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [315-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYCGKYNHIP RDPYTPFKKP VSILSLDGGG ILTISTLLVL NRLEAELRKE IGSDDIKLID  60
   61 CFDMVCGTSA GGLISLALLR EIDLQDVSNM WPSTIKKVFE GNRNIISGIF FEGYDVNNVK 120
  121 DVFLERMGNK FMSSYKKFYC FVTATDVKHK PYKLFLIRNY THKYNSINAE SYDGINKVPL 180
  181 WLAAWATASA PTYLKGPSAE DIKKLGINIK PEIHLVDGAL KASNPALIAL EECARLNNKN 240
  241 LSTFIKEDLD TLVSIGTGQV PTKLTQSGAS SKSASTFEIL INSTHLLTRA NDTHREVLQR 300
  301 LADRENTYFR FNVPHIGDIE IDSQDVRDFD LISKATQDYL FDEKFYEIKR LAHKLANNYI 360
  361 RSKYL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.69897
Match: 1oxwA
Description: Patatin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipase A2 activity 1.89031439432148 bayes_pls_golite062009
phospholipase activity 1.80454369034948 bayes_pls_golite062009
catalytic activity 1.681309422157 bayes_pls_golite062009
lipase activity 1.58686349518315 bayes_pls_golite062009
carboxylesterase activity 0.543259402611534 bayes_pls_golite062009
fatty acid synthase activity 0.329404484316401 bayes_pls_golite062009
[acyl-carrier-protein] S-malonyltransferase activity 0.0338319024433758 bayes_pls_golite062009
S-malonyltransferase activity 0.0338319024433758 bayes_pls_golite062009
malonyltransferase activity 0.0338319024433758 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle