YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1773103, gi\|7...
Organism:	Escherichia coli
Length:	348 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1773103, gi|7....

Description	E-value	Query Range	Subject Range
gi\|33596263 - gi\|33596263\|ref\|NP_883906.1\| putative oxidoreductase [Bordetella parapertussis 12822] gi\|33573266 - gi\|33573266\|emb\|CAE36928.1\| putative oxidoreductase [Bordetella parapertussis]	371.0	[0..25]	[347..1]
gi\|33602077, gi\|... - gi\|33602077\|ref\|NP_889637.1\| putative oxidoreductase [Bordetella bronchiseptica RB50], gi\|33576515\|e...	370.0	[0..25]	[347..1]
gi\|33592063, gi\|... - gi\|33592063\|ref\|NP_879707.1\| putative oxidoreductase [Bordetella pertussis Tohama I], gi\|33571707\|em...	369.0	[0..25]	[347..1]
gi\|115511804, gi... - gi\|117622680\|ref\|YP_851593.1\| oxidoreductase, NAD(P)-binding [Escherichia coli APEC O1], gi\|11551180... gi\|218557328, gi... - gi\|218557328\|ref\|YP_002390241.1\| aldoketo-oxidoreductase, NADP-binding [Escherichia coli S88], gi\|21... gi\|91071062, gi\|... - gi\|91209488\|ref\|YP_539474.1\| oxidoreductase YajO [Escherichia coli UTI89], gi\|91071062\|gb\|ABE05943.1... gi\|237707587, gi... - gi\|237707587\|ref\|ZP_04538068.1\| oxidoreductase YajO [Escherichia sp. 3_2_53FAA], gi\|226898797\|gb\|EEH...	367.0	[0..25]	[348..1]
gi\|217325966, gi... - gi\|217325966\|ref\|ZP_03442050.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7... gi\|208731522, gi... - gi\|208814874\|ref\|ZP_03256053.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7... gi\|254591003, gi... - gi\|254791603\|ref\|YP_003076440.1\| predicted oxidoreductase, NAD(P)-binding [Escherichia coli O157:H7 ... gi\|208726543, gi... - gi\|208806742\|ref\|ZP_03249079.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7... gi\|209160502, gi... - gi\|209399102\|ref\|YP_002269064.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H... gi\|208822866, gi... - gi\|208822866\|ref\|ZP_03263184.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7... gi\|189373561, gi... - gi\|189373561\|gb\|EDU91977.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|168783284, gi... - gi\|188999385\|gb\|EDU68371.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|195938514 - gi\|195938514\|ref\|ZP_03083896.1\| putative NAD(P)H-dependent xylose reductase [Escherichia coli O157:H... gi\|189377410, gi... - gi\|189377410\|gb\|EDU95826.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|168761624, gi... - gi\|189368051\|gb\|EDU86467.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|168756960, gi... - gi\|189355987\|gb\|EDU74406.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|187768313, gi... - gi\|187768313\|gb\|EDU32157.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|168768369, gi... - gi\|189362458\|gb\|EDU80877.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|188015908, gi... - gi\|188015908\|gb\|EDU54030.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str... gi\|13359930, gi\|... - gi\|15829727\|ref\|NP_308500.1\| putative NAD(P)H-dependent xylose reductase [Escherichia coli O157:H7 s... gi\|25316196, gi\|... - pir\|\|E85538 probable NAD(P)H-dependent xylose reductase yajO [imported] - Escherichia coli (strain O... gi\|12513275, gi\|... - gi\|15800149\|ref\|NP_286161.1\| putative NAD(P)H-dependent xylose reductase [Escherichia coli O157:H7 E... gi\|13359930, gi\|... - gi\|15829727\|ref\|NP_308500.1\| putative NAD(P)H-dependent xylose reductase [Escherichia coli O157:H7],...	366.0	[0..25]	[348..1]
gi\|78062171, gi\|... - gi\|78062171\|ref\|YP_372079.1\| aldo/keto reductase [Burkholderia sp. 383], gi\|77970056\|gb\|ABB11435.1\| ...	366.0	[0..25]	[346..1]
gi\|91779252, gi\|... - gi\|91779252\|ref\|YP_554460.1\| putative aldo/keto reductase [Burkholderia xenovorans LB400], gi\|916919...	366.0	[0..25]	[347..1]
gi\|169887840, gi... - gi\|170080005\|ref\|YP_001729325.1\| oxidoreductase, NAD(P)-binding [Escherichia coli str. K-12 substr. ... gi\|170021209, gi... - gi\|170021209\|ref\|YP_001726163.1\| aldo/keto reductase [Escherichia coli ATCC 8739], gi\|169756137\|gb\|A... gi\|85674559, gi\|... - gi\|89107289\|ref\|AP_001069.1\| predicted oxidoreductase, NAD(P)-binding [Escherichia coli str. K-12 su... EG13611 - 2-carboxybenzaldehyde reductase / 2-carboxybenzaldehyde reductase gi\|124500207, gi... - gi\|124528870\|ref\|ZP_01700055.1\| aldo/keto reductase [Escherichia coli B], gi\|124500207\|gb\|EAY47683.1... gi\|238859764, gi... - gi\|238899707\|ref\|YP_002925503.1\| 2-carboxybenzaldehyde reductase [Escherichia coli BW2952], gi\|23885... gi\|188486971, gi... - gi\|188491772\|ref\|ZP_02999042.1\| oxidoreductase, aldo/keto reductase family [Escherichia coli 53638],... EG13611 - 2-carboxybenzaldehyde reductase / 2-carboxybenzaldehyde reductase YAJO_ECOLI - Hypothetical oxidoreductase yajO (EC 1.-.-.-) - Escherichia coli	366.0	[0..25]	[348..1]
gi\|237797143, gi... - gi\|237797143\|ref\|YP_002887433.1\| putative oxidoreductase [Pseudomonas fluorescens], gi\|229424280\|gb\|... gi\|38638513, gi\|... - gi\|38638513\|ref\|NP_943099.1\| oxido-reductase/dehydratase [Pseudomonas sp. ND6], gi\|34335301\|gb\|AAP44... gi\|114050463 - gi\|114050463\|dbj\|BAF30949.1\| putative oxidoreductase [uncultured bacterium] gi\|28976073, gi\|... - gi\|32469911\|ref\|NP_863085.1\| putative oxidoreductase [Pseudomonas putida], gi\|28976073\|gb\|AAO64287.1...	365.0	[0..25]	[347..1]
gi\|26246425, gi\|... - gi\|26246425\|ref\|NP_752464.1\| oxidoreductase yajO [Escherichia coli CFT073], gi\|26106823\|gb\|AAN79008....	365.0	[0..25]	[348..1]

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Predicted Domain #1

Region A:
Residues: [1-348]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGVNECSRS TCNLKYDEYS RSGSMQYNPL GKTDLRVSRL CLGCMTFGEP DRGNHAWTLP  60
   61 EESSRPIIKR ALEGGINFFD TANSYSDGSS EEIVGRALRD FARREDVVVA TKVFHRVGDL 120
  121 PEGLSRAQIL RSIDDSLRRL GMDYVDILQI HRWDYNTPIE ETLEALNDVV KAGKARYIGA 180
  181 SSMHASQFAQ ALELQKQHGW AQFVSMQDHY NLIYREEERE MLPLCYQEGV AVIPWSPLAR 240
  241 GRLTRPWGET TARLVSDEVG KNLYKESDEN DAQIAERLTG VSEELGATRA QVALAWLLSK 300
  301 PGIAAPIIGT SREEQLDELL NAVDITLKPE QIAELETPYK PHPVVGFK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.09691
Match:	1exbA
Description:	Voltage-dependent K+ channel beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	7.51963276589303	bayes_pls_golite062009
voltage-gated potassium channel activity	7.40239094355354	bayes_pls_golite062009
voltage-gated cation channel activity	6.67507110634301	bayes_pls_golite062009
metal ion transmembrane transporter activity	6.588881463055	bayes_pls_golite062009
voltage-gated ion channel activity	6.52286930358188	bayes_pls_golite062009
voltage-gated channel activity	6.50716590143831	bayes_pls_golite062009
cation channel activity	5.72172645555113	bayes_pls_golite062009
ion channel activity	5.15119282480682	bayes_pls_golite062009
passive transmembrane transporter activity	5.07214658557001	bayes_pls_golite062009
channel activity	5.07214658557001	bayes_pls_golite062009
substrate-specific channel activity	5.02503292701043	bayes_pls_golite062009
gated channel activity	4.92848832197692	bayes_pls_golite062009
pyridoxine 4-dehydrogenase activity	3.25535446462297	bayes_pls_golite062009
ion transmembrane transporter activity	2.63772951680109	bayes_pls_golite062009
cation transmembrane transporter activity	2.58068601897668	bayes_pls_golite062009
aldo-keto reductase activity	2.57303336304449	bayes_pls_golite062009
aryl-alcohol dehydrogenase activity	2.5168190536972	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.46488926936937	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.48881830724998	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47641884930911	bayes_pls_golite062009
transporter activity	1.24767072239634	bayes_pls_golite062009
oxidoreductase activity	1.17915737521094	bayes_pls_golite062009
aldehyde reductase activity	1.16639404121425	bayes_pls_golite062009
binding	1.15657176144267	bayes_pls_golite062009
transmembrane transporter activity	1.03420335553507	bayes_pls_golite062009
potassium channel regulator activity	1.03017249802223	bayes_pls_golite062009
substrate-specific transporter activity	0.783004917746429	bayes_pls_golite062009
protein binding	0.220529867719707	bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity	0.207008954325429	bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	0.207008954325429	bayes_pls_golite062009
	0.139676323362391	bayes_pls_golite062009
channel regulator activity	0.12154513851913	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: