YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7471099
Organism:	Deinococcus radiodurans
Length:	327 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7471099.

Description	E-value	Query Range	Subject Range
gi\|66780950, gi\|... - gi\|94986270\|ref\|YP_605634.1\| aldo/keto reductase [Deinococcus geothermalis DSM 11300], gi\|94556551\|g...	3.0E-97	[4..327]	[1..324]
gi\|186684841, gi... - gi\|23125522\|ref\|ZP_00107451.1\| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydroge...	6.0E-96	[4..327]	[1..326]
gi\|115365408, gi... - gi\|115377607\|ref\|ZP_01464804.1\| aldo/keto reductase [Stigmatella aurantiaca DW4/3-1], gi\|115365408\|g...	7.0E-96	[4..327]	[1..329]
gi\|50119681, gi\|... - gi\|50119681\|ref\|YP_048848.1\| putative aldo/keto reductase [Pectobacterium atrosepticum SCRI1043], gi...	4.0E-94	[4..319]	[1..320]
gi\|53761677, gi\|... - gi\|73543064\|ref\|YP_297584.1\| aldo/keto reductase [Ralstonia eutropha JMP134], gi\|72120477\|gb\|AAZ6274...	6.0E-94	[2..327]	[9..340]
gi\|85775968, gi\|... - gi\|86159457\|ref\|YP_466242.1\| aldo/keto reductase [Anaeromyxobacter dehalogenans 2CP-C], gi\|85775968\|...	9.0E-94	[4..325]	[1..324]
gi\|37520407, gi\|... - gi\|37520407\|ref\|NP_923784.1\| oxidoreductase [Gloeobacter violaceus PCC 7421], gi\|35211400\|dbj\|BAC887...	2.0E-93	[4..327]	[1..326]
gi\|126194344, gi... - gi\|254240966\|ref\|ZP_04934288.1\| hypothetical protein PA2G_01646 [Pseudomonas aeruginosa 2192], gi\|19... gi\|11351605 - pir\|\|H83328 probable oxidoreductase PA2535 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|218771712, gi... - gi\|218891486\|ref\|YP_002440353.1\| putative oxidoreductase [Pseudomonas aeruginosa LESB58], gi\|2187717... gi\|15597731, gi\|... - gi\|9948592\|gb\|AAG05923.1\|AE004681_5 probable oxidoreductase [Pseudomonas aeruginosa PAO1], gi\|155977...	8.0E-93	[4..321]	[1..323]
gi\|83756441, gi\|... - gi\|83815047\|ref\|YP_446502.1\| aldo/keto reductase [Salinibacter ruber DSM 13855], gi\|83756441\|gb\|ABC4...	9.0E-93	[3..327]	[67..393]
gi\|116050479, gi... - gi\|32037528\|ref\|ZP_00135800.1\| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydroge...	1.0E-92	[4..321]	[1..323]

Back

Predicted Domain #1

Region A:
Residues: [1-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTLPTRQLR DLTVSALGLG CMGMSEFYGD ADEAESLRTL DRALDLGVTF FDTADIYGPY  60
   61 HNEELLGRWL RGKRDRVVLA TKFGIVRDPA DPSRRGFSGR PEYVRQSIEG SLNRLGTDHV 120
  121 DLYYLHRVDP DTPIEDTVGA MADLVQEGKV RALGLSECSA DTLRRAHAVH PISAVQSEYS 180
  181 LWTRDPEENG VLAACRELGV GFVPYSPLGR GFLAGQLKSP DDLAPDDFRR HNPRFQDENF 240
  241 QKNLDLVREI ERLAAEKGCT PSQLALAWVL AQGENLVPIP GTKRVKYLEE NVGALDVRLT 300
  301 PDELRQIDAT FPVAAGDRYP DMRHVNR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.0
Match:	1pyfA
Description:	Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	7.51963276589303	bayes_pls_golite062009
voltage-gated potassium channel activity	7.40239094355354	bayes_pls_golite062009
voltage-gated cation channel activity	6.67507110634301	bayes_pls_golite062009
metal ion transmembrane transporter activity	6.588881463055	bayes_pls_golite062009
voltage-gated ion channel activity	6.52286930358188	bayes_pls_golite062009
voltage-gated channel activity	6.50716590143831	bayes_pls_golite062009
cation channel activity	5.72172645555113	bayes_pls_golite062009
ion channel activity	5.15119282480682	bayes_pls_golite062009
passive transmembrane transporter activity	5.07214658557001	bayes_pls_golite062009
channel activity	5.07214658557001	bayes_pls_golite062009
substrate-specific channel activity	5.02503292701043	bayes_pls_golite062009
gated channel activity	4.92848832197692	bayes_pls_golite062009
pyridoxine 4-dehydrogenase activity	3.25535446462297	bayes_pls_golite062009
ion transmembrane transporter activity	2.63772951680109	bayes_pls_golite062009
cation transmembrane transporter activity	2.58068601897668	bayes_pls_golite062009
aldo-keto reductase activity	2.57303336304449	bayes_pls_golite062009
aryl-alcohol dehydrogenase activity	2.5168190536972	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.46488926936937	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.48881830724998	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47641884930911	bayes_pls_golite062009
transporter activity	1.24767072239634	bayes_pls_golite062009
oxidoreductase activity	1.17915737521094	bayes_pls_golite062009
aldehyde reductase activity	1.16639404121425	bayes_pls_golite062009
binding	1.15657176144267	bayes_pls_golite062009
transmembrane transporter activity	1.03420335553507	bayes_pls_golite062009
potassium channel regulator activity	1.03017249802223	bayes_pls_golite062009
substrate-specific transporter activity	0.783004917746429	bayes_pls_golite062009
protein binding	0.220529867719707	bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity	0.207008954325429	bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	0.207008954325429	bayes_pls_golite062009
	0.139676323362391	bayes_pls_golite062009
channel regulator activity	0.12154513851913	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: