YRC Public Data Repository - Protein Structure Prediction

Protein:	AHPF_PSEAE
Organism:	Pseudomonas aeruginosa PAO1
Length:	521 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AHPF_PSEAE.

Description	E-value	Query Range	Subject Range
gi\|116053860, gi... - gi\|116053860\|ref\|YP_788297.1\| alkyl hydroperoxide reductase subunit F [Pseudomonas aeruginosa UCBPP-...	0.0	[1..521]	[1..521]
gi\|68345057, gi\|... - gi\|70730758\|ref\|YP_260499.1\| alkyl hydroperoxide reductase, subunit F [Pseudomonas fluorescens Pf-5]...	0.0	[1..520]	[1..520]
gi\|77459149, gi\|... - gi\|77459149\|ref\|YP_348655.1\| pyridine nucleotide-disulphide oxidoreductase class-II [Pseudomonas flu...	0.0	[1..520]	[1..519]
AHPF_PSEPU - Alkyl hydroperoxide reductase subunit F OS=Pseudomonas putida GN=ahpF PE=3 SV=1 AHPF_PSEPK - Alkyl hydroperoxide reductase subunit F OS=Pseudomonas putida (strain KT2440) GN=ahpF PE=3 SV=1	0.0	[1..520]	[1..519]
gi\|82717667, gi\|... - gi\|82734992\|ref\|ZP_00897855.1\| alkyl hydroperoxide reductase, F subunit [Pseudomonas putida F1], gi\|...	0.0	[1..520]	[1..519]
gi\|48764781 - ref\|ZP_00269332.1\| COG3634: Alkyl hydroperoxide reductase, large subunit [Rhodospirillum rubrum] gi\|83575667, gi\|... - gi\|83592753\|ref\|YP_426505.1\| thioredoxin-disulfide reductase [Rhodospirillum rubrum ATCC 11170], gi\|...	0.0	[1..521]	[1..521]
gi\|68266229 - gi\|68266229\|gb\|AAY88878.1\| AhpF [Azospirillum brasilense]	0.0	[1..521]	[1..522]
gi\|28870280, gi\|... - gi\|28870280\|ref\|NP_792899.1\| alkyl hydroperoxide reductase, subunit F [Pseudomonas syringae pv. toma... tr\|Q880P7\|Q880P7... - Alkyl hydroperoxide reductase, subunit F OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=ahpF ... gi\|213970401, gi... - gi\|213970401\|ref\|ZP_03398530.1\| alkyl hydroperoxide reductase, subunit F [Pseudomonas syringae pv. t...	0.0	[1..520]	[1..519]
gi\|71733341, gi\|... - gi\|71733341\|ref\|YP_274475.1\| alkyl hydroperoxide reductase, F subunit [Pseudomonas syringae pv. phas...	0.0	[1..520]	[1..519]
gi\|23471827, gi\|... - gi\|66046205\|ref\|YP_236046.1\| FAD-dependent pyridine nucleotide-disulphide oxidoreductase [Pseudomona...	0.0	[1..520]	[1..519]

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Predicted Domain #1

Region A:
Residues: [1-521]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDANLKTQL KAYLEKVSQP FEIVASLDDS DKSRELLGLL QDIVGLTDKI TLKTDGSDAR  60
   61 KPSFSLNRPG ADIGLRFAGI PMGHEFTSLV LALLQVGGHP SKLDADVIEQ VKGIEGTFEF 120
  121 ETYFSLSCQN CPDVVQALNL MAVLNPNIRH VAIDGALFQD EVEARQIMSV PSIYLNGEVF 180
  181 GQGRMGVEEI LAKIDTGAAA RDAEKLTARD AFDVLVVGGG PAGAAAAIYA ARKGIRTGVA 240
  241 AERFGGQVLD TMAIENFISV QETEGPKLAR ALEEHVRHYE VDIMNLQRAS KLVPAKNAGE 300
  301 LHEVRFESGG SLKAKTLILA TGARWREMGV PGEQEYKAKG VCFCPHCDGP LFKGKRVAVI 360
  361 GGGNSGVEAA IDLAGIVAHV TLLEFDSKLR ADAVLQRKLY SLPNVEVITS ALTSEVKGDG 420
  421 QKVTGLVYKD RNSEEFKSIE LEGIFVQIGL LPNTEWLKGS VELSPRGEII VDARGETSLP 480
  481 GIFAAGDVTT VPYKQIVIAV GEGAKASLSA FDHLIRTSAP E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.0
Match:	1hyuA
Description:	Alkyl hydroperoxide reductase subunit F (AhpF), C-terminal domains; Alkyl hydroperoxide reductase subunit F (AhpF), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alkyl hydroperoxide reductase activity	4.29610283853788	bayes_pls_golite062009
antioxidant activity	3.8464796631544	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.23310780102446	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
transcription regulator activity	1.90357236955554	bayes_pls_golite062009
selenium binding	1.67987004910726	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
transporter activity	0.775169788737542	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.69501605197281	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
hydrolase activity	0.517269321619613	bayes_pls_golite062009
transmembrane transporter activity	0.516718923379533	bayes_pls_golite062009
substrate-specific transporter activity	0.198172638251773	bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity	0.1498172520052	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: