YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30257565, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	347 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257565, gi|....

Description	E-value	Query Range	Subject Range
gi\|167038831, gi... - gi\|167038831\|ref\|YP_001661816.1\| periplasmic binding protein/LacI transcriptional regulator [Thermoa... gi\|242258204, gi... - gi\|242258204\|ref\|ZP_04803030.1\| transcriptional regulator, LacI family [Thermoanaerobacter sp. X513]...	5.0E-70	[3..312]	[32..333]
gi\|20515183, gi\|... - gi\|20806727\|ref\|NP_621898.1\| transcriptional regulator [Thermoanaerobacter tengcongensis MB4], gi\|20... gi\|20806727 - gi\|20806727\|ref\|NP_621898.1\| Transcriptional regulator [Thermoanaerobacter tengcongensis MB4] gi\|254478068, gi... - gi\|254478068\|ref\|ZP_05091451.1\| Periplasmic binding proteins and sugar binding domain of the LacI fa...	1.0E-69	[3..312]	[32..333]
gi\|51891908, gi\|... - gi\|51891908\|ref\|YP_074599.1\| LacI family transcriptional repressor [Symbiobacterium thermophilum IAM...	5.0E-68	[2..311]	[28..329]
gi\|76797419, gi\|... - gi\|76797419\|ref\|ZP_00779738.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti... gi\|241882990, gi... - gi\|241904637\|ref\|ZP_04789316.1\| transcriptional regulator, LacI family [Thermoanaerobacter brockii s...	5.0E-67	[3..312]	[32..331]
gi\|227014565, gi... - gi\|75827922\|ref\|ZP_00757357.1\| COG1609: Transcriptional regulators [Vibrio cholerae O395], gi\|227119... gi\|116217435, gi... - gi\|75824019\|ref\|ZP_00753489.1\| COG1609: Transcriptional regulators [Vibrio cholerae RC385], gi\|25422... gi\|229369436, gi... - gi\|229606781\|ref\|YP_002877429.1\| transcriptional (co)regulator CytR [Vibrio cholerae MJ-1236], gi\|22... gi\|194537429, gi... - gi\|75819862\|ref\|ZP_00749925.1\| COG1609: Transcriptional regulators [Vibrio cholerae V51], gi\|2542254... gi\|229335030, gi... - gi\|229527398\|ref\|ZP_04416790.1\| transcriptional (co)regulator CytR [Vibrio cholerae 12129(1)], gi\|22... gi\|121727573, gi... - gi\|75816601\|ref\|ZP_00747067.1\| COG1609: Transcriptional regulators [Vibrio cholerae V52], gi\|1217275... gi\|121590909, gi... - gi\|121590909\|ref\|ZP_01678231.1\| transcriptional repressor, LacI family [Vibrio cholerae 2740-80], gi... gi\|229341336, gi... - gi\|229521742\|ref\|ZP_04411160.1\| transcriptional (co)regulator CytR [Vibrio cholerae TM 11079-80], gi... gi\|124115534, gi... - gi\|153213964\|ref\|ZP_01949157.1\| transcriptional repressor, LacI family [Vibrio cholerae 1587], gi\|12... gi\|229516926, gi... - gi\|229516926\|ref\|ZP_04406372.1\| transcriptional (co)regulator CytR [Vibrio cholerae RC9], gi\|2293459... gi\|153221073, gi... - gi\|153221073\|ref\|ZP_01952128.1\| transcriptional repressor, LacI family [Vibrio cholerae MAK 757], gi... gi\|229513597, gi... - gi\|229513597\|ref\|ZP_04403061.1\| transcriptional (co)regulator CytR [Vibrio cholerae TMA 21], gi\|2293... gi\|153819925, gi... - gi\|153819925\|ref\|ZP_01972592.1\| transcriptional repressor, LacI family [Vibrio cholerae NCTC 8457], ... gi\|229354780, gi... - gi\|229507275\|ref\|ZP_04396780.1\| transcriptional (co)regulator CytR [Vibrio cholerae BX 330286], gi\|2... gi\|229353276, gi... - gi\|229509802\|ref\|ZP_04399283.1\| transcriptional (co)regulator CytR [Vibrio cholerae B33], gi\|2293532... gi\|227010681, gi... - gi\|227082793\|ref\|YP_002811344.1\| transcriptional repressor, LacI family [Vibrio cholerae M66-2], gi\|... gi\|15642672, gi\|... - gi\|9657271\|gb\|AAF95818.1\| transcriptional repressor, LacI family [Vibrio cholerae O1 biovar El Tor s... gi\|11277455 - pir\|\|H82046 transcription repressor LacI family VC2677 [imported] - Vibrio cholerae (strain N16961 s... gi\|148875055, gi... - gi\|153829472\|ref\|ZP_01982139.1\| transcriptional repressor, LacI family [Vibrio cholerae 623-39], gi\|... gi\|197752626, gi... - gi\|254285869\|ref\|ZP_04960831.1\| transcriptional repressor, LacI family [Vibrio cholerae AM-19226], g... gi\|254846919, gi... - gi\|75830092\|ref\|ZP_00759377.1\| COG1609: Transcriptional regulators [Vibrio cholerae MO10], gi\|254851... gi\|153825116, gi... - gi\|153825116\|ref\|ZP_01977783.1\| transcriptional repressor, LacI family [Vibrio cholerae MZO-2], gi\|1...	1.0E-66	[5..317]	[32..335]
gi\|37200774, gi\|... - gi\|37676233\|ref\|NP_936629.1\| transcriptional regulator [Vibrio vulnificus YJ016], gi\|37200774\|dbj\|BA...	2.0E-66	[3..311]	[30..331]
gi\|27366525, gi\|... - gi\|27366525\|ref\|NP_762052.1\| transcriptional regulator [Vibrio vulnificus CMCP6], gi\|27358091\|gb\|AAO...	3.0E-66	[3..311]	[30..331]
gi\|83745729, gi\|... - gi\|83745729\|ref\|ZP_00942786.1\| Transcriptional regulator, LacI family [Ralstonia solanacearum UW551]... gi\|207743639, gi... - gi\|207743639\|ref\|YP_002260031.1\| transcriptional regulatory dna-binding repressor protein [Ralstonia...	3.0E-66	[4..311]	[31..337]
gi\|82401152, gi\|... - gi\|82500860\|ref\|ZP_00886253.1\| regulatory protein, LacI [Caldicellulosiruptor saccharolyticus DSM 89...	3.0E-66	[3..311]	[40..338]

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Predicted Domain #1

Region A:
Residues: [1-347]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRKLGIVFI VCICLIGLIA CSSQTADKKK ADDVKFAFIP KLTGVGFFTS GGEGAKEMGD  60
   61 KLGVQVKYDG PSEASVSGQV KYINNFINQN YDALMVSSTS VDGLSQSLQR AKKKGMTVLT 120
  121 WDSDVNPKDR SFYISQGTPD QLANLLIEMT SKQIGDKGKV AFFYSSPTVT DQNQWVTKAK 180
  181 EIIKEKYPNW EIVTTQYGEN NAQKSLSVGE NILKTYPDIN AVICPDATAL PAMAQAAENL 240
  241 KMDKKVVVTG FSTPNVMRDY VKRGTVQQFG LWDVKQQGAL ATYVANEIVV KGKKLKVGDS 300
  301 FEVKGIGKVK VEPNSIQGYD YEAEGNGIIV LPERVVFTKD NIDKYNF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	1tjyA
Description:	Crystal Structure of Salmonella typhimurium AI-2 receptor LsrB in complex with R-THMF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate transmembrane transporter activity	1.15685021131727	bayes_pls_golite062009
binding	1.13059008752468	bayes_pls_golite062009
transporter activity	0.399752289774857	bayes_pls_golite062009
transmembrane transporter activity	0.265529619623159	bayes_pls_golite062009
sugar transmembrane transporter activity	0.23981626136031	bayes_pls_golite062009
active transmembrane transporter activity	0.0415259877073471	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: